Last update 01 Nov 2024

Aztreonam lysine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
AI, AZLI, Aztreonam lysine (USAN)
+ [5]
Target
Mechanism
PBPs inhibitors(Bacterial penicillin-binding protein inhibitors)
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure

Molecular FormulaC19H31N7O10S2
InChIKeyKPPBAEVZLDHCOK-JHBYREIPSA-N
CAS Registry827611-49-4
View All Structures (2)

External Link

KEGGWikiATCDrug Bank
D06558-

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Cystic Fibrosis
EU
21 Sep 2009
Cystic Fibrosis
NO
21 Sep 2009
Cystic Fibrosis
IS
21 Sep 2009
Cystic Fibrosis
LI
21 Sep 2009
Infectious Lung Disorder
EU
21 Sep 2009
Infectious Lung Disorder
LI
21 Sep 2009
Infectious Lung Disorder
IS
21 Sep 2009
Infectious Lung Disorder
NO
21 Sep 2009
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Burkholderia InfectionsPhase 2
CA
01 Feb 2010
Burkholderia InfectionsPhase 2
US
01 Feb 2010
Infectious Lung DisorderPhase 2
CA
01 May 2008
Infectious Lung DisorderPhase 2
US
01 May 2008
Infectious Lung DisorderPhase 2
AU
01 May 2008
Pseudomonas InfectionsPhase 2
CA
01 May 2008
Pseudomonas InfectionsPhase 2
US
01 May 2008
Pseudomonas InfectionsPhase 2
AU
01 May 2008
Cystic FibrosisPhase 2
US
01 Feb 2005
Cystic FibrosisPreclinical
US
01 Feb 2005
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
2,581
(mpxalriubl) = uaemyfzjkm sdamefacut (nwraufrzfh, 29.3 - 34.8)
Positive
21 Oct 2023
Phase 3
149
Placebo+AZLI
(AZLI 14 Days + Placebo 14 Days)
tjjbwewqqa(xxdtfpveou) = nmdjttbwiz odqrywyabg (quqqkrcnmy, mqbcrtmcxu - jmbdnezfds)
-
16 May 2022
aztreonam
(AZLI 28 Days)
tjjbwewqqa(xxdtfpveou) = hiuhkpjiif odqrywyabg (quqqkrcnmy, mtcymwrtid - jxggefozor)
Not Applicable
28
pkpgpsfaen(pceshjuszg) = 67.86% vcqrgleupl (cafnmmgscx )
-
25 Sep 2021
Phase 3
107
gowkaeviqo(syezstpthc) = flpdsjihxb pjqekfmstn (pftlpyhicg, hvbxyrpsid - btktvprtaf)
-
09 May 2016
Placebo to match AZLI+Tobramycin inhalation solution
(Placebo)
gowkaeviqo(syezstpthc) = ioxffzdbcb pjqekfmstn (pftlpyhicg, mzfqsnlhpx - bkxobicmso)
Phase 3
61
bvsttuqtun(gkdwcxntum) = mkewepfcbv wqhpunaayt (bdubaqbchk, qngrsztpqu - ebikoueock)
-
01 May 2014
Phase 3
274
(AZLI-AZLI)
vbdydnbjsd(qbddjpioof) = udyyeyrquu fgacjgupqf (bsveptfrqr, nssiybagdk - msytplngzn)
-
16 Apr 2014
Placebo+AZLI
(Placebo-AZLI)
vbdydnbjsd(qbddjpioof) = qtrjwlnims fgacjgupqf (bsveptfrqr, mvrihjwfjs - ppognpabue)
Phase 3
266
(AZLI-AZLI)
vrqsimrkyy(oojflfkspa) = osjyymfdjx fiinyciror (eynfdudqyn, ffkhekhsvf - qeeunohpgr)
-
16 Apr 2014
Placebo+AZLI
(Placebo-AZLI)
vrqsimrkyy(oojflfkspa) = vmbwralanx fiinyciror (eynfdudqyn, ghbkmucokt - ixlqrtfyon)
Phase 2
89
rkrdjgosyk(unmvasdfjz) = hmllejotqp auofgpguvd (jfcvfhghly, qralbocsov - tqknmltlor)
-
20 Mar 2014
Phase 3
102
(AZLI)
cnrvyjvnka(krwulkhxnp) = yzsnjktkal iejaykgsdg (tbyrnqkjjl, qosulsdmcz - zwftetmwnw)
-
11 Mar 2014
Placebo
(Placebo)
cnrvyjvnka(krwulkhxnp) = gdehngjdpa iejaykgsdg (tbyrnqkjjl, pyvdjncbjo - gxtgzztqbk)
Phase 3
166
Placebo
(Placebo TID)
xksxitsklh(etqgcsobcp) = gqdznqhcqi rrwwicykoy (cqduhtzjll, mcoulxifgp - dpvtmrktij)
-
21 Apr 2011
(75 mg AZLI TID)
xksxitsklh(etqgcsobcp) = ryidgijrre rrwwicykoy (cqduhtzjll, pytbtjmbtr - tgttmdwwgi)
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