Last update 21 Sep 2026

BTP0427

Overview

Basic Info

Drug Type
Chemical drugs
Synonyms
BTP 0427, BTP-0427
Target
HCN channels
Action
modulators
Mechanism
HCN channels modulators(Hyperpolarization-activated cyclic nucleotide-gated channel modulators)
Therapeutic Areas
Nervous System DiseasesCardiovascular Diseases
Active Indication
Chronic systolic heart failureReduced ejection fraction co-occurrent and due to chronic heart failureCerebrovascular Disorders
Inactive Indication-
Originator Organization
Beijing Sun-Novo Pharmaceutical Research Co., Ltd.Beijing Sun-Novo Pharmaceutical Research Co., Ltd.
Active Organization
Beijing Baiao Pharmaceuticals Co., Ltd.Beijing Baiao Pharmaceuticals Co., Ltd.Beijing Sun-Novo Pharmaceutical Research Co., Ltd.Beijing Sun-Novo Pharmaceutical Research Co., Ltd.Jiangsu Nuohe Bituo New Drug Research and Development Co., Ltd
Inactive Organization-
License Organization-
Drug Highest PhaseIND Approval
First Approval Date-
Regulation-
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Related

100 Clinical Results associated with BTP0427
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100 Translational Medicine associated with BTP0427
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100 Patents (Medical) associated with BTP0427
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100 Deals associated with BTP0427
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Chronic systolic heart failureIND Approval
China
Beijing Baiao Pharmaceuticals Co., Ltd.Beijing Baiao Pharmaceuticals Co., Ltd.
16 Sep 2026
Chronic systolic heart failureIND Approval
China
Jiangsu Nuohe Bituo New Drug Research and Development Co., Ltd
16 Sep 2026
Reduced ejection fraction co-occurrent and due to chronic heart failureIND Approval
China
Beijing Baiao Pharmaceuticals Co., Ltd.Beijing Baiao Pharmaceuticals Co., Ltd.
16 Sep 2026
Reduced ejection fraction co-occurrent and due to chronic heart failureIND Approval
China
Jiangsu Nuohe Bituo New Drug Research and Development Co., Ltd
16 Sep 2026
Cerebrovascular DisordersPreclinical
China
Beijing Sun-Novo Pharmaceutical Research Co., Ltd.Beijing Sun-Novo Pharmaceutical Research Co., Ltd.
24 May 2024
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Clinical Result

Indication
Phase
Evaluation
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Approval

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Regulation

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