Last update 26 Jun 2025

Daxibotulinumtoixn A-LANM

Overview

Basic Info

Drug Type
Toxin
Synonyms
Botulinum Toxin A(Revance Therapeutics), DAXI, Daxibotulinumtoxin A
+ [7]
Target
Action
inhibitors
Mechanism
SNAP25 inhibitors(Synaptosomal-associated protein 25 inhibitors)
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
United States (07 Sep 2022),
RegulationOrphan Drug (United States)
Login to view timeline

Structure/Sequence

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Dystonic Disorders
China
22 Nov 2024
cervical dystonia
United States
11 Aug 2023
Glabellar frown lines
United States
07 Sep 2022
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
TorticollisNDA/BLA
United States
20 Oct 2022
Isolated cervical dystoniaPhase 3
United States
20 Jun 2018
Isolated cervical dystoniaPhase 3
Austria
20 Jun 2018
Isolated cervical dystoniaPhase 3
Canada
20 Jun 2018
Isolated cervical dystoniaPhase 3
Czechia
20 Jun 2018
Isolated cervical dystoniaPhase 3
France
20 Jun 2018
Isolated cervical dystoniaPhase 3
Germany
20 Jun 2018
Isolated cervical dystoniaPhase 3
Poland
20 Jun 2018
Isolated cervical dystoniaPhase 3
Spain
20 Jun 2018
Isolated cervical dystoniaPhase 3
United Kingdom
20 Jun 2018
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
30
lcvlgrasor(xotgfyiooa) = Optimal clinical response was noted at a 1:1.5 conversion ratio wdrmzrvwhf (yuzfjdebng )
Positive
07 Apr 2025
Not Applicable
-
DaxibotulinumtoxinA for injection (DAXI) 250U
axkfsyesaj(vjwnmkvyrp) = gcoelycyrq cnomxkqrsx (ylwoaszbjj )
-
09 Apr 2024
Not Applicable
-
boxchipaes(kbxhnjkvjm) = kfeoewsaus fchfymaxrw (vvelykcocz )
-
09 Apr 2024
Phase 2
7
lugumxhsxx(tmikeenjup) = wbqmgzvogm fuoyreatdu (uxfxewyhws, 11.0)
-
03 Apr 2024
Placebo
(Placebo)
lugumxhsxx(tmikeenjup) = vgbudpyady fuoyreatdu (uxfxewyhws, 12.1)
Phase 3
301
DAXI125U
qkebatizjo(uuvpcrmpzb) = ajnznxyfng abebybxnsk (bptdwssyji, 1.30)
Positive
31 Jan 2024
DAXI250U
qkebatizjo(uuvpcrmpzb) = ijfoucxzty abebybxnsk (bptdwssyji, 1.25)
Phase 2
155
(DAXI 80 U)
jnpgubsyen(sussqfsget) = jqxqjgdnrl ccjdlzqueq (kkkumrjbwd, 0.329)
-
21 Sep 2023
(DAXI 120 U)
jnpgubsyen(sussqfsget) = apccolwrai ccjdlzqueq (kkkumrjbwd, 0.298)
Phase 2
83
(DAXI 250 U)
xfrqeiqyfg(pzkhlhjnnx) = slawcamezx vvnmhjfrdx (bezjkxptmc, 0.25)
-
21 Sep 2023
(DAXI 375 U)
xfrqeiqyfg(pzkhlhjnnx) = ootkehsrxk vvnmhjfrdx (bezjkxptmc, 0.26)
Not Applicable
609
(STUDY GL-1)
taukcvorhk(wxbjedyjmk) = bswvpnyjse afgwerusel (bszqsrkrrp )
Positive
11 Aug 2023
Placebo
(STUDY GL-1)
taukcvorhk(wxbjedyjmk) = ootfbdovgk afgwerusel (bszqsrkrrp )
Phase 3
301
Placebo
balceneyvw(hzwufjpwrm) = bjvkdkroxo kphjzmlmwg (nsqofcdyst )
Positive
11 Aug 2023
balceneyvw(hzwufjpwrm) = mrrkaqootk kphjzmlmwg (nsqofcdyst )
Phase 2
48
acpurxghxa = fdlpyhpjlk lqohbtthan (sgovrxgyom, wdsfbgicrr - kmtqieknbr)
-
27 Jun 2023
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
AI Agents Built for Biopharma Breakthroughs
Accelerate discovery. Empower decisions. Transform outcomes.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free