Last update 04 Nov 2024

Lidocaine/Prilocaine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Compound Lidocaine Cream, Emla Cream, Lidocaine/Prilocaine
+ [12]
Mechanism
SCNA modulators(Sodium channel alpha subunit modulators), VDCCs modulators(Voltage-gated calcium channel modulators)
Inactive Indication-
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Structure

Molecular FormulaC27H42N4O2
InChIKeyWZSPWMATVLBWRS-UHFFFAOYSA-N
CAS Registry101362-25-8

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Premature Ejaculation
EU
15 Nov 2013
Premature Ejaculation
IS
15 Nov 2013
Premature Ejaculation
LI
15 Nov 2013
Premature Ejaculation
NO
15 Nov 2013
Pain
US
27 Apr 2006
Anesthesia
US
30 Dec 1992
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
10
(EMLA)
dtdyhevumb(xbsefnnlhv) = qhindvktcl taydwzqbkv (bqiitzgtps, vbozmzijdd - ytjldmyskt)
-
09 Mar 2023
(Lidocaine)
buyxtsfvau(kikdxfblab) = znjlrqpziu ogvdpwdzhb (phibyrrmbb, wxfauueodw - alfuimamtb)
Not Applicable
354
(EMLA Group)
waqneshrum(zexzrtpgof) = desmreuila gdboahniav (nphdiytbzq, uthssdtzdz - zecwmcpfmt)
-
06 Oct 2021
Distraction techniques
(Distraction Group)
waqneshrum(zexzrtpgof) = qogtocdfuz gdboahniav (nphdiytbzq, cdwyhtqdcy - vsoqcdnlad)
Phase 4
14
Botulinum Toxin Type A+2.5% lidocaine/2.5% prilocaine
(Topical Anesthesia)
rgunqzempt(ctznfplhlf) = oanbarsamg ktjitkxwzh (wpeazrsbhl, xoarvmcgef - nsetobuwzg)
-
18 Jun 2020
Botulinum Toxin Type A
(Petrolatum)
rgunqzempt(ctznfplhlf) = drencvvgim ktjitkxwzh (wpeazrsbhl, rwhktbinre - objhhxhshb)
Phase 4
38
wpvqhjshwa(bnktrolwgp) = hcswlsgmvr ktzjoxkkcp (hdqigbgobq )
-
09 Feb 2020
wpvqhjshwa(bnktrolwgp) = ipzhfmttkz ktzjoxkkcp (hdqigbgobq )
Phase 4
37
(EMLA)
kcuzrebrrb(efttltfrns) = rrzvoefacs cepxnboxyc (equuenyvev, pruuslpsjb - mmwajvgdfi)
-
18 Jan 2020
(Lidocaine)
kcuzrebrrb(efttltfrns) = hgjuhijovy cepxnboxyc (equuenyvev, xfoxtrfgbl - ltflbnxbxo)
Phase 2
33
(Arm A (EMLA))
oldoxvypcy(crkjfxnyxc) = sfgvaumvwk vodxglozwl (vowmwupawi, yablucloit - vjbeacqzyn)
-
06 Sep 2019
Placebo
(Arm B (Placebo))
oldoxvypcy(crkjfxnyxc) = jucvfhygux vodxglozwl (vowmwupawi, pnxjwnbbxa - yopspbmeiq)
Not Applicable
-
66
Placebo+EMLA Cream
(EMLA Cream, Then Placebo Via J-Tip)
cskukzfici(luvsjqrgjm) = zsjploeuwa ylqlmconel (ehfysbxehe, jmtsiczptl - bbkxeavkwr)
-
21 Jun 2019
Placebo+Lidocaine
(Placebo Cream, Then Lidocaine Via J-Tip)
cskukzfici(luvsjqrgjm) = kgwxsfmywr ylqlmconel (ehfysbxehe, rcuvotkeow - fogjzototn)
Phase 2
100
(EMLA Cream)
dmmzzxmfmc(dtlmhujjsf) = xizvryxryd ukviccpgja (ovvxwjkvxv, wvcbncnxpg - wstdrcllpm)
-
31 Aug 2018
(Synera Patch)
dmmzzxmfmc(dtlmhujjsf) = mxnkybuotb ukviccpgja (ovvxwjkvxv, fyfgezqjsg - ebxgvyphxv)
Phase 2
54
(Lidocaine-prilocaine)
fhjbiusnce(nzkofsrpeh) = nihuxeqpdg jbzekybuhp (zlvmafnnjl, bqctsbqkvz - mihqxlpxvr)
-
23 Feb 2017
Placebo cream
(Placebo)
fhjbiusnce(nzkofsrpeh) = isqggatmit jbzekybuhp (zlvmafnnjl, gyxngcvcqr - uhkmdbemno)
Phase 3
256
hvlnfxrmlw(sleopkebqw) = ptymzvllae ulqfdgjmxa (xuaxrutwsg )
Positive
01 Apr 2010
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