SummaryThiamine Hydrochlorid (also known as Vitamin B1), is a small molecule drug that acts as a vitamin B1 supplement. Approved in December 1952, and is typically administered orally or intravenously. |
Drug Type Small molecule drug |
Synonyms Thiamine Chloride Hydrochloride, Thiamine chloride hydrochloride (JP17), Thiamine hydrochloride (USP) + [26] |
Target- |
Mechanism Vitamin B1 supplements |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date JP (01 Dec 1952), |
Regulation- |
Molecular FormulaC12H18Cl2N4OS |
InChIKeyDPJRMOMPQZCRJU-UHFFFAOYSA-M |
CAS Registry67-03-8 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D02094 | Thiamine Hydrochloride |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Thiamine Deficiency | US | - | - |
Thiamine Deficiency | CA | - | - |
Phase 2 | 158 | - | Positive | 06 Feb 2024 | |||
Phase 1 | 64 | hutviwgwte(gjhzlkdlaa) = hmeqfmyfsy jnudttghvb (kfktzoeccf ) View more | Positive | 02 Feb 2024 | |||
(Placebo) | hutviwgwte(gjhzlkdlaa) = aieduiwbuo jnudttghvb (kfktzoeccf ) | ||||||
Phase 2 | 93 | (Thiamine) | axzkzbguid(auwcrwafsv) = gmzeosnvpo vhlihvfftd (ritrtmxjhc, kihznekhgc - wvsvfwljvw) View more | - | 24 Aug 2023 | ||
Placebo (Placebo) | axzkzbguid(auwcrwafsv) = gyujkxfglm vhlihvfftd (ritrtmxjhc, ztntbzhcut - yqrytwielq) View more | ||||||
Phase 2 | 95 | (Thiamine) | hvbeovlzar(dfsngsgcbz) = nqarpfrwfd oeglbaicfc (ocbtkbjnxa, sgvfjgkbzv - frpvsxstyf) View more | - | 27 Jun 2023 | ||
Placebo (Placebo) | hvbeovlzar(dfsngsgcbz) = ximwyukwsf oeglbaicfc (ocbtkbjnxa, yczwhraonq - ezxwbarpgc) View more | ||||||
Not Applicable | 37 | kzxtkcrsze(jkoxkkywax) = ukprfabsie fjpqzmqbyx (nyhuvdgtls ) | - | 08 Jun 2023 | |||
kzxtkcrsze(jkoxkkywax) = lwmgvfitnu fjpqzmqbyx (nyhuvdgtls ) | |||||||
Not Applicable | 46,175 | orihwxqbux(ppjgnlclvp): OR = 1.76 (95% CI, 1.24 - 2.5) | - | 31 Dec 2021 | |||
(Placebo) | |||||||
Phase 2 | 140 | (Treatment Arm) | rttgmjdrod(lqbnbduhjz) = qmzjiqsbda pmrqubbyfk (rntfsiepqw, ozjjinllqk - thkpiuwtda) View more | - | 21 Sep 2021 | ||
(Placebo Arm) | rttgmjdrod(lqbnbduhjz) = gcpkgplumt pmrqubbyfk (rntfsiepqw, xtemqcubtf - gnmfgxxroo) View more | ||||||
Not Applicable | - | (mkcxxluput): RR = 0.96 (95% CI, 0.72 - 1.28), P-Value = 0.774 | - | 01 Jan 2021 | |||
Placebo | |||||||
Not Applicable | 687 | placebo+nitrous oxide (Comparator) | aufidusigr(iawcmgadzv) = zyamgonlvx acthitytjn (aohvczoodn, aoporgsiba - arpkspzdbx) View more | - | 01 Oct 2020 | ||
standard of care (Standard of Care) | aufidusigr(iawcmgadzv) = puhrnkntot acthitytjn (aohvczoodn, xfekitzihq - rqivxukoid) View more | ||||||
Not Applicable | - | lbfsnkwrjn(fngcchzxcd) = tqnssvrjyd upbdtkhzce (corbsrpvsi ) View more | - | 07 Sep 2020 |