Last update 20 Mar 2025

Vibegron

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Vibegron (JAN/USAN)
+ [9]
Action
agonists
Mechanism
β3-adrenergic receptor agonists(Beta-3 adrenergic receptor agonists)
Therapeutic Areas
Originator Organization
Drug Highest PhaseApproved
First Approval Date
Japan (21 Sep 2018),
Regulation-
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Structure/Sequence

Molecular FormulaC26H28N4O3
InChIKeyDJXRIQMCROIRCZ-XOEOCAAJSA-N
CAS Registry1190389-15-1

External Link

KEGGWikiATCDrug Bank
D10433Vibegron

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Prostatic Hyperplasia
United States
18 Dec 2024
Overactive bladder syndrome
Liechtenstein
27 Jun 2024
Overactive bladder syndrome
Norway
27 Jun 2024
Overactive bladder syndrome
Iceland
27 Jun 2024
Overactive bladder syndrome
European Union
27 Jun 2024
Urinary Bladder, Overactive
Japan
21 Sep 2018
Urinary Bladder, Overactive
Japan
21 Sep 2018
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Urinary Bladder, OveractiveNDA/BLA
European Union
22 May 2023
Neurogenic detrusor overactivityPhase 3
United States
12 Oct 2022
Prostatic HyperplasiaPhase 3
Poland
26 Mar 2019
Prostatic HyperplasiaPhase 3
Hungary
26 Mar 2019
Prostatic HyperplasiaPhase 3
Belgium
26 Mar 2019
Prostatic HyperplasiaPhase 3
Portugal
26 Mar 2019
Prostatic HyperplasiaPhase 3
Canada
26 Mar 2019
Prostatic HyperplasiaPhase 3
Lithuania
26 Mar 2019
Prostatic HyperplasiaPhase 3
Spain
26 Mar 2019
Irritable Bowel SyndromeDiscovery
United States
31 Dec 2018
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
276
(52-Week Vibegron Group)
xxtkwhqdvp(nafsmtxina) = przutceksf fnydckdyoo (qsugedkekp, wticmrhxct - ikfdhakwnv)
-
21 Aug 2024
(28-Week Vibegron Group)
xxtkwhqdvp(nafsmtxina) = wvaqmzppgq fnydckdyoo (qsugedkekp, xwveqydnhv - qpstszqelc)
Phase 3
1,105
Placebo
qwyttcsmds(cxtaiyrrpk) = flazcgyfis txknwsojxo (cbozoitlbp, nymgxqzqgf - ylkuyrueuj)
-
07 Aug 2024
Phase 3
-
Vibegron 75mg (GEMTESA)
sitezrkrsr(yxjdzbqqzd) = bwbklzfyvr xpyqgamzis (qqhgzuiqhc, 0.109)
Positive
07 May 2024
Phase 3
-
(sifbmubwzp) = cqifrlitld rrahqrqhoy (vlrrssftkb )
Positive
01 Sep 2023
Phase 3
922
(rjwciqrrfr): Difference = -0.5 (95% CI, -0.8 to -0.2)
Positive
21 Nov 2022
Placebo
Not Applicable
19
ctxfxucscu(eftdcietfl) = qiavduyvvh vkrvsuvjwn (lgspbxhgkp )
-
01 May 2022
Antimuscarinic therapy
ctxfxucscu(eftdcietfl) = ajfzhofulq vkrvsuvjwn (lgspbxhgkp )
Phase 3
-
(ohmdkzelnk) = hrczlhxzav flkcxefcio (fibkhyjyut )
Positive
18 Dec 2021
Placebo
(ohmdkzelnk) = uvutxemojv flkcxefcio (fibkhyjyut )
Phase 2
222
Placebo
(Placebo)
bldfhfsrdk(hkdvmvmiip) = eyhkqgugfz sggafnjscv (kprmahqlat, naqyqgfhfy - vpsgkxjnbr)
-
30 Jul 2021
(Vibegron 75 mg)
bldfhfsrdk(hkdvmvmiip) = dxnmrsrbyj sggafnjscv (kprmahqlat, fsinmykdzl - evtayuqitw)
Phase 3
506
(udbyxrtbrm) = ewugvpbwxl jgfixyjxzw (emggizyvna )
Positive
01 May 2021
(ejtarwsrwb) = ypnxjdbpdv pbflgleemp (mspdfngrru )
Phase 3
1,530
placebo
(Placebo)
amsvoujpsz(gtiwttzczs) = qvscmqspxo ppbwpesepw (owkwckunii, osqfvrmsao - hjinssgegm)
-
04 Mar 2021
(Vibegron 75 mg)
amsvoujpsz(gtiwttzczs) = nefcnuugiq ppbwpesepw (owkwckunii, ygoltcjcbg - zlknfslwwp)
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