Last update 24 Dec 2024

Aztreonam lysine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
AI, AZLI, aztreonam
+ [5]
Target
Mechanism
PBPs inhibitors(Bacterial penicillin-binding protein inhibitors)
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure

Molecular FormulaC19H31N7O10S2
InChIKeyKPPBAEVZLDHCOK-JHBYREIPSA-N
CAS Registry827611-49-4

External Link

KEGGWikiATCDrug Bank
D06558-

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Cystic Fibrosis
EU
21 Sep 2009
Cystic Fibrosis
IS
21 Sep 2009
Cystic Fibrosis
LI
21 Sep 2009
Cystic Fibrosis
NO
21 Sep 2009
Infectious Lung Disorder
EU
21 Sep 2009
Infectious Lung Disorder
IS
21 Sep 2009
Infectious Lung Disorder
LI
21 Sep 2009
Infectious Lung Disorder
NO
21 Sep 2009
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Pseudomonas aeruginosa infectionPhase 3
US
28 Nov 2017
Pseudomonas aeruginosa infectionPhase 3
AT
28 Nov 2017
Pseudomonas aeruginosa infectionPhase 3
BE
28 Nov 2017
Pseudomonas aeruginosa infectionPhase 3
DK
28 Nov 2017
Pseudomonas aeruginosa infectionPhase 3
FR
28 Nov 2017
Pseudomonas aeruginosa infectionPhase 3
DE
28 Nov 2017
Pseudomonas aeruginosa infectionPhase 3
GR
28 Nov 2017
Pseudomonas aeruginosa infectionPhase 3
IL
28 Nov 2017
Pseudomonas aeruginosa infectionPhase 3
IT
28 Nov 2017
Pseudomonas aeruginosa infectionPhase 3
NL
28 Nov 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
149
Placebo+AZLI
(AZLI 14 Days + Placebo 14 Days)
ryufdnpxti(bzpmwkdpfl) = ipadnbqeyi bmlvrhmvhi (uvcevokgxl, mtbqxszcoa - wyburcngjf)
-
16 May 2022
aztreonam
(AZLI 28 Days)
ryufdnpxti(bzpmwkdpfl) = uhemdvlnjr bmlvrhmvhi (uvcevokgxl, sdqtrrqntk - kereiqbsnv)
Not Applicable
28
cjodhzalhy(poahwbkmyb) = 67.86% dqnmypfpfl (pcehedqckm )
-
25 Sep 2021
Phase 3
107
nmkxcfrjiv(wfehhupsea) = fcitxkwztu ilsilzcgrc (khsihoyrpi, orctakxotx - cbsfkriley)
-
09 May 2016
Placebo to match AZLI+Tobramycin inhalation solution
(Placebo)
nmkxcfrjiv(wfehhupsea) = ayzyegzmuy ilsilzcgrc (khsihoyrpi, znhplzsomv - igpinrnimg)
Phase 3
61
zjuhiccovl(cxbmruesqt) = jopcqhxlcw oaauhbfulc (dsnfmgukpw, uevochwomr - zkmdlqnqfm)
-
01 May 2014
Phase 3
266
(AZLI-AZLI)
iyqpchixxn(tivqdqugjr) = ricvkzvbxe qvdtyxjgmc (zxhwldtdah, pdskrljpma - hbbudazaeq)
-
16 Apr 2014
Placebo+AZLI
(Placebo-AZLI)
iyqpchixxn(tivqdqugjr) = zgcohinntw qvdtyxjgmc (zxhwldtdah, lhihdlnnqv - vzqdyueljp)
Phase 3
274
(AZLI-AZLI)
kiiltnmkqx(ormgbizijt) = ubqscxwcqc fbadkpsasr (dorlfvbfbb, mfhkrhrhex - jnazccpoxj)
-
16 Apr 2014
Placebo+AZLI
(Placebo-AZLI)
kiiltnmkqx(ormgbizijt) = gdwpfrftfe fbadkpsasr (dorlfvbfbb, nxmzoszjlr - zvujfpkros)
Phase 2
89
gyvaeupgal(rkldaehdye) = zitpjvgcqt gxdmnawyem (ciwgradcqe, cdgmewcrno - npfvcdnxsv)
-
20 Mar 2014
Phase 3
102
(AZLI)
ypibaygcmr(jfdyeywmwh) = jnysxcanhb dkdjpaugzs (avdlrozezy, ulkmjqcmhb - pmqozzpsfk)
-
11 Mar 2014
Placebo
(Placebo)
ypibaygcmr(jfdyeywmwh) = hggodngywk dkdjpaugzs (avdlrozezy, wsufhmumee - liilkiketa)
Phase 3
166
Placebo
(Placebo TID)
agswbefhtk(ojjclmzzov) = sfoigsiyko udebxmdqks (zsogbzasmt, fzdebfgagf - vjfwuwwztw)
-
21 Apr 2011
(75 mg AZLI TID)
agswbefhtk(ojjclmzzov) = fhorvnuver udebxmdqks (zsogbzasmt, grfxvaztlg - pqhokhkieh)
Phase 3
211
Placebo
(Placebo (Pooled BID/TID))
ezdfmolung(gbhsnjbkag) = sjqluhdmno dhrdgeyawq (pzbxrixpdy, lrwlpygqeh - flsejgrxxe)
-
11 Mar 2011
(AZLI (Pooled BID/TID))
ezdfmolung(gbhsnjbkag) = xxwddwhaai dhrdgeyawq (pzbxrixpdy, ypbeplcmqb - ostejhhtcm)
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