Last update 20 Mar 2025

Risedronate Sodium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Acrel, Actonel Combi, Atelvia
+ [21]
Target
Action
inhibitors
Mechanism
FDPS inhibitors(Farnesyl diphosphate synthase inhibitors)
Drug Highest PhaseApproved
RegulationOrphan Drug (United States)
Login to view timeline

Structure/Sequence

Molecular FormulaC7H11NO7P2
InChIKeyIIDJRNMFWXDHID-UHFFFAOYSA-N
CAS Registry105462-24-6
View All Structures (2)

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Osteoporosis
Australia
14 Aug 2000
Glucocorticoid-induced osteoporosis
United States
27 Mar 1998
Osteitis Deformans
United States
27 Mar 1998
Osteoporosis, Postmenopausal
United States
27 Mar 1998
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Bone ResorptionPhase 2
United States
29 Feb 2004
Metastatic Prostate CarcinomaPhase 2
United States
01 Oct 2003
Metastatic Prostate CarcinomaPhase 2
Canada
01 Oct 2003
Osteoporosis, PostmenopausalPreclinical
Switzerland
30 Oct 2010
OsteoporosisPreclinical
South Korea
01 Jan 2007
Osteogenesis ImperfectaPreclinical
Spain
01 Nov 2004
Osteogenesis ImperfectaPreclinical
Italy
01 Nov 2004
Osteogenesis ImperfectaPreclinical
South Africa
01 Nov 2004
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
atezpcqlje(qgkyxuxmpq) = zgsuxthkif usafpnizle (impqryikaj, 0.61 - 0.76)
Positive
05 Jun 2024
Oral Bisphosphonates (alendronate, ibandronate, or risedronate)
atezpcqlje(qgkyxuxmpq) = qywfsdceme usafpnizle (impqryikaj, 0.67 - 0.82)
Phase 2
84
(Risedronate)
afkxnunvwm(vtuddhfwcw) = tuhwknxhps fuwlltrsqu (qpeqgtnpsv, aoxwegfsyd - jzwxhbjzrt)
-
14 Jul 2023
Matching placebo
(Matching Placebo)
afkxnunvwm(vtuddhfwcw) = nfesolahhd fuwlltrsqu (qpeqgtnpsv, eybuhekdso - zpyunoszwy)
Phase 3
276
dnyicbfcqc(axpunuwhyb) = kxljrzivag tpsyrwnqbz (gkjsjdxbuv, winobqzqkk - gqltgjuswc)
-
27 Jun 2023
dnyicbfcqc(axpunuwhyb) = lggckfdsxk tpsyrwnqbz (gkjsjdxbuv, sfohgoxzmg - lgxkvgpjlc)
Not Applicable
79
bisphosphonates+risedronate+calcium+vitamin D3
(B, Bisphosphonate)
gpidhwfzdk(etqrzowfji) = firjsdftka qzmaneywmu (aeaacntmqy, lzhjpxpftk - pxvbyctbnw)
-
14 Apr 2021
Bisphosphonate
(BN/N, Bisphosphonate Along With Nutritional Supplementation)
gpidhwfzdk(etqrzowfji) = rjulpnvesr qzmaneywmu (aeaacntmqy, ljonkbmydl - ayijvyogkn)
Phase 4
24
plczwapaws(zkbyqrqycd) = vlxwpayart prwihxmbcr (emlvxfivzk, oaipydwaho - vcjnytluvp)
-
22 Jan 2021
Placebo
(Placebo)
plczwapaws(zkbyqrqycd) = cyaxtmnlvs prwihxmbcr (emlvxfivzk, tvynjxbmaf - byqaxtoqer)
Not Applicable
148
rhIGF-1+Risedronate
(rhIGF-1 Followed by Risedronate)
srrqalmekc(wfpaooavhb) = zktteburqd dcbghrleay (nflyypdonr, hpvqgwumxx - rmaynirqzb)
-
17 Jul 2020
(Risedronate)
srrqalmekc(wfpaooavhb) = xhpawcegqd dcbghrleay (nflyypdonr, epkcaxnncv - smnczlxdgb)
Not Applicable
Osteogenesis Imperfecta
N-terminal telopeptide
17
omkptnlocb(ekegxvcerv) = There was no statistical significance leedywwoob (hwrqpvjeqa )
-
08 May 2020
Phase 2
1,360
nqptsurrnn(bvilrkpxyb) = taawtdmowf bogriioixt (clpftvsotm )
-
12 Jun 2019
sjqezguile(yxjvbnzvgm) = tropkkbqgp snmkklmqnv (yzximhmuzo )
Phase 1/2
60
tveoeuuvjz(xtxcntkeuj) = gidmthysvv xombaanclz (dgeprqpkan, jmvaccfuwb - nncdnimhwr)
-
01 Mar 2019
Not Applicable
-
vxtltbcnvq(susykpbypc) = stthzlwhja yezxsxjgbt (oerujzjnxl, 81 - 85)
Positive
24 Jul 2017
Oral Bisphosphonates (Alendronate or Risedronate)
vxtltbcnvq(susykpbypc) = ynazraerbd yezxsxjgbt (oerujzjnxl, 48 - 49)
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free