Drug Type Recombinant polypeptide |
Synonyms hPTH-1-34(Eli Lilly), PTH injection(Eli Lilly), Teriparatide injection(Eli Lilly) + [7] |
Target |
Action agonists, stimulants |
Mechanism PTH1R agonists(Parathyroid hormone receptor agonists), Osteogenesis stimulants, Parathyroid hormone replacements |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization |
Drug Highest PhaseApproved |
First Approval Date United States (26 Nov 2002), |
Regulation- |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D06078 | Teriparatide(Eli Lilly) |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Glucocorticoid-induced osteoporosis | Australia | 22 May 2003 | |
Osteoporosis, Postmenopausal | Australia | 22 May 2003 | |
Primary osteoporosis | Australia | 22 May 2003 | |
Osteoporosis | United States | 26 Nov 2002 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Femoral Fractures | Phase 3 | Canada | 01 Jul 2013 | |
Femoral Neck Fractures | Phase 3 | United States | 01 Jan 2012 | |
Femoral Neck Fractures | Phase 3 | Belgium | 01 Jan 2012 | |
Femoral Neck Fractures | Phase 3 | Croatia | 01 Jan 2012 | |
Femoral Neck Fractures | Phase 3 | France | 01 Jan 2012 | |
Femoral Neck Fractures | Phase 3 | Germany | 01 Jan 2012 | |
Femoral Neck Fractures | Phase 3 | Greece | 01 Jan 2012 | |
Femoral Neck Fractures | Phase 3 | Hungary | 01 Jan 2012 | |
Femoral Neck Fractures | Phase 3 | India | 01 Jan 2012 | |
Femoral Neck Fractures | Phase 3 | Netherlands | 01 Jan 2012 |
FDA_CDER Manual | Not Applicable | - | vzcmxjzdve(keuwlbohuh) = yrkllkquge gnjotilsft (ypqnxyxkvy ) View more | Positive | 04 Jun 2024 | ||
Placebo | vzcmxjzdve(keuwlbohuh) = ytcqcmeiwv gnjotilsft (ypqnxyxkvy ) View more | ||||||
FDA_CDER Manual | Not Applicable | 428 | avbjejvyje(bvtfgaiffe) = yokggymlhr htirjgaelp (fomyhznyff ) View more | Positive | 04 Jun 2024 | ||
prednisone or equivalent | - | ||||||
FDA_CDER Manual | Not Applicable | 1,637 | bkbbagbosp(vhnfvdmkjl) = nzngkbfjey ptwxvxzjlg (pawhnbrpwt ) View more | Positive | 04 Jun 2024 | ||
Placebo | bkbbagbosp(vhnfvdmkjl) = lbimckcpog ptwxvxzjlg (pawhnbrpwt ) View more | ||||||
Phase 1 | - | 29 | RT-102/20 µg | jhfjrvgbfe(oswtzgnyvw) = 3- to 4-fold higher compared to the SC injection group oildssryyf (ohohwerfkw ) View more | Positive | 05 Oct 2023 | |
RT-102/80 µg | |||||||
Phase 4 | 37 | (Teriparatide Only) | bwtprjbzuq(ajbwslqovx) = whgsodpbsr namldnkohc (grgwaqbztm, 0.06) View more | - | 02 Aug 2023 | ||
(Denosumab Only) | bwtprjbzuq(ajbwslqovx) = hukhufcktv namldnkohc (grgwaqbztm, 0.01) View more | ||||||
Not Applicable | - | Alendronate 70mg PO weekly | hfadbpktza(mmvfldsvyi) = ukehxepsha kwndfgcgjv (jztjwpglfy ) View more | Positive | 01 Nov 2022 | ||
Not Applicable | - | 25 | hnzcghuhfy(ferinfcgjy) = ilhxqccmqx qgfaugaebd (mvqrfbbdhw, 3.6%) View more | - | 01 Jun 2022 | ||
hnzcghuhfy(ferinfcgjy) = qvoggoouwe qgfaugaebd (mvqrfbbdhw, 3.6%) View more | |||||||
Not Applicable | - | 15 | Teriparatide (group 1) | inppzpfitx(wwiekhzywa) = zifoibrlqd dpmaoaxtil (ceqkdjreed ) View more | Positive | 24 Mar 2022 | |
Teriparatide (group 2) | inppzpfitx(wwiekhzywa) = zuqurjyhji dpmaoaxtil (ceqkdjreed ) View more | ||||||
Not Applicable | 12 | Teriparatide | hjgqfyynih(kpgqqvyplp) = kqxkwsviis wzkxiiwoms (rukfdoytaj ) | Positive | 26 Aug 2021 | ||
Phase 4 | 76 | (Standard Dose Teriparatide) | zrhoheamxy(jsgzdvxgjl) = ocnyxivbzd defrpbadvi (vpshgflwwy, 4.66) View more | - | 22 Jan 2021 | ||
(High Dose Teriparatide) | zrhoheamxy(jsgzdvxgjl) = cforzezvqm defrpbadvi (vpshgflwwy, 5.54) View more |