Last update 01 Nov 2024
Amlodipine Besylate/Azilsartan/Hydrochlorothiazide
Last update 01 Nov 2024
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms Amlodipine/azilsartan/hydrochlorothiazide, Amlodipine/hydrochlorothiazide/azilsartan, Azilsartan/amlodipine/hydrochlorothiazide + [5] |
Mechanism AT1R antagonists(Angiotensin II Receptor Type 1 antagonists), CYP1A2 inhibitors(Cytochrome P450 1A2 inhibitors), NCC inhibitors(Thiazide-sensitive sodium-chloride cotransporter inhibitors) + [1] |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedNDA/BLA |
First Approval Date- |
Regulation- |
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Structure
Molecular FormulaC26H31ClN2O8S |
InChIKeyZPBWCRDSRKPIDG-UHFFFAOYSA-N |
CAS Registry111470-99-6 |
View All Structures (3)
Related
3
Clinical Trials associated with Amlodipine Besylate/Azilsartan/HydrochlorothiazideA Phase 1, Randomized, Open-Label, Crossover Study to Evaluate the Food-Effect of Single Oral Dose Administration of TAK-536TCH Final Formulation Tablet in Healthy Adult Male Subjects
A Phase 1, Randomized, Open-Label, Crossover Study to Evaluate the Food-Effect of Single Oral Dose of TAK-536TCH Final Formulation Tablet in Healthy Adult Male Subjects
A Phase 3, Open-label, Multicenter, Long-term Study to Evaluate the Safety and Efficacy of TAK-536, Amlodipine and Hydrochlorothiazide in Subjects With Essential Hypertension
100 Clinical Results associated with Amlodipine Besylate/Azilsartan/Hydrochlorothiazide
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100 Translational Medicine associated with Amlodipine Besylate/Azilsartan/Hydrochlorothiazide
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100 Patents (Medical) associated with Amlodipine Besylate/Azilsartan/Hydrochlorothiazide
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100 Deals associated with Amlodipine Besylate/Azilsartan/Hydrochlorothiazide
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Essential Hypertension | NDA/BLA | JP | - |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
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Phase 3 | 341 | (pllilqzzhi) = njewbeqphv rleosjciwd (gockvqkmcd, sufnsdhfwi - xpjylcidgu) View more | - | 26 Jun 2017 | |||
Phase 1 | 12 | (TAK-536TCH Fasted) | mxpzufqwlr(oefbyzfcys) = stneoucwxy zokhysskyp (gmtkdsakwz, cghphcucmb - mihmgxncgz) View more | - | 26 Apr 2016 | ||
(TAK-536TCH Fed) | mxpzufqwlr(oefbyzfcys) = cxtbdxgqnj zokhysskyp (gmtkdsakwz, rvkwlthcue - xtualcipvd) View more |
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