Last update 20 Mar 2025

NP-G2-044

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Target
Action
inhibitors
Mechanism
fascin inhibitors(fascin actin-bundling protein 1 inhibitors)
Active Organization
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC21H16F3N3O2
InChIKeyXLLRLAABUFOJPC-UHFFFAOYSA-N
CAS Registry1807454-59-6

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Esophageal Squamous Cell CarcinomaPhase 2
United States
07 Dec 2021
Non-Muscle Invasive Bladder NeoplasmsPhase 2
United States
07 Dec 2021
Pancreatic Ductal AdenocarcinomaPhase 2
United States
07 Dec 2021
Platinum-Resistant Ovarian CarcinomaPhase 2
United States
07 Dec 2021
Squamous Cell Carcinoma of the OropharynxPhase 2
United States
07 Dec 2021
Triple Negative Breast CancerPhase 2
United States
07 Dec 2021
Liver metastasesDiscovery
United States
03 Nov 2017
metastatic non-small cell lung cancerDiscovery
United States
03 Nov 2017
metastatic non-small cell lung cancerDiscovery
United States
03 Nov 2017
Metastatic Prostate CarcinomaDiscovery
United States
03 Nov 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
45
NP-G2-044 + SOC anti-PD-1 therapy
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Positive
25 Feb 2025
Phase 1
23
(jduxfvxbqe) = fhtlslpycz hvesthiels (qlnwrfquiv )
Positive
20 May 2021
(Ovary + Last Prior Therapy:CSF1R Inhibitor)
dijuucklpt(yxshtaczar) = jwjannkvte ezwmdiprbf (csfkuadrwj )
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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