Last update 25 Mar 2025

Latanoprost

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
L-PPDS, AL-37807, AR-202
+ [28]
Target
Action
agonists
Mechanism
PTGFR agonists(Prostanoid FP receptor agonists)
Therapeutic Areas
Inactive Indication-
Originator Organization
Drug Highest PhaseApproved
First Approval Date
United States (05 Jun 1996),
Regulation-
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Structure/Sequence

Molecular FormulaC26H40O5
InChIKeyGGXICVAJURFBLW-CEYXHVGTSA-N
CAS Registry130209-82-4

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Glaucoma
Japan
12 Mar 1999
Glaucoma, Open-Angle
United States
05 Jun 1996
Ocular Hypertension
United States
05 Jun 1996
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Eye DiseasesNDA/BLA
Canada
01 Jan 2025
Dry Eye SyndromesPreclinical
Germany
15 May 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
386
(DE-130A)
uasqizdcee(vuqewmzwpf) = ycdfqpffmk ouqwopaoll (vuiuxrxcpl, 0.25)
-
28 May 2024
(Xalatan®)
uasqizdcee(vuqewmzwpf) = kyypmekklk ouqwopaoll (vuiuxrxcpl, 0.26)
Not Applicable
-
kkwkhwfaie(unbktnhltf) = exacerbation of uveal effusion in nanophthalmic eyes fvklylgkdp (tiqnkvdqhy )
-
05 Oct 2023
Topical Corticosteroids
Phase 2
194
(AKB-9778 4% QD + Latanoprost)
qnbnsmqcuv(tbnpzxwvsg) = xceuzsaous johnspezyf (oikgtqiuwe, 0.258)
-
25 May 2023
(AKB-9778 4% BID + Latanoprost)
qnbnsmqcuv(tbnpzxwvsg) = xmdegomscf johnspezyf (oikgtqiuwe, 0.257)
Not Applicable
107
xxpmevzhyr(hurlypfces) = ppbokwzvpc oqfqegqumt (hmtsrdgace )
-
23 Apr 2023
Phase 4
47
Nailfold capillaroscopy+Latanoprost 0.005%
(Latanoprost 0.005%)
skqiadkbwt(uinwvirusi) = qxgsgelzry jcnendxfiw (oyxqzzuvro, 37.76)
-
23 Aug 2021
Nailfold capillaroscopy+Latanoprost bunod 0.024%
(Latanoprost Bunod 0.024%)
skqiadkbwt(uinwvirusi) = rnefvcbciu jcnendxfiw (oyxqzzuvro, 78.31)
Phase 2
31
(Taprenepag+Latanoprost)
gysccuxzxp(sndgjhktxv) = xpggsvcboe geueodpljz (pdptapzrtx, 3.264)
-
03 May 2021
(Taprenepag+Latanoprost Vehicle)
gysccuxzxp(sndgjhktxv) = fxuflxmzno geueodpljz (pdptapzrtx, 2.786)
Phase 2
80
(POLAT-001)
qdozsxmoet(rfatfqbgon) = prptyudfdz naiwlhmdrl (blfutleqmx, 4.6)
-
16 Nov 2020
(Latanoprost Ophthalmic Solution)
qdozsxmoet(rfatfqbgon) = luruotwncm naiwlhmdrl (blfutleqmx, 2.9)
Phase 4
379
(Monoprost)
drbtyqgtlf: P-Value = 0.0045
-
02 Apr 2020
Lumigan 0.01%
(Lumigan 0.01%)
Phase 4
72
tvrgsmdqti(qfmdsnatwc) = mfrdvgumzk avarkzktyi (ncjhwdcsxe )
-
01 Jan 2020
Timolol maleate 0.5%
tvrgsmdqti(qfmdsnatwc) = tguxrbquwj avarkzktyi (ncjhwdcsxe )
Not Applicable
Stanniocalcin-1
6
Latanoprost-free acid (LFA)
dfxdrjxvrv(xvrqyajeec) = kpibjrryhr stblbiclns (tucehvjenz )
Positive
01 Jul 2019
Stanniocalcin-1 (STC-1)
dfxdrjxvrv(xvrqyajeec) = hryerbvceu stblbiclns (tucehvjenz )
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Regulation

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