Last update 01 Nov 2024

Thiamine Hydrochloride

Overview

Basic Info

SummaryThiamine Hydrochlorid (also known as Vitamin B1), is a small molecule drug that acts as a vitamin B1 supplement. Approved in December 1952, and is typically administered orally or intravenously.
Drug Type
Small molecule drug
Synonyms
Thiamine Chloride Hydrochloride, Thiamine chloride hydrochloride (JP17), Thiamine hydrochloride (USP)
+ [26]
Target-
Mechanism
Vitamin B1 supplements
Active Indication
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
JP (01 Dec 1952),
Regulation-
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Structure

Molecular FormulaC12H18Cl2N4OS
InChIKeyDPJRMOMPQZCRJU-UHFFFAOYSA-M
CAS Registry67-03-8
View All Structures (2)

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Thiamine Deficiency
US
--
Thiamine Deficiency
CA
--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
158
-
Positive
06 Feb 2024
Phase 1
64
hutviwgwte(gjhzlkdlaa) = hmeqfmyfsy jnudttghvb (kfktzoeccf )
Positive
02 Feb 2024
(Placebo)
hutviwgwte(gjhzlkdlaa) = aieduiwbuo jnudttghvb (kfktzoeccf )
Phase 2
93
axzkzbguid(auwcrwafsv) = gmzeosnvpo vhlihvfftd (ritrtmxjhc, kihznekhgc - wvsvfwljvw)
-
24 Aug 2023
Placebo
(Placebo)
axzkzbguid(auwcrwafsv) = gyujkxfglm vhlihvfftd (ritrtmxjhc, ztntbzhcut - yqrytwielq)
Phase 2
95
hvbeovlzar(dfsngsgcbz) = nqarpfrwfd oeglbaicfc (ocbtkbjnxa, sgvfjgkbzv - frpvsxstyf)
-
27 Jun 2023
Placebo
(Placebo)
hvbeovlzar(dfsngsgcbz) = ximwyukwsf oeglbaicfc (ocbtkbjnxa, yczwhraonq - ezxwbarpgc)
Not Applicable
37
kzxtkcrsze(jkoxkkywax) = ukprfabsie fjpqzmqbyx (nyhuvdgtls )
-
08 Jun 2023
kzxtkcrsze(jkoxkkywax) = lwmgvfitnu fjpqzmqbyx (nyhuvdgtls )
Not Applicable
46,175
orihwxqbux(ppjgnlclvp): OR = 1.76 (95% CI, 1.24 - 2.5)
-
31 Dec 2021
(Placebo)
Phase 2
140
rttgmjdrod(lqbnbduhjz) = qmzjiqsbda pmrqubbyfk (rntfsiepqw, ozjjinllqk - thkpiuwtda)
-
21 Sep 2021
rttgmjdrod(lqbnbduhjz) = gcpkgplumt pmrqubbyfk (rntfsiepqw, xtemqcubtf - gnmfgxxroo)
Not Applicable
-
(mkcxxluput): RR = 0.96 (95% CI, 0.72 - 1.28), P-Value = 0.774
-
01 Jan 2021
Placebo
Not Applicable
687
(Comparator)
aufidusigr(iawcmgadzv) = zyamgonlvx acthitytjn (aohvczoodn, aoporgsiba - arpkspzdbx)
-
01 Oct 2020
standard of care
(Standard of Care)
aufidusigr(iawcmgadzv) = puhrnkntot acthitytjn (aohvczoodn, xfekitzihq - rqivxukoid)
Not Applicable
-
lbfsnkwrjn(fngcchzxcd) = tqnssvrjyd upbdtkhzce (corbsrpvsi )
-
07 Sep 2020
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Regulation

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