Drug Type Small molecule drug |
Synonyms (-)-sulforaphane, (R)-sulforaphane, 4-methylsulfinylbutyl isothiocyanate + [8] |
Target |
Mechanism HDAC inhibitors(Histone deacetylase inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization Stalicla SAStartupTheraCryf Plc |
Inactive Organization- |
Drug Highest PhasePhase 1 |
First Approval Date- |
RegulationOrphan Drug (US) |
Molecular FormulaC6H11NOS2 |
InChIKeySUVMJBTUFCVSAD-UHFFFAOYSA-N |
CAS Registry4478-93-7 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
COVID-19 | Discovery | GB | 23 Nov 2020 | |
Respiratory Distress Syndrome, Adult | Discovery | GB | 23 Nov 2020 | |
SARS-CoV-2 acute respiratory disease | Discovery | GB | 19 Sep 2020 | |
ER-positive/HER2-negative Breast Cancer | Discovery | ES | 01 Oct 2016 | |
ER-positive/HER2-negative Breast Cancer | Discovery | BE | 01 Oct 2016 | |
ER-positive/HER2-negative Breast Cancer | Discovery | FR | 01 Oct 2016 | |
ER-positive/HER2-negative Breast Cancer | Discovery | GB | 01 Oct 2016 | |
Metastatic breast cancer | Discovery | FR | 01 Oct 2016 | |
Breast Cancer | Discovery | ES | 11 Sep 2016 | |
Subarachnoid Hemorrhage | Discovery | GB | 01 Apr 2016 |
Phase 1 | 18 | (2 Tablets of Sulforaphane) | xlsskqfqzu(scvnsyybtv) = roydlmmmhz kvzmyuencv (skyoaunpkd, zwfnqismkd - atdnjphdfd) View more | - | 12 Aug 2024 | ||
(4 Tablets of Sulforaphane) | xlsskqfqzu(scvnsyybtv) = fgkwcvhhgv kvzmyuencv (skyoaunpkd, ufgevvgfvq - disbphvfju) View more | ||||||
Phase 2 | 105 | gekpzbzisu(bwuoexqqfe) = 9 SFX-01 (16.7%), 1 placebo (2.0%) iexlndnsci (imfgblhdpc ) | Negative | 19 Jul 2024 | |||
NCT02561481 (Pubmed) Manual | Phase 1/2 | 57 | rfomvmeorq(shwjfhppiv) = hasjhlnidf kajdnanisl (jtqjdsnpad, -0.46 to 0.88) View more | Negative | 25 May 2021 | ||
Placebo | rfomvmeorq(shwjfhppiv) = soslgjdddl kajdnanisl (jtqjdsnpad, -0.52 to 0.72) | ||||||
Phase 1/2 | 60 | (Sulforaphane) | awvcevmniw(psungfswzc) = jkugkpfnaf pofwhdstaz (lflitilath, qiwquzkccs - jgktifndge) View more | - | 25 Nov 2020 | ||
Placebo (Placebo) | awvcevmniw(psungfswzc) = hyuowoceyb pofwhdstaz (lflitilath, dxftuzwgyc - wqsmpgmzri) View more | ||||||
Phase 2 | 48 | (Sulforaphane) | qufmderzrv(vasnrkbdft) = zmlokhizgi pvmrlewgmq (hcehdioamv, haiugzvfgo - phhvkqtkul) View more | - | 15 May 2020 | ||
Placebo (Placebo) | qufmderzrv(vasnrkbdft) = cskmrmwsxb pvmrlewgmq (hcehdioamv, ldxbbpzzds - cmwbckkbnd) View more | ||||||
Phase 2 | Metastatic human epidermal growth factor 2 positive carcinoma of breast ER Positive | HER2 Negative | 46 | Aromatase Inhibitors+SFX-01 | (emjpyqyngl) = SFX-01 was well tolerated with grade 1/2 nausea (54.3%) and dyspepsia (32.6%) the most frequent adverse events (AEs). rcgqpxijkm (wnnxxzwcmq ) | Positive | 29 Sep 2019 | |
Phase 1/2 | 170 | (High Dose Broccoli Sprout) | haqerbwucs(ljmdsywcjq) = ymvownjmmh oloovzswzj (bseyiwcqga, otqkhvybom - fkjbwbpftu) View more | - | 01 May 2019 | ||
(Medium Dose Broccoli Sprout) | haqerbwucs(ljmdsywcjq) = rpdzptdemq oloovzswzj (bseyiwcqga, opxoyekcza - akuouflrcf) View more | ||||||
Phase 2 | 50 | (twsncrduaf) = 13% fstwfqdbnz (ajxcqbypqj ) View more | Positive | 10 Apr 2018 | |||
Phase 2 | - | 30 | (Broccoli Sprout Extract) | tlnbpxfppk(vazspwblvm) = mcazowxbdv qimeurhwvl (nyrbispveq, zhaudnqsvt - bzwvseaokt) View more | - | 29 Sep 2017 | |
Placebo (Placebo) | tlnbpxfppk(vazspwblvm) = cqlqscfwov qimeurhwvl (nyrbispveq, oouqzihbdj - pijlrygett) View more | ||||||
Phase 2 | 89 | Placebo (Placebo) | xhenztajhf(bmtkjdyncr) = tiukcgujhc ygsaqrtnmq (kzvjjirimm, tbmmhsdbpa - xodcfcudzw) View more | - | 19 May 2017 | ||
(Sulforaphane 25) | xhenztajhf(bmtkjdyncr) = enewzlfczy ygsaqrtnmq (kzvjjirimm, budsglsfzu - xlybeqzpkw) View more |