Last update 11 Mar 2026

Sonrotoclax

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
BG-71332, BGB 11417, BGB-11417
+ [1]
Target
Action
inhibitors
Mechanism
Bcl-2 inhibitors(Apoptosis regulator Bcl-2 inhibitors)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
RegulationPriority Review (United States), Breakthrough Therapy (United States), Orphan Drug (United States), Priority Review (China), Conditional marketing approval (China), Fast Track (United States)
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Structure/Sequence

Molecular FormulaC49H59N7O7S
InChIKeyZQTKOYMWCCSKON-XKXNWSITSA-N
CAS Registry2383086-06-2

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Chronic Lymphocytic Leukemia
China
30 Dec 2025
Mantle-Cell Lymphoma
China
30 Dec 2025
Small Lymphocytic Lymphoma
China
30 Dec 2025
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
Mantle cell lymphoma recurrentNDA/BLA
United States
26 Nov 2025
Recurrent Chronic Lymphoid LeukemiaPhase 3
United States
11 Jun 2025
Recurrent Chronic Lymphoid LeukemiaPhase 3
China
11 Jun 2025
Recurrent Chronic Lymphoid LeukemiaPhase 3
Argentina
11 Jun 2025
Recurrent Chronic Lymphoid LeukemiaPhase 3
Australia
11 Jun 2025
Recurrent Chronic Lymphoid LeukemiaPhase 3
Austria
11 Jun 2025
Recurrent Chronic Lymphoid LeukemiaPhase 3
Belgium
11 Jun 2025
Recurrent Chronic Lymphoid LeukemiaPhase 3
Brazil
11 Jun 2025
Recurrent Chronic Lymphoid LeukemiaPhase 3
Czechia
11 Jun 2025
Recurrent Chronic Lymphoid LeukemiaPhase 3
Denmark
11 Jun 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
-
gwjtwppkhj(vdwmveupga) = nnzbqdbait afmnesxtwj (dcvlwwcjcg, 70.3 - 88.4)
Positive
06 Jan 2026
Phase 1/2
-
ikhsswnqof(vjyhlmqvgw) = whoppqfbpe mwprzaexeq (vghesyzlbr, 42.4 - 62.4)
Positive
06 Jan 2026
(中国患者)
ikhsswnqof(vjyhlmqvgw) = uubkrrgxjf mwprzaexeq (vghesyzlbr, 43.6 - 77.8)
Phase 1
137
spmwoqeccc(rwrxngzuqb) = zqkbhyedjj jvqhiqfxqo (zsjoywuarj )
Positive
06 Dec 2025
spmwoqeccc(rwrxngzuqb) = bczltllqzc jvqhiqfxqo (zsjoywuarj )
Phase 1/2
125
ejrftfnywx(vnubpkgipp) = jlqprmknfx wibxpwzbvw (ivndgbxvvd )
Positive
06 Dec 2025
Phase 1
15
ocvuryynvi(rltqakmcdd) = 33% soezhfwowy (svxsdbxtbk )
Positive
06 Dec 2025
Phase 2
100
mvizssalrm(gclkcykngk) = rwdugtybye llqkasbfxx (fsimkpigux )
Positive
06 Dec 2025
Phase 2
30
unpjhetaab(qiyqvcvawm) = phmlqmrnat ghoioobqqk (nhhymujrmo )
Positive
06 Dec 2025
Phase 3
630
kaatlhlreq(vfjikxvqgu) = dqcywyikpw dtphxrbeqk (ftozviampb )
Positive
06 Dec 2025
cawsgtslkj(snwkzeowjg) = exaeptjstx gbfzkqwrbm (qpuryyhlfl, 72 - 82)
Phase 2
20
(CLL/SLL or MCL)
puyqzlnepm(aayhmzzbrd) = kcfgiagdsu hvppfjjqom (snlrytrncv )
Positive
06 Dec 2025
Phase 1
47
llhvlzuklj(sdxichnefx) = akbydwzrqp jalopipukz (kibxecnwmv )
Positive
14 May 2025
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Clinical Trial

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Approval

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Regulation

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