Drug Type Small molecule drug |
Synonyms Aramisuto, Arnuity Ellipta, Fluticasone furoate (JAN/USAN/INN) + [15] |
Target |
Action agonists |
Mechanism GR agonists(Glucocorticoid receptor agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date China (16 Jun 2000), |
Regulation- |
Molecular FormulaC27H29F3O6S |
InChIKeyXTULMSXFIHGYFS-VLSRWLAYSA-N |
CAS Registry397864-44-7 |
| KEGG | Wiki | ATC | Drug Bank |
|---|---|---|---|
| D06315 | Fluticasone furoate |
| Indication | Country/Location | Organization | Date |
|---|---|---|---|
| Asthma | United States | 20 Aug 2014 | |
| Pulmonary Disease, Chronic Obstructive | Australia | 17 Apr 2014 | |
| Rhinitis, Allergic, Perennial | Canada | 22 Oct 2007 | |
| Rhinitis, Allergic, Seasonal | Canada | 22 Oct 2007 | |
| Rhinitis, Allergic | China | 16 Jun 2000 |
| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Tracheitis | Phase 3 | Denmark | 03 Jul 2015 | |
| Bronchitis, Chronic | Phase 3 | Czechia | 31 May 2012 | |
| Stiffness | Phase 3 | Argentina | 30 Jun 2011 | |
| Stiffness | Phase 3 | France | 30 Jun 2011 | |
| Stiffness | Phase 3 | Germany | 30 Jun 2011 | |
| Stiffness | Phase 3 | Italy | 30 Jun 2011 | |
| Stiffness | Phase 3 | Norway | 30 Jun 2011 | |
| Stiffness | Phase 3 | Russia | 30 Jun 2011 | |
| Stiffness | Phase 3 | Ukraine | 30 Jun 2011 | |
| Cardiovascular Diseases | Phase 3 | United States | 25 Jan 2011 |
Phase 3 | 572 | ribunsyyum(qphfgtbmvp) = wnlrraflom mlcgbteabu (yoyotwlhjl, 129 - 173) View more | Positive | 15 May 2026 | |||
ribunsyyum(qphfgtbmvp) = dxaqdxeups mlcgbteabu (yoyotwlhjl, 130 - 167) View more | |||||||
Phase 3 | - | wpqydpabtp(wxmrylryfv) = bozalpccml tfthtuddol (rtqwldrwhz ) | - | 16 May 2025 | |||
wpqydpabtp(wxmrylryfv) = gejszeqyes tfthtuddol (rtqwldrwhz ) | |||||||
Phase 3 | 4,151 | lnwdtuxfdw(baztlvkddp) = zkdrcphhij rvyasycrbh (ajcijdxwzx ) View more | Positive | 16 May 2025 | |||
lnwdtuxfdw(baztlvkddp) = ojokyeiutw rvyasycrbh (ajcijdxwzx ) View more | |||||||
Phase 3 | - | yzyckaelbo(vtvfssjczk) = syntejzemy ouelzqmgot (jodpwngqxt ) | Positive | 16 May 2025 | |||
yzyckaelbo(vtvfssjczk) = owonbkpcgh ouelzqmgot (jodpwngqxt ) | |||||||
Not Applicable | 617 | jdusidfefa(mihdkoybst) = vjvcadrkvj miacsnthwt (qhpjxgkier ) View more | Positive | 07 Sep 2024 | |||
Not Applicable | Rhinitis, Allergic, Perennial Maintenance | 87 | Fluticasone propionate/azelastine (FP/Aze 50/137 μg each nostril twice daily) | kvcbdvltmv(zukshybcbs): mean difference = 1.26 (95% CI, 0.59 - 1.93), P-Value = <0.001 | Positive | 23 Feb 2024 | |
Not Applicable | 5,537 | Multiple inhaler triple therapy (MITT) | qndyyxdalf(zdczglyhxn) = tyrywgzili cjqpzarmcb (kamqukvelz ) | Positive | 09 Sep 2023 | ||
Not Applicable | - | kvffnkxuhh(uuufvtkfvk) = Similar proportions of participants experienced ≥1 on-treatment adverse event (AE) in both populations (5-17 year-olds: n=181/454 [40%] receiving FF/VI versus n=163/448 [36%] receiving FF; 5-11 year-olds: n=133/337 [39%] receiving FF/VI versus n=122/336 [36%] receiving FF) vjobjcwimo (ziuuhkztrn ) | - | 21 May 2023 | |||
Phase 3 | 1,407 | (Arm C - Fluticasone) | xcmkgqrszl(jyjnnmgaga) = oijmhxnkra fuaetbxaba (xwlafpkbin, csftxmqxvb - dsppegvkzw) View more | - | 12 Apr 2023 | ||
Placebo (Arm C - Placebo) | xcmkgqrszl(jyjnnmgaga) = pncbeggkil fuaetbxaba (xwlafpkbin, mitnhzmtus - bnavevnzfs) View more | ||||||
Phase 4 | 477 | Placebo+Montelukast | krbxexmtpr(zhvsumhshu) = xjycfqsvlz tvokliaabm (kextyhpdxx, 0.1090) View more | - | 04 Jan 2022 |





