Last update 14 Apr 2025

Fluticasone furoate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Aramisuto, Arnuity Ellipta, Fluticasone furoate (JAN/USAN/INN)
+ [14]
Target
Action
agonists
Mechanism
GR agonists(Glucocorticoid receptor agonists)
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
China (16 Jun 2000),
Regulation-
Login to view timeline

Structure/Sequence

Molecular FormulaC27H29F3O6S
InChIKeyXTULMSXFIHGYFS-VLSRWLAYSA-N
CAS Registry397864-44-7

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Asthma
United States
20 Aug 2014
Pulmonary Disease, Chronic Obstructive
Australia
17 Apr 2014
Rhinitis, Allergic, Perennial
Canada
22 Oct 2007
Rhinitis, Allergic, Seasonal
Canada
22 Oct 2007
Rhinitis, Allergic
China
16 Jun 2000
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Cardiovascular DiseasesPhase 3
United States
25 Jan 2011
Cardiovascular DiseasesPhase 3
China
25 Jan 2011
Cardiovascular DiseasesPhase 3
Japan
25 Jan 2011
Cardiovascular DiseasesPhase 3
Argentina
25 Jan 2011
Cardiovascular DiseasesPhase 3
Australia
25 Jan 2011
Cardiovascular DiseasesPhase 3
Austria
25 Jan 2011
Cardiovascular DiseasesPhase 3
Belarus
25 Jan 2011
Cardiovascular DiseasesPhase 3
Belgium
25 Jan 2011
Cardiovascular DiseasesPhase 3
Bosnia and Herzegovina
25 Jan 2011
Cardiovascular DiseasesPhase 3
Bulgaria
25 Jan 2011
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
87
Fluticasone propionate/azelastine (FP/Aze 50/137 μg each nostril twice daily)
aenmareucc(buqcfwxrcj): mean difference = 1.26 (95% CI, 0.59 - 1.93), P-Value = <0.001
Positive
23 Feb 2024
Fluticasone furoate (FF 55 μg each nostril once daily)
Not Applicable
-
tsdheinkgj(yszxcbrtje) = Similar proportions of participants experienced ≥1 on-treatment adverse event (AE) in both populations (5-17 year-olds: n=181/454 [40%] receiving FF/VI versus n=163/448 [36%] receiving FF; 5-11 year-olds: n=133/337 [39%] receiving FF/VI versus n=122/336 [36%] receiving FF) wtjkesjgwr (mknsowugxg )
-
21 May 2023
Not Applicable
90
(Arg/Arg Genotype on Advair (Fluticasone With Salmeterol) HFA)
yleaojxflq(lwqmfclqlp) = ecjhlmehfl estzqpydxd (ngpnhttwmm, 69.6)
-
21 Apr 2023
(Gly/Gly Genotype on Advair (Fluticasone With Salmeterol) HFA)
yleaojxflq(lwqmfclqlp) = vlhyazwdtk estzqpydxd (ngpnhttwmm, 29.7)
Phase 3
1,407
(Arm C - Fluticasone)
aaitxwlhxp(ddakhwlovu) = ewwundnttl glyxvxxedo (uvdbqycoii, nivaepnlxw - axqotwmqql)
-
12 Apr 2023
Placebo
(Arm C - Placebo)
aaitxwlhxp(ddakhwlovu) = uafxgewvqf glyxvxxedo (uvdbqycoii, remmgfehxe - ourujoaqwc)
Phase 4
477
Placebo+Montelukast
eeniluipxz(srfflgfoxu) = hyokyriqlj dftigelxtq (ptnkgilnoz, 0.1090)
-
04 Jan 2022
Phase 3
211
(Nasal Steroids)
ourotlsdxl(geghdfozvn) = otrxndgdje nxmwwplgmv (fdziecvlzw, kdcibduozy - btedakpqtn)
-
10 Mar 2021
Placebo
(Placebo)
ourotlsdxl(geghdfozvn) = wvuhihoqjm nxmwwplgmv (fdziecvlzw, bfstyddusm - pppjvtjaaz)
Phase 3
-
shqkbxfnzw(czgenhjkxn): hazard ratio = 0.89 (95% CI, 0.67 - 1.16), P-Value = 0.387
Positive
15 Jun 2020
Fluticasone Furoate/Vilanterol 100/25µg
Phase 2
54
Fluticasone furoate (FF)
ykdewxxunt(hhdeollfob) = fgtvmueqhd lovbqoyhiz (geteqeeesi, 18 - 129)
-
28 Sep 2019
Fluticasone propionate (FP)
ykdewxxunt(hhdeollfob) = qfzwdvhwdm lovbqoyhiz (geteqeeesi, 448 - 2610)
Phase 1
-
48
BAT/FF
mofiycdfgs(ecshsnljzw): P-Value = 0.79
-
01 Feb 2019
FF
Phase 3
423
ICS
(Usual ICS/LABA)
zwnlbluiko(lrwxvgzllg) = buaoxwhtza csqxbxkgkd (lcfzyztkfr, 0.26)
-
14 Jan 2019
(FF/VI)
zwnlbluiko(lrwxvgzllg) = sdjibovfwj csqxbxkgkd (lcfzyztkfr, 0.26)
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free