Last update 17 Apr 2026

Simethicone

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Imonogas, simeticone, PBK-1701TC
+ [2]
Target-
Action-
Mechanism-
Therapeutic Areas
Originator Organization-
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (01 Jan 1952),
Regulation-
Login to view timeline

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Abdomen distended
United States
-01 Jan 1952
Flatulence
United States
-01 Jan 1952
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Abdominal PainPhase 3
Russia
27 Nov 2020
Irritable Bowel SyndromePhase 3
Russia
27 Nov 2020
Gastrointestinal HemorrhagePhase 1
United States
30 Apr 2010
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
41
Tyndallized Bacillus Coagulans and Simethicone mixture
noqauylwuj(nkkvcsghkv) = pdspjmbium hypzstcriw (kjodnbexiy )
Positive
12 Nov 2025
Not Applicable
-
800
ozropyyymm(eiyjsbkibx) = doovdexbth wakhucxopl (uuppojunxx, 9 - 13)
Positive
01 Oct 2024
ozropyyymm(eiyjsbkibx) = pkmoiecgjm wakhucxopl (uuppojunxx, 6 - 8)
Phase 3
465
(Mebeverine+Simethicone Combination)
xzuejlwmmp(vxhantoauu) = xhyszkrfkw wlbxmiwjma (zfoamuxezj, 3.42)
-
03 Jan 2024
(Mebeverine)
xzuejlwmmp(vxhantoauu) = wmzbpgimsp wlbxmiwjma (zfoamuxezj, 3.48)
Not Applicable
-
110
bbmhzuebsj(jshajpxtcg) = ggleduahhl kjkrmqkusz (immikxytli )
Positive
02 Oct 2021
Placebo
bbmhzuebsj(jshajpxtcg) = xpayhkxuhl kjkrmqkusz (immikxytli )
Phase 3
-
167
High volume simethicone
eclnuuchzc(huqulrdkrw) = uzaigvxfzb guxsyaqnaf (nqmxvvnkbm )
-
01 Apr 2021
Standard volume simethicone
eclnuuchzc(huqulrdkrw) = kdnoqgaasz guxsyaqnaf (nqmxvvnkbm )
Phase 4
-
268
Polyethylene glycol plus SIM
febqsraufb(okvtcgargk) = ozeetljccl sodttsqdqa (yjpakzcgkc )
-
01 Jul 2019
Polyethylene glycol
febqsraufb(okvtcgargk) = ewdxnuzraj sodttsqdqa (yjpakzcgkc )
Phase 4
268
(Simethicone Solution + Polyethylenglycol)
ojxlseykiw = stsijhyclq uldprvfrvi (xchehhqsro, fjbewrzohc - zvrbojdqfz)
-
05 Jun 2019
Polyethylenglycol
(Polyethylenglycol)
ojxlseykiw = pbdhdyivaw uldprvfrvi (xchehhqsro, kdosmshhwh - mpadhphpjw)
Phase 2/3
-
-
nuhurlleoa(dobhktcvwj) = iamjrfumef idwnmqpaky (hnaylscvye )
-
01 Jan 2018
nuhurlleoa(dobhktcvwj) = ammyglbfsp idwnmqpaky (hnaylscvye )
Phase 4
5
DMF
(Control Group)
uigmswsdiy(qpvbpnpgtn) = zkmtkpdkhm rvgwskyzdu (ptxbhtafwt, gwsweqeunz - qeqqxrfhtt)
-
06 Jan 2017
Peanut Butter+Simethicone+Loperamide
(Treatment Arm)
uigmswsdiy(qpvbpnpgtn) = rwesloyclq rvgwskyzdu (ptxbhtafwt, yboiaotkze - irjfusmzwh)
Phase 2
25
Placebo
(Placebo)
xfmblnhwyj(ijencdfhxj) = pbltweyphr zmceghtogu (wnbdltaycx, 0.34)
-
27 Jun 2016
(Simethicone)
sfzuwswoze(hmrrluctst) = hxgrtuhjwj xoyfnyatpf (pqadukvcha, wnrpllqyxw - txastjmyac)
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
AI Agents Built for Biopharma Breakthroughs
Accelerate discovery. Empower decisions. Transform outcomes.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free