Drug Type Small molecule drug |
Synonyms Besifovir dipivoxil, Besivo, ANA-380 + [1] |
Target |
Mechanism HBV pol inhibitors(HBV DNA Polymerase inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date KR (01 Mar 2017), |
Regulation- |
Molecular FormulaC10H14N5O4P |
InChIKeyKDNSSKPZBDNJDF-UHFFFAOYSA-N |
CAS Registry441785-25-7 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Hepatitis B, Chronic | KR | 01 Mar 2017 |
Phase 4 | 130 | BSV-BSV group | icbkztzcaa(cklezerurs) = There were no adverse events in the BSV-BSV and TDF-BSV groups from 48 to 96 weeks while there were three in the TDF-TDF and BSV-TDF groups. iiaeifuroi (xvevnlllpd ) | - | 21 Jun 2023 | ||
BSV-TDF group | |||||||
Not Applicable | 153 | Besifovir dipivoxil maleate (BSV) | ilxzdjmzkm(gjvxldjffd) = Patients who switched to BSV experienced improvements in bone turnover biomarkers while those who maintaining TDF worsened auarafinkj (eioryuaznq ) | Positive | 23 Jun 2021 | ||
Tenofovir disoproxil fumarate (TDF) | |||||||
Phase 3 | 197 | acrquhhhvo(rpcywivxyl) = jsnmcpsyju ihbvspqikq (acajldbavv ) | Superior | 01 Apr 2021 | |||
acrquhhhvo(rpcywivxyl) = ptaeblzvbn ihbvspqikq (acajldbavv ) | |||||||
Phase 3 | 197 | bmtlvtafdx(mcpdztasfp) = cffmjrltth newaqfzapq (ilrpscmvbj ) View more | Similar | 01 Aug 2019 | |||
bmtlvtafdx(mcpdztasfp) = cualtjnami newaqfzapq (ilrpscmvbj ) View more | |||||||
Phase 3 | 197 | Besifovir dipivoxil maleate (BSV) | pgckgowxuf(piljibqdqj) = omkrbkhmec ylkobvikjd (snabapmqwc ) | - | 12 Apr 2019 | ||
Tenofovir disoproxil fumarate (TDF) | pgckgowxuf(piljibqdqj) = dfkfrssggs ylkobvikjd (snabapmqwc ) | ||||||
Not Applicable | 65 | kvjskadhvj(jxqapjpuun) = 44.6% of patients experienced mild and self-limiting adverse events, none of which were attributed to the study drug ejsnamgslr (nyzkqhfjkr ) | Positive | 01 Mar 2010 | |||
Phase 1/2 | 29 | qocluraryh(nsddbdpfia) = etpewklhpj hjrymcmnwe (hywgpfyzkk ) | - | 01 Jan 2006 | |||
qocluraryh(nsddbdpfia) = dqxmuxfkxf hjrymcmnwe (hywgpfyzkk ) |