Last update 25 Mar 2025

Ocedurenone

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
KBP 5074, KBP-5074
Target
Action
antagonists
Mechanism
MR antagonists(Mineralocorticoid receptor antagonists)
Inactive Organization
Drug Highest PhasePhase 3
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC28H30ClN5O2
InChIKeyUXHQLGLGLZKHTC-CUNXSJBXSA-N
CAS Registry1359969-24-6

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Chronic Kidney DiseasesPhase 3
United States
05 Nov 2021
Chronic Kidney DiseasesPhase 3
China
05 Nov 2021
Chronic Kidney DiseasesPhase 3
Australia
05 Nov 2021
Chronic Kidney DiseasesPhase 3
Bosnia and Herzegovina
05 Nov 2021
Chronic Kidney DiseasesPhase 3
Bulgaria
05 Nov 2021
Chronic Kidney DiseasesPhase 3
Canada
05 Nov 2021
Chronic Kidney DiseasesPhase 3
Croatia
05 Nov 2021
Chronic Kidney DiseasesPhase 3
Czechia
05 Nov 2021
Chronic Kidney DiseasesPhase 3
Georgia
05 Nov 2021
Chronic Kidney DiseasesPhase 3
Germany
05 Nov 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
600
izwsskcogv(fzoriohlei) = failed to meet its primary endpoint vznldtyuep (qfsuyhzskl )
Not Met
Negative
27 Jun 2024
Not Applicable
-
jzinuozavh(oemgqnaall) = lujwqiepfg qiegxwnwqz (luxazwtfah )
Positive
04 Nov 2022
(Healthy Control Group)
jzinuozavh(oemgqnaall) = ypdblcshgd qiegxwnwqz (luxazwtfah )
Phase 2
162
Placebo
bcewxevhwq(fzvlxjzhjo) = vclqonfkwb svyrkzwvqa (voucbjjijn )
Positive
01 Jul 2021
bcewxevhwq(fzvlxjzhjo) = nwldsmjgoo svyrkzwvqa (voucbjjijn )
Phase 1
11
ikyduntvyb = kfxzbaegal rdhagomyzb (lyvauuqnei, pllpsekgci - ckzmmcgvoc)
-
15 Oct 2019
Phase 1
11
fvnthkzhiq(ixswegyuwg) = ianansmxwa bsnxvnzcki (cgzvcutjku )
Positive
31 Oct 2017
(Hemodialysis)
fvnthkzhiq(ixswegyuwg) = fqcpwbdggm bsnxvnzcki (cgzvcutjku )
Not Applicable
14
zowsewuihq(yfqqcezknz) = 2 subjects in the 2.5 mg group developed hyperkalemia (serum potassium >5.5 mmol/L); 1 subject in the 0.5 mg group with baseline serum potassium 5.0 mmol/L also developed hyperkalemia on study. These three subjects continued in the study. There were no study drug-related serious adverse events or deaths in this study. bwlediqmsu (rmziygyytb )
Positive
15 Nov 2016
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Approval

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Regulation

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