[Translation] A Phase 3, randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy and safety of the mineralocorticoid receptor antagonist KBP-5074 in subjects with moderate or severe (stage 3b/4) chronic kidney disease (CKD) and uncontrolled hypertension
本研究的主要目的是评估 KBP-5074 在降低收缩压(SBP)方面的有效性和持久性。
本研究的次要目的是:评估 KBP-5074 对舒张压(DBP)和尿白蛋白/肌酐比(UACR)的影响;评估 KBP-5074 的安全性和耐受性。
[Translation] The primary objective of this study is to evaluate the efficacy and durability of KBP-5074 in reducing systolic blood pressure (SBP).
The secondary objectives of this study are: to evaluate the effect of KBP-5074 on diastolic blood pressure (DBP) and urine albumin/creatinine ratio (UACR); and to evaluate the safety and tolerability of KBP-5074.