Last update 21 Nov 2024

Dequalinium Chloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Degualinium Chloride, Dequalinium chloride (JAN/INN), dequalinium chloride vaginal tablets
+ [7]
Target
Mechanism
Enzymes inhibitors, Cell membrane permeability enhancers
Inactive Indication-
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
CN (01 Jan 1996),
Regulation-
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Structure

Molecular FormulaC30H40Cl2N4
InChIKeyLTNZEXKYNRNOGT-UHFFFAOYSA-N
CAS Registry522-51-0

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Candidiasis, Vulvovaginal
CH
29 May 2007
Bacterial Vaginosis
CH
07 May 2007
Stomatitis
CN
01 Jan 1996
Infectious Diseases---
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Bacterial VaginosisPreclinical
CH
01 Jan 2007
Bacterial VaginosisPreclinical
CZ
01 Jan 2007
Bacterial VaginosisPreclinical
SK
01 Jan 2007
Bacterial VaginosisPreclinical
DE
01 Jan 2007
Bacterial VaginosisPreclinical
BE
01 Jan 2007
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
151
(Dequalinium Chloride)
(rhatgysucb) = rlzgronzar quticsabjb (lsggmfeuex, vtiufjuzob - hvickpnlhq)
-
16 Oct 2024
(Metronidazole)
(rhatgysucb) = npxeyhuvla quticsabjb (lsggmfeuex, nsdqtxbqdv - gmgdzekikj)
Not Applicable
Bacterial Vaginosis
First line
premenopausal women
147
ajbiahemyh(htxxvkdhum) = Three patients in the metronidazole group suspended treatment due to an adverse event ngxapzisum (zwpnoxzfax )
Positive
02 May 2024
Phase 4
150
(csrlenxckw): OR = 0.79 (95% CI, 0.56 - 1.1), P-Value = 0.197
-
01 Jan 2021
Clotrimazole 100 mg
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Approval

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Regulation

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