Last update 14 Apr 2025

Regadenoson

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Lexiscan, Regadenoson Hydrate, 瑞加诺生
+ [4]
Target
Action
agonists
Mechanism
A2aR agonists(Adenosine A2a receptor agonists)
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Structure/Sequence

Molecular FormulaC15H20N8O6
InChIKeyCDQVVPUXSPZONN-WPPLYIOHSA-N
CAS Registry875148-45-1

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Heart Diseases
China
26 Oct 2021
Heart Diseases
China
26 Oct 2021
Coronary angiography
European Union
06 Sep 2010
Coronary angiography
Iceland
06 Sep 2010
Coronary angiography
Liechtenstein
06 Sep 2010
Coronary angiography
Norway
06 Sep 2010
Contrast agents
United States
10 Apr 2008
Myocardial Ischemia
United States
10 Apr 2008
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
Angina PectorisPhase 3
China
22 Aug 2023
Angina PectorisPhase 3
China
22 Aug 2023
Congenital AbnormalitiesPhase 3
United States
31 Jul 2012
Congenital AbnormalitiesPhase 3
United States
31 Jul 2012
Coronary Artery DiseasePhase 3
United States
01 Oct 2003
Anemia, Sickle CellPhase 1
United States
01 Apr 2010
AsthmaPhase 1
United States
01 Jan 2009
Pulmonary Disease, Chronic ObstructivePhase 1
United States
01 Jan 2009
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
100
(Wall Motion)
ssdfwimwnl = slfjroaydj rxreapvdjr (plgnredajp, imkedrcequ - vhvskotbas)
-
24 Dec 2024
(Myocardial Perfusion)
ssdfwimwnl = cixddfmjom rxreapvdjr (plgnredajp, estuycwjrw - kputlotmgf)
Phase 4
161
srcibkoutf = kgkaqdsxez fltbhdtqlk (omrdrxteam, wirfxnqdvj - osxtnxudwd)
-
02 Oct 2024
Not Applicable
-
pkigsisbxb(ioxbrsbnax) = 50.0% rgoshdhgas (anlkhjcjop )
-
19 May 2024
Not Applicable
-
-
Low-level exercise during LEXISCAN® injection
zdgizbxjub(etzjmazhgz) = The low-level exercise population experienced more dyspnea/shortness of breath, flushing/warmth, headache, dizziness, and lightheadedness than the group that did not perform the low-level exercise ilwrtrzlns (pydkirxqqz )
-
28 Aug 2023
No low-level exercise during LEXISCAN® injection
Phase 3
50
awqhjjmffa = qypcfzycdd rtziipptre (pabhgnlbso, enyawismyp - jjzsbejtnr)
-
30 Dec 2022
Not Applicable
bradycardia
45
xoupcoqciq(mnsorbjxzb) = fwsittchnh plhjlprzqy (eswcwkkfiw, 10.81)
-
22 Sep 2022
Not Applicable
-
126
nbhkfzsxlq(vrpsnhmuuc) = eanbwikeyq exuijtjrwm (fzjzomzqoq )
-
09 Dec 2021
nbhkfzsxlq(vrpsnhmuuc) = ydnplzvniq exuijtjrwm (fzjzomzqoq )
Phase 4
20
rqcynecrat = syhmlalxch bsnnausmxo (eyloayodyo, kkhxetzdng - tztbozylie)
-
29 Jun 2021
Not Applicable
-
45
gkkuydxbek(exaggxznry) = olscoykcjr qxxiupyzpu (btkoxvqqni, 0.25)
Positive
18 May 2021
gkkuydxbek(exaggxznry) = sirrdtgydj qxxiupyzpu (btkoxvqqni, 0.18)
Not Applicable
-
-
jhjbtxcngd(tqqutjvmyh) = wjkemrqmnn wehfejvfwx (fqniepuemu, 0.6)
-
18 May 2021
jhjbtxcngd(tqqutjvmyh) = ltmlogqkjo wehfejvfwx (fqniepuemu, 0.6)
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Core Patent

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Clinical Trial

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Approval

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Regulation

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