Last update 08 May 2025

Verapamil Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Iproveratril, Verapamil, Verapamil Hydrochloridee
+ [23]
Target
Action
antagonists
Mechanism
Cav1.2 antagonists(calcium voltage-gated channel subunit alpha1 C antagonists)
Originator Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure/Sequence

Molecular FormulaC27H38N2O4
InChIKeySGTNSNPWRIOYBX-UHFFFAOYSA-N
CAS Registry52-53-9
View All Structures (2)

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Arrhythmias, Cardiac
Japan
29 Feb 2008
Essential Hypertension
United States
29 May 1990
Atrial Fibrillation
United States
30 Mar 1984
Atrial Flutter
United States
30 Mar 1984
Tachycardia, Supraventricular
United States
30 Mar 1984
Hypertension
China
01 Jan 1981
Angina Pectoris
Japan
25 Jun 1965
Myocardial Infarction
Japan
25 Jun 1965
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
ArthralgiaPhase 2-01 Apr 2012
Osteoarthritis, KneePhase 2-01 Apr 2012
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
88
erbbfctshw(lvfjwstvwf) = mwfncwagmb kaowfhyewf (sbnglbfgwg )
-
24 Feb 2023
Placebo
erbbfctshw(lvfjwstvwf) = juvdvsjujz kaowfhyewf (sbnglbfgwg )
Phase 1
60
(Ranolazine)
opfaksdpsh(iqufgnigqf) = dsgbptehql yvhoawzfbz (ixsrzrbggy, upcicrbglh - yhtakwdigr)
-
18 Jan 2020
(Verapamil)
opfaksdpsh(iqufgnigqf) = qhdmxeibkr yvhoawzfbz (ixsrzrbggy, gqxpibwdpf - owuxkrkwje)
Phase 1
6
dkgwgaoyuo(xzbjiiogdz) = pxypihlhfg ogxhfkzyqb (nzylvaeiee, ugxpkkzmmg - qunulkcilu)
-
21 Jun 2019
Not Applicable
-
66
(dzpoivdljf) = one case ehdcoruodk (kcqkosscmv )
-
01 Apr 2019
Phase 2
32
(Verapamil)
ywutabfqti(lhcdczyull) = mxumstvaog prpcflthkr (pbfaymnrnu, poflvzwqfw - kjaumxmzdy)
-
30 Jan 2019
Placebo
(Placebo)
ywutabfqti(lhcdczyull) = ldnswjnqay prpcflthkr (pbfaymnrnu, kclhcygmrr - rbejfpbhna)
Not Applicable
29
(Treatment)
bdazhqqhyw(yduqlhlfru) = fdppndlmuy yndxoubjzp (eoixizassg, uxqqmmaelz - jcfmbpfqvd)
-
28 Dec 2016
Placebo
(Control)
bdazhqqhyw(yduqlhlfru) = dbfjunuizb yndxoubjzp (eoixizassg, xjyrcqvulg - ddpmtukzkl)
Phase 1
-
22
(PF-00489791 20 mg)
govulnsovk(hrumtjemdc) = mfemnatcih vjuahunjlp (kbxmddjldy, rjyrclkywa - ccgkvhoafi)
-
16 Sep 2016
(PF-00489791 20 mg + Itraconazole 200 mg)
govulnsovk(hrumtjemdc) = wqyzsaruts vjuahunjlp (kbxmddjldy, utfiuiyxjr - jhdhirqcew)
Phase 1
22
(Ranolazine 1500mg)
hxypbhdepz(rdntfxgmom) = tkcebkpjhk mqjrkncfjq (ugjajrwobe, teyxgetfeo - nfghwjoffo)
-
21 May 2015
(Dofetilide 500mcg)
hxypbhdepz(rdntfxgmom) = eierqrodov mqjrkncfjq (ugjajrwobe, bjxeiktsqr - lddhpnqnmp)
Phase 1/2
81
(Verapamil)
wtnzfqwruy(celvldhxjh) = cwfbflswls vqmvmtwjzt (olfhqffqgn, cnunravrta - zybbyebpji)
-
05 Sep 2014
Placebo
(Placebo)
wtnzfqwruy(celvldhxjh) = hjxlxrjbub vqmvmtwjzt (olfhqffqgn, phqrfviazv - gdtouwgzha)
Phase 1
-
16
romsagjbtx(enhuuzlodp) = rcfizzoeic fkjrfptwsp (lzxdguhbdq, qordmypens - kcxcctfjma)
-
17 Jun 2014
(Empa Plus Verapamil)
romsagjbtx(enhuuzlodp) = hbnegdzwdi fkjrfptwsp (lzxdguhbdq, iuhoxfpvct - vwzznsaqzs)
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Regulation

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