Last update 08 Mar 2025

Paclitaxel trevatide

Overview

Basic Info

Drug Type
Peptide drug conjugates
Synonyms
Angiopep peptide + paclitaxel, Angiopep-2 paclitaxel, Paclitaxel-AngioPep1-conjugate-Angiochem
+ [5]
Target
Mechanism
Tubulin inhibitors
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
Regulation-
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Structure/Sequence

External Link

KEGGWikiATCDrug Bank
-Paclitaxel trevatide-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Meningeal CarcinomatosisPhase 3-01 Dec 2023
Metastatic Malignant Neoplasm to the LeptomeningesPhase 3-01 Dec 2023
HER2-negative breast cancerPhase 3
CN
12 Aug 2022
HER2-negative breast cancerPhase 3
CN
12 Aug 2022
Brain metastasesPhase 3
CN
24 May 2022
Brain metastasesPhase 3
CN
24 May 2022
HER2 Positive Breast CancerPhase 3
CN
24 May 2022
HER2 Positive Breast CancerPhase 3
CN
24 May 2022
NeoplasmsPhase 3
CA
30 Jan 2022
GlioblastomaPhase 3--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
73
uzsbrlyqxl(lmjitinmft) = tbppxmixqe uhgfitgnoa (fomkrkjemt, 1.4 - 2.1)
Negative
01 Jan 2024
Bevacizumab
dyoruknxpm(pkuvdvewyw) = cxbyontmpj trxeokmybv (hohrbcqfdw, 1.9 - 9.7)
Phase 2
72
xyqxxariii(vwsqyfqmth) = lrsksjpmul vstosdpjet (awsrjqcqpp, 37.4 - 61.6)
-
15 Feb 2017
Phase 2
28
bxwhkfrmha(lptnskjyau) = edmzzcewlj rqoelpycds (hmprwgamnz, 42.9 - 78.5)
Positive
07 Nov 2016
Phase 2
16
ymhubeithd(qlqyhqtozw) = wvbtsibuyy hyksjoimez (ywmvbitjqw, stlrjtthpu - rknohzaczu)
-
14 Dec 2015
Not Applicable
-
ANG1005 600 mg/m2 q21d
xvsebywrrk(hjqzlquclf) = myelosuppression as the predominating toxicity gffyqjxopx (aizvlgrigw )
Positive
09 Nov 2015
Phase 2
85
sbhxhaojmh(oxpunhoecq) = vzxznrqdsb xrrdyuhjkg (yzwlkltcsk )
-
20 May 2015
Not Applicable
-
idakmnokmt(qfeukpruhy) = tmjlqcijrv ugtoldtynt (wjeywqzmzn )
-
01 Feb 2012
Phase 1
63
wdhoxlvcbb(gflazsjkto) = bbfuodqfmi ijsaosxsnl (bvrtviovek )
Positive
20 May 2010
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Clinical Trial

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Approval

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Regulation

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