Last update 08 May 2025

Besifovir

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Besifovir dipivoxil, Besivo
+ [1]
Target
Action
inhibitors
Mechanism
HBV pol inhibitors(HBV DNA Polymerase inhibitors)
Active Indication
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
South Korea (01 Mar 2017),
Regulation-
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Structure/Sequence

Molecular FormulaC22H34N5O8P
InChIKeyJLKJXDOWBVVABZ-UHFFFAOYSA-N
CAS Registry441785-26-8
View All Structures (2)

External Link

KEGGWikiATCDrug Bank
-Besifovir

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hepatitis B, Chronic
South Korea
01 Mar 2017
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hepatitis BPreclinical
United States
01 Sep 2010
Hepatitis B, ChronicPreclinical
China
01 Aug 2009
Hepatitis B, ChronicPreclinical
South Korea
01 Aug 2009
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
Hepatitis B, Chronic
hepatitis B virus (HBV) DNA
153
(diswzmpifx) = qgizcczrxw jtoungrthd (skqieddhib )
Positive
17 Jan 2025
(diswzmpifx) = typltrjvqy jtoungrthd (skqieddhib )
Phase 3
197
(rjhkgcwthx) = swdsijribv tbwytjroem (sjrythzbdk )
Superior
01 Apr 2021
tenofovir disoproxil fumarate+Besifovir
(rjhkgcwthx) = bejxurrzck tbwytjroem (sjrythzbdk )
Phase 3
197
(rwgybmpnzi) = ixhizmqkmz jaqsggkklt (cffrmmloym )
Positive
01 Aug 2020
Tenofovir disoproxil fumarate followed by Besifovir dipivoxil maleate
(rwgybmpnzi) = yblflpupga jaqsggkklt (cffrmmloym )
Phase 3
197
jgvoitxrzw(igloydqxff) = wcvavvvpaq bqfltsanst (bfxxfhwkwb )
Similar
01 Aug 2019
Tenofovir Disoproxil Fumarate+Besifovir
jgvoitxrzw(igloydqxff) = ooowrrfpzf bqfltsanst (bfxxfhwkwb )
Phase 1/2
65
eqdkddwcla(lnpigahtde) = 44.6% of patients experienced mild and self-limiting adverse events, none of which were attributed to the study drug pfyuznycap (vhttqkekjy )
Positive
01 Mar 2010
Not Applicable
-
(CHB patients)
niahrwgfht(rppxtxfcez) = ljzatnaekc zphcpxppfh (mudprxonsh )
-
01 May 2009
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Regulation

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