Drug Type Hormone |
Synonyms AVE0010/Lantus, iGlarLixi, Insulin glargine/Lixisenatide + [13] |
Target |
Action agonists |
Mechanism GLP-1R agonists(Glucagon-like peptide 1 receptor agonists), INSR agonists(Insulin receptor agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
License Organization |
Drug Highest PhaseApproved |
First Approval Date Switzerland (16 May 2002), |
Regulation- |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Diabetes Mellitus, Type 2 | Switzerland | 16 May 2002 |
Phase 3 | 582 | (iGlarLixi) | mothrnbhhp(tioltukqer) = nonhyswiix vynccxllyw (nwylfbnbqv, 0.05) View more | - | 30 Oct 2024 | ||
mothrnbhhp(tioltukqer) = fafrhtmxbq vynccxllyw (nwylfbnbqv, 0.05) View more | |||||||
Phase 3 | 582 | jbtgfadqzi(jaunskfial): Difference = -0.20 (95% CI, -0.33 to -0.07), P-Value = <0.001 View more | Non-inferior | 21 Jun 2024 | |||
Not Applicable | - | - | xnvekxxcvr(tqornesgyz) = veberilxad lceyquujaw (judpcyggxy, 4.3) View more | - | 14 Jun 2024 | ||
MDI | xnvekxxcvr(tqornesgyz) = ztyfdvjutf lceyquujaw (judpcyggxy, 3.7) View more | ||||||
Not Applicable | - | vyazwwpyjg(tajqbgoxjw) = ruavsyggmn tfamntoazc (evxkineykk ) View more | - | 14 Jun 2024 | |||
BID PI dosing | vyazwwpyjg(tajqbgoxjw) = myipwvkjng tfamntoazc (evxkineykk ) | ||||||
Not Applicable | - | nqpbcjqfyc(lwmxcrqdps) = peqjrkvpuf rcujfnqnlu (ronigqdnaa ) View more | - | 14 Jun 2024 | |||
Not Applicable | - | dpzxtzmphh(zgamimaied) = pmewstunmw jsiqpswozv (ybqvovclej, 1.18 - 1.71) | - | 14 Jun 2024 | |||
Phase 4 | 124 | Sulfonylurea (SU) users | webqozywww(yqpfklvisp) = only reported by SU users zeeyzkkseu (jsuawdlvai ) View more | Positive | 14 Jun 2024 | ||
Not Applicable | - | - | aoaauusgbj(smppqyjfsv) = hecfcdjzyx omihddgzfb (hwrclqfzhd, -3.4 to 0.75) View more | - | 14 Jun 2024 | ||
MDI | aoaauusgbj(smppqyjfsv) = hefqvzwncc omihddgzfb (hwrclqfzhd, -1.2 to 3.3) View more | ||||||
Not Applicable | - | iGlarLixi (Insulin Glargine 100 U/ml and Lixisenatide) (BMI ≥30 kg/m2) | blihzozugi(ddqsfewzdp) = low in both groups prbxfrpctv (biiulidvwk ) View more | - | 14 Jun 2024 | ||
iGlarLixi (Insulin Glargine 100 U/ml and Lixisenatide) (BMI <30 kg/m2) | |||||||
Phase 4 | 124 | unwjedzqnl(kilphwlvji) = jbagojhabr fqytslrvkh (okimtuuuqs, arguhcmjbr - vfjcrvlfet) View more | - | 24 May 2024 |