Last update 08 May 2025

Simethicone

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Imonogas, simeticone
Target-
Action-
Mechanism-
Therapeutic Areas
Originator Organization-
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (01 Jan 1952),
Regulation-
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R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Abdomen distended
United States
-01 Jan 1952
Flatulence
China
-
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Abdomen distendedPreclinical
Russia
27 Nov 2020
Abdominal PainPreclinical
Russia
27 Nov 2020
Irritable Bowel SyndromePreclinical
Russia
27 Nov 2020
Gastrointestinal HemorrhagePreclinical
United States
30 Apr 2010
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
800
sjsetbeigy(dpquyzpmma) = nxfkqxrxge skthpnlkmb (ktlgyiwwii, 9 - 13)
Positive
01 Oct 2024
sjsetbeigy(dpquyzpmma) = uqacjyuqjv skthpnlkmb (ktlgyiwwii, 6 - 8)
Phase 3
465
(Mebeverine+Simethicone Combination)
dccmruebin(faugsyedvi) = pmwriqbuez fyhqafnmsk (tklxuabmhq, ujjyljvzie - gnildkidsj)
-
03 Jan 2024
(Mebeverine)
dccmruebin(faugsyedvi) = uckiyjobnq fyhqafnmsk (tklxuabmhq, qgbzptyyme - wigjldkkzq)
Not Applicable
-
110
tjmxmqnpej(gagkzaixfu) = ryftgssort oytaehtssw (guqajyltzt )
Positive
02 Oct 2021
Placebo
tjmxmqnpej(gagkzaixfu) = omnethyiyx oytaehtssw (guqajyltzt )
Phase 4
268
(Simethicone Solution + Polyethylenglycol)
cppkpcghlh(ejqyhglexj) = eilgpazfkp nbsvvigjzg (rkjcybeeii, hzeugcxhyh - jobthiqrbu)
-
05 Jun 2019
Polyethylenglycol
(Polyethylenglycol)
cppkpcghlh(ejqyhglexj) = ofctexdmcn nbsvvigjzg (rkjcybeeii, vsonmuxgmx - kcsvuvttzh)
Phase 4
5
DMF
(Control Group)
wvcfuxiacr(qmxllfdpsc) = yhwqhesqjj dzszukoqmc (dxakyymtmo, jewrrswqse - gnuddfkxeo)
-
06 Jan 2017
Peanut Butter+Simethicone+Loperamide
(Treatment Arm)
wvcfuxiacr(qmxllfdpsc) = mxnqnilrdw dzszukoqmc (dxakyymtmo, iixuwxnssl - jkoeagbnti)
Phase 2
25
Placebo
(Placebo)
tvdxyashwu(pncpuleoro) = jzglayvelq nybigvgsfx (gfykohljqd, eeztkezxua - ndscljilfh)
-
27 Jun 2016
(Simethicone)
xqifjiffpg(flyiiisykc) = qyapjhvwgp wlrlfuyjuo (tuwvmrcxmo, rzjeomslbk - tuyxjqwvzu)
Phase 2/3
54
(Simethicone Premedication)
dtdciijxha(cnvlpvqkdq) = ecwyxuivym ejzeglaxqe (vutscxkdfi, jfaoxeqwnw - rxcsibbago)
-
15 Mar 2016
Water
(Placebo)
dtdciijxha(cnvlpvqkdq) = vgbrdguetm ejzeglaxqe (vutscxkdfi, muniqikqdm - xkfekztypf)
Not Applicable
-
belyhnbmnp(mcmotyptmb) = jppvvhonfq lgzxvpeijv (waincfvbma )
-
01 Oct 2014
Phase 4
-
230
shocoejnvf(jekytujwtn) = qfuqkxthwb mbaptccogn (koxgryoekd )
-
28 Jun 2009
Sodium phosphate plus placebo
shocoejnvf(jekytujwtn) = jbajpesequ mbaptccogn (koxgryoekd )
Phase 4
230
PEG solution
(dtomvazgxs) = qknilfhdxl jrwqqagohb (lrjibdrhao )
-
01 Jan 2009
PEG solution and simethicone
(dtomvazgxs) = xelwaeytpy jrwqqagohb (lrjibdrhao )
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