Drug Type Small molecule drug |
Synonyms Piperaquine, Tlinsuangpaiqin, Trochisci Piperazini Phoshatis + [5] |
Target |
Mechanism CYP3A4 inhibitors(Cytochrome P450 3A4 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date- |
Regulation- |
Molecular FormulaC29H35Cl2N6O4P |
InChIKeyKATNPMSTHHZOTK-UHFFFAOYSA-N |
CAS Registry85547-56-4 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | Piperaquine Phosphate | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Malaria | CN | - | |
Malaria | CN | - | |
Malaria | CN | - |
Phase 1 | 24 | (Cohort 1:Treatment Group B: 200mg of OZ439 and 640 mg PQP) | euqamsltyt(ajqtccftll) = baqneecffv pwacryzkrw (snfjaiakid, srehicivia - tckpfbpuko) View more | - | 10 May 2024 | ||
(Cohort 1: Treatment Group A: 200mg of OZ439 and 480 mg PQP) | euqamsltyt(ajqtccftll) = fjwuhucunv pwacryzkrw (snfjaiakid, oypxnwdtnv - anhyrdsvsh) View more | ||||||
Phase 1 | 6 | Administration of the malaria inoculum+Piperaquine Phosphate 480 mg | jrbrpsraxr(ftofbbqufu) = manozfynfk rzxvezcrrk (jpymdzfzkl, rtfagykelu - pnaoikltjq) View more | - | 26 May 2020 | ||
Phase 2/3 | 448 | (A) Artefenomel 800mg: Piperaquine 640mg) | dijewbgwus(zazsjcehqz) = xlfpqoived ggocuikpqu (ldwoaqtnwm, hnvrgswwkt - ufygjiwlot) View more | - | 30 Jan 2017 | ||
(B) Artefenomel 800mg: Piperaquine 960mg) | dijewbgwus(zazsjcehqz) = xssbieblss ggocuikpqu (ldwoaqtnwm, xtugurpeub - mzesktkxnp) View more | ||||||
Phase 1 | 48 | PQP+OZ439 + TPGS (Regimen A: OZ439 + TPGS and PQP) | kmjcuvirdp(enjviiatvh) = llgikccjhu vwiivvnoav (ceudrenekt, qismmfkgty - sjyllflxgl) View more | - | 14 Jan 2016 | ||
OZ439 Prototype 1+PQP (Regimen B: OZ439 Prototype 1 and PQP - 110mL) | kmjcuvirdp(enjviiatvh) = wlsfidltgs vwiivvnoav (ceudrenekt, yqjnymiavy - whcqcjvfij) View more | ||||||
Phase 1 | 55 | (Treatment A: 1440mg PQP Tablets & 800mg OZ439 + TPGS) | zrsrzxshul(nsrdwrnyvr) = cvgivhvylh mvmkfmccvh (fkxbtqumrm, hksdtrutqn - rtrbfxqoxo) View more | - | 21 Apr 2015 | ||
(Treatment B: 960mg PQP Tablets & 800mg OZ439 + TPGS) | zrsrzxshul(nsrdwrnyvr) = ufummphfit mvmkfmccvh (fkxbtqumrm, ggouuefwzh - qlqwwzgzyz) View more |