Last update 29 Nov 2024

ZGGS18

Overview

Basic Info

Drug Type
Antibody fusion proteins
Synonyms
ZGGS 18, ZGGS-18
Target
TGF-β x VEGF
Mechanism
TGF-β inhibitors(Transforming growth factor beta inhibitors), VEGF inhibitors(Vascular endothelial growth factor inhibitors)
Therapeutic Areas
Neoplasms
Active Indication
Advanced Malignant Solid NeoplasmSolid tumor
Inactive Indication-
Originator Organization
Suzhou Zelgen Biopharmaceuticals Co., Ltd.Suzhou Zelgen Biopharmaceuticals Co., Ltd.
Active Organization
Suzhou Zelgen Biopharmaceuticals Co., Ltd.Suzhou Zelgen Biopharmaceuticals Co., Ltd.
Inactive Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with ZGGS18
NCT05584800 / RecruitingPhase 1/2
A Phase I/II Dose Escalation, Tolerability, Safety, Pharmacokinetics and Multiple Cohort Expansion Study of ZGGS18 in Patients With Advanced Solid Tumors
CTR20222300 / RecruitingPhase 1/2
ZGGS18在晚期实体瘤患者中的剂量递增、耐受性、安全性、药代动力学和多队列扩展的I/II期临床研究
[Translation] A Phase I/II clinical study of dose escalation, tolerability, safety, pharmacokinetics and multi-cohort expansion of ZGGS18 in patients with advanced solid tumors
100 Clinical Results associated with ZGGS18
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100 Translational Medicine associated with ZGGS18
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100 Patents (Medical) associated with ZGGS18
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100 Deals associated with ZGGS18
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 2
CN
Suzhou Zelgen Biopharmaceuticals Co., Ltd.Suzhou Zelgen Biopharmaceuticals Co., Ltd.
09 Nov 2022
Solid tumorPhase 1
US
Suzhou Zelgen Biopharmaceuticals Co., Ltd.Suzhou Zelgen Biopharmaceuticals Co., Ltd.
26 Jul 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
NCT05584800 (ASCO2024)
ManualManual
Phase 1
Advanced Malignant Solid Neoplasm
21
seardaaslr(egrtvpmnwt) = cynuehimfm epdrxjnthd (xlleqntvok )
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Positive
24 May 2024
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Approval

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Regulation

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