Jiangsu Nuohe Bituo New Drug Research and Development Co., Ltd

Primary purpose: To evaluate the safety and tolerability of single/multiple oral administration of different doses of BTP0209 tablets on an empty stomach in healthy subjects. Secondary purpose: To evaluate the pharmacokinetic characteristics of single/multiple oral administration of different doses of BTP0209 tablets on an empty stomach in healthy subjects and to investigate the effect of food on the pharmacokinetic characteristics of single oral administration of BTP0209 tablets in healthy subjects.

To evaluate the pharmacokinetic characteristics of BTP0611 after single and multiple oral administrations under fasting and high-fat meal conditions, and compare it with ivabradine hydrochloride tablets to compare the differences in pharmacokinetic characteristics, relative bioavailability and safety of single and multiple administrations in healthy adult subjects

Primary objective: To evaluate the safety and tolerability of a single oral dose of BTP0611 (5 mg, 10 mg, 15 mg) in healthy adults; Secondary objective: To evaluate the pharmacokinetic characteristics of a single fasting oral dose of BTP0611 (5 mg, 10 mg, 15 mg) in healthy adults and to investigate the effect of food on the pharmacokinetic characteristics of a single oral dose of BTP0611 (15 mg) in healthy adults.