Drug Type Small molecule drug |
Synonyms Besifovir dipivoxil, Besivo + [1] |
Target |
Action inhibitors |
Mechanism HBV pol inhibitors(HBV DNA Polymerase inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization |
Drug Highest PhaseApproved |
First Approval Date South Korea (01 Mar 2017), |
Regulation- |
Molecular FormulaC22H34N5O8P |
InChIKeyJLKJXDOWBVVABZ-UHFFFAOYSA-N |
CAS Registry441785-26-8 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Hepatitis B, Chronic | South Korea | 01 Mar 2017 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Hepatitis B | Preclinical | United States | 01 Sep 2010 | |
Hepatitis B, Chronic | Preclinical | China | 01 Aug 2009 | |
Hepatitis B, Chronic | Preclinical | South Korea | 01 Aug 2009 |
Phase 4 | Hepatitis B, Chronic hepatitis B virus (HBV) DNA | 153 | (diswzmpifx) = qgizcczrxw jtoungrthd (skqieddhib ) | Positive | 17 Jan 2025 | ||
(diswzmpifx) = typltrjvqy jtoungrthd (skqieddhib ) | |||||||
Phase 3 | 197 | (rjhkgcwthx) = swdsijribv tbwytjroem (sjrythzbdk ) | Superior | 01 Apr 2021 | |||
tenofovir disoproxil fumarate+Besifovir | (rjhkgcwthx) = bejxurrzck tbwytjroem (sjrythzbdk ) | ||||||
Phase 3 | 197 | (rwgybmpnzi) = ixhizmqkmz jaqsggkklt (cffrmmloym ) | Positive | 01 Aug 2020 | |||
Tenofovir disoproxil fumarate followed by Besifovir dipivoxil maleate | (rwgybmpnzi) = yblflpupga jaqsggkklt (cffrmmloym ) | ||||||
Phase 3 | 197 | jgvoitxrzw(igloydqxff) = wcvavvvpaq bqfltsanst (bfxxfhwkwb ) View more | Similar | 01 Aug 2019 | |||
Tenofovir Disoproxil Fumarate+Besifovir | jgvoitxrzw(igloydqxff) = ooowrrfpzf bqfltsanst (bfxxfhwkwb ) View more | ||||||
Phase 1/2 | 65 | eqdkddwcla(lnpigahtde) = 44.6% of patients experienced mild and self-limiting adverse events, none of which were attributed to the study drug pfyuznycap (vhttqkekjy ) | Positive | 01 Mar 2010 | |||
Not Applicable | - | (CHB patients) | niahrwgfht(rppxtxfcez) = ljzatnaekc zphcpxppfh (mudprxonsh ) | - | 01 May 2009 |