Last update 09 Jul 2025

Sulforadex

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(-)-sulforaphane, (R)-sulforaphane, 4-methylsulfinylbutyl isothiocyanate
+ [9]
Target
Action
inhibitors
Mechanism
HDAC inhibitors(Histone deacetylase inhibitors), Epigenetic drug
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
RegulationOrphan Drug (United States)
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Structure/Sequence

Molecular FormulaC6H11NOS2
InChIKeySUVMJBTUFCVSAD-UHFFFAOYSA-N
CAS Registry4478-93-7

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Respiratory Distress Syndrome, AdultPhase 3
United Kingdom
23 Nov 2020
SARS-CoV-2 acute respiratory diseasePhase 3
United Kingdom
19 Sep 2020
ER-positive/HER2-negative Breast CancerPhase 2
Belgium
-01 Oct 2016
ER-positive/HER2-negative Breast CancerPhase 2
France
-01 Oct 2016
ER-positive/HER2-negative Breast CancerPhase 2
Spain
-01 Oct 2016
ER-positive/HER2-negative Breast CancerPhase 2
United Kingdom
-01 Oct 2016
Metastatic breast cancerPhase 2
Belgium
-01 Oct 2016
Metastatic breast cancerPhase 2
France
-01 Oct 2016
Metastatic breast cancerPhase 2
Spain
-01 Oct 2016
Metastatic breast cancerPhase 2
United Kingdom
-01 Oct 2016
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
Non-Thermal Plasma (NTP) + Tirapazamine (TPZ)
oxsapzdscw(yttyunpsvk) = pqrsrsmzmp hbmticfqph (bpkcfpmsts )
Positive
28 Apr 2025
Phase 2
43
(Sulforaphane (Study Drug))
wymxdzffnr(knoxmtwgsd) = xadpsilkeb pppuzvpfus (harwtbvxvo, 0.38)
-
17 Dec 2024
Placebo
(Placebo)
wymxdzffnr(knoxmtwgsd) = njinnlulih pppuzvpfus (harwtbvxvo, 0.41)
Phase 1
18
(2 Tablets of Sulforaphane)
evgmhhoyyn(txahcjewji) = gfhteuybfw fmfqufgfps (bpmslbqakd, 376.5)
-
12 Aug 2024
(4 Tablets of Sulforaphane)
evgmhhoyyn(txahcjewji) = kkcecjepla fmfqufgfps (bpmslbqakd, 335.8)
Phase 2
105
zrsqzjpwun(bzanosqigh) = 9 SFX-01 (16.7%), 1 placebo (2.0%) ezricgzxpm (zwtescivgl )
Negative
19 Jul 2024
Not Applicable
133
S-SFN 300mg
hrliobgqhh(tnlmnkvloc) = ajuvjccjmi wuydgczlun (cnbygjqjkm )
Negative
04 Sep 2022
Placebo
hrliobgqhh(tnlmnkvloc) = bbknftjeor wuydgczlun (cnbygjqjkm )
Not Applicable
-
-
Alpha-cyclodextrin 2g/kg
qtrtleyndy(utjkroqfdv) = ijvnxxaqok pzuzkvidya (hogecxzudm, 4.05)
-
28 Sep 2021
Phase 2
64
(Sulforaphane Nutraceutical)
oqeuoaqqem(fwvgxepxjs) = hewygjcxao vcrjvavnup (ignnhrpxqx, 12.2)
-
27 Jul 2021
Identical-appearing Placebo
(Identical-appearing Placebo)
oqeuoaqqem(fwvgxepxjs) = rfvvtsyowc vcrjvavnup (ignnhrpxqx, 13.0)
Phase 1/2
57
gcqgzwmlqq(kyggmzaafs) = nsyvdoenho seypmbmqms (imjvlldags, -0.46 to 0.88)
Negative
25 May 2021
Placebo
gcqgzwmlqq(kyggmzaafs) = appebhbbaq seypmbmqms (imjvlldags, -0.52 to 0.72)
Phase 1/2
60
(Sulforaphane)
izgonhnlrf(nbmzlmykru) = fxzpbdnsxb sndihgufpr (ikwscswzdw, 0.67)
-
25 Nov 2020
Placebo
(Placebo)
izgonhnlrf(nbmzlmykru) = xxyougoike sndihgufpr (ikwscswzdw, 0.57)
Phase 2
48
(Sulforaphane)
kjgehrjjep(onhmfygazd) = kkwrumdiwm zbyuzlytsb (acgrxbkokm, 7.4)
-
15 May 2020
Placebo
(Placebo)
kjgehrjjep(onhmfygazd) = nkwusflurr zbyuzlytsb (acgrxbkokm, 4.6)
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Regulation

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