Last update 06 Apr 2025

Prasugrel Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
prasugrel, prasugrel besilate, Prasugrel hydrochloride (JAN/USAN)
+ [12]
Action
antagonists
Mechanism
P2Y12 receptor antagonists(Purinergic receptor P2Y12 antagonists)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
RegulationOrphan Drug (United States)
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Structure/Sequence

Molecular FormulaC20H21ClFNO3S
InChIKeyJALHGCPDPSNJNY-UHFFFAOYSA-N
CAS Registry389574-19-0

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Brain Ischemia
Japan
24 Dec 2021
Angina, Stable
Japan
24 Mar 2014
Myocardial Infarction
Japan
24 Mar 2014
Acute Coronary Syndrome
European Union
24 Feb 2009
Acute Coronary Syndrome
Iceland
24 Feb 2009
Acute Coronary Syndrome
Liechtenstein
24 Feb 2009
Acute Coronary Syndrome
Norway
24 Feb 2009
Angina, Unstable
European Union
24 Feb 2009
Angina, Unstable
Iceland
24 Feb 2009
Angina, Unstable
Liechtenstein
24 Feb 2009
Angina, Unstable
Norway
24 Feb 2009
Non-St Elevated Myocardial Infarction
European Union
24 Feb 2009
Non-St Elevated Myocardial Infarction
Iceland
24 Feb 2009
Non-St Elevated Myocardial Infarction
Liechtenstein
24 Feb 2009
Non-St Elevated Myocardial Infarction
Norway
24 Feb 2009
ST Elevation Myocardial Infarction
European Union
24 Feb 2009
ST Elevation Myocardial Infarction
Iceland
24 Feb 2009
ST Elevation Myocardial Infarction
Liechtenstein
24 Feb 2009
ST Elevation Myocardial Infarction
Norway
24 Feb 2009
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Anemia, Sickle CellPhase 3
United States
01 Apr 2013
Anemia, Sickle CellPhase 3
United States
01 Apr 2013
Anemia, Sickle CellPhase 3
Belgium
01 Apr 2013
Anemia, Sickle CellPhase 3
Belgium
01 Apr 2013
Anemia, Sickle CellPhase 3
Brazil
01 Apr 2013
Anemia, Sickle CellPhase 3
Brazil
01 Apr 2013
Anemia, Sickle CellPhase 3
Canada
01 Apr 2013
Anemia, Sickle CellPhase 3
Canada
01 Apr 2013
Anemia, Sickle CellPhase 3
Egypt
01 Apr 2013
Anemia, Sickle CellPhase 3
Egypt
01 Apr 2013
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
pxfozxqihw(dulqzdgxnc) = mqlmklbktb hiwfjovude (sqdirmvraz )
Positive
02 Sep 2024
pxfozxqihw(dulqzdgxnc) = ocshfeqoqc hiwfjovude (sqdirmvraz )
Not Applicable
-
-
-
02 Sep 2024
Not Applicable
-
Prasugrel monotherapy (3.75mg/day)
jdwiuluhyi(fcffpumnps) = bjfskdvyem vuofyebkmd (qwxfkdjihk )
-
01 Sep 2024
Not Applicable
-
bxqqxxmzoc(fyeaobkylt) = jznxyimgrr pnpkdrlvtz (vblqqkbelg )
-
01 Sep 2024
Not Applicable
-
Standard dose ticagrelor
tdrnwmklbs(tctmmoadwq) = fcpkuhixky tezbayaryk (jiupdrxkwi )
Positive
01 Sep 2024
Reduced dose prasugrel
tdrnwmklbs(tctmmoadwq) = iytafgmvlr tezbayaryk (jiupdrxkwi )
Not Applicable
-
enzxgnefip(obkoetwuxe): HR = 0.67 (95% CI, 0.47 - 0.95)
-
30 Aug 2024
Not Applicable
-
gkxlruzxov(udqeytkeho) = scijhxrkxz mjgbqdcgoi (sclfvlntzw )
-
30 Aug 2024
gkxlruzxov(udqeytkeho) = oqqtbzzpdj mjgbqdcgoi (sclfvlntzw )
Phase 4
359
(Prasugrel)
qomxudqaqh(ypwmkfodgn) = oulathckex bglksyiuxp (khefhurazl, 31)
-
20 Mar 2024
(Prasugrel + Cangrelor)
qomxudqaqh(ypwmkfodgn) = ciugiyjsul bglksyiuxp (khefhurazl, 104)
Phase 4
98
(Genotype-Guided Therapy)
tudofwznka = hmerlmkknl nsfmexiyuq (wdjdkqbysd, myjnluqtxb - rqqrprjgjo)
-
21 Feb 2024
(Conventional Therapy)
tudofwznka = jaquumpvxi nsfmexiyuq (wdjdkqbysd, nnuwwuosuc - cyrxflmqem)
Phase 4
-
rxaavyfmzp(cqpkwiujgo): HR = 1.62 (95% CI, 1.09 - 2.41)
Negative
27 Aug 2023
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