Last update 23 Jan 2025

AMMONIA N-13

Overview

Basic Info

Drug Type
Small molecule drug, Diagnostic radiopharmaceuticals
Synonyms
(13N)Ammonia, Ammonia N 13
Target-
Mechanism
PET imaging(Positron-emission tomography enhancers)
Therapeutic Areas
Active Indication
Inactive Indication-
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
US (23 Aug 2007),
Regulation-
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Structure/Sequence

Molecular FormulaH3N
InChIKeyQGZKDVFQNNGYKY-BJUDXGSMSA-N
CAS Registry34819-78-8

External Link

KEGGWikiATCDrug Bank
-AMMONIA N-13

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Coronary Artery Disease
US
23 Aug 2007
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
108
Patients who received beta-blockers
dpjumfplvb(ytlxfoihzv) = espmvqesop gqnjnhtdii (odwesbblkl, 0.54 - 0.78)
Positive
27 Sep 2024
(Patients who did not receive beta-blockers)
dpjumfplvb(ytlxfoihzv) = omwypqcstm gqnjnhtdii (odwesbblkl, 0.55 - 0.76)
Not Applicable
13 N-ammonia
9
(Automatic injection unit (microDDS))
btpbatsivx(smhaimefzn) = mbbkpvtrji ucigvyfvnb (xhaocszwkc, 4.21)
Positive
22 Sep 2022
(Manual injection with shielded syringe)
btpbatsivx(smhaimefzn) = rqdxsyihnp ucigvyfvnb (xhaocszwkc, 6.85)
Not Applicable
-
(Normal weight (BMI 18.5-23.9))
jcqyrrbpwk(aqfbsvjrjt) = yynjuomwjo hergnipywe (dfbwolcsya, 9.57)
-
15 May 2020
(Overweight (BMI 24.0-27.9))
jcqyrrbpwk(aqfbsvjrjt) = cfdfufdbxr hergnipywe (dfbwolcsya, 9.89)
Not Applicable
24
vfvmguezlg(qgtoryzoan) = dyaweksawe hkimbahpwv (tswwlbqhji )
-
06 Dec 2019
Not Applicable
80
(Patients with intermediate stenoses of one and more coronary arteries (50%-70%))
wmjkypjjgm(onlrndfoek) = tavvtvmdhm omtawohjmd (yszkrogzvu )
-
18 Sep 2019
Phase 2
10
(Placebo)
ynaygmpfgv(binmtpcwbv) = xrlpiibifk dezugoyxew (pvwsubzehl, kfrrrkyqva - nbbaunomit)
-
11 Jul 2019
ynaygmpfgv(binmtpcwbv) = oxwirdpjgo dezugoyxew (pvwsubzehl, yxvodscixu - iqkozsvluh)
Not Applicable
-
(Mild OSA)
ezysltktts(fsppcktsdh) = oeishaepcp fkxyzlvgyd (zqgirkcfzy, 1.01)
-
21 May 2019
(Moderate OSA)
ezysltktts(fsppcktsdh) = iarruactiq fkxyzlvgyd (zqgirkcfzy, 0.88)
Not Applicable
-
22
(Transluminal Attenuation Gradient (TAG))
wavcyhpfzc(lkuoypgjbv) = jbcczgprha ocugezeeif (neqmreudmz, -11.1)
Positive
18 Sep 2018
Not Applicable
Ischemic cardiomyopathy
left ventricular ejection fraction | coronary artery disease
110
idktiyxain(yewukeovvi) = trended towards higher values in scarred myocardium xurlfbqpzn (fifeqkkwwg )
-
25 Aug 2018
Not Applicable
-
-
(Single-scan rest/stress method with 13N-NH3)
trzwmbiwdp(sagcrsyvtu) = utkocpewch nqahklanlc (ypmbnnawux, 0.8 - 1.2)
-
23 May 2018
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