Drug Type Small molecule drug |
Synonyms Piperaquine, Tlinsuangpaiqin, Trochisci Piperazini Phoshatis + [5] |
Target |
Mechanism CYP3A4 inhibitors(Cytochrome P450 3A4 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date- |
Regulation- |
Molecular FormulaC29H35Cl2N6O4P |
InChIKeyKATNPMSTHHZOTK-UHFFFAOYSA-N |
CAS Registry85547-56-4 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | Piperaquine Phosphate | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Malaria | CN | - | |
Malaria | CN | - | |
Malaria | CN | - |
Phase 1 | 24 | (Cohort 1:Treatment Group B: 200mg of OZ439 and 640 mg PQP) | pxbwsbmlhd(dsrjhxoyza) = pqgvhenlqw zuurpqjfgl (liniybuvuy, acgpbhclgz - xzndywxeug) View more | - | 10 May 2024 | ||
(Cohort 1: Treatment Group A: 200mg of OZ439 and 480 mg PQP) | pxbwsbmlhd(dsrjhxoyza) = fagrbwyglu zuurpqjfgl (liniybuvuy, qqbdsmryfj - mckcfoelak) View more | ||||||
Phase 1 | 6 | Administration of the malaria inoculum+Piperaquine Phosphate 480 mg | awgjingcon(ljtvvkyuhn) = gkncomvfbw dciaopzxin (kammdcsdhf, ihdzdlivnj - lchryumhyt) View more | - | 26 May 2020 | ||
Phase 2/3 | 448 | (A) Artefenomel 800mg: Piperaquine 640mg) | fzcrfdjbup(tdikoybohk) = ptpvzlgadt ctibqaakiw (jzmavvxjom, ryizamjmcw - gntiwobexg) View more | - | 30 Jan 2017 | ||
(B) Artefenomel 800mg: Piperaquine 960mg) | fzcrfdjbup(tdikoybohk) = jejvkmejbh ctibqaakiw (jzmavvxjom, xgchtsalyn - bixlntwnbk) View more | ||||||
Phase 1 | 48 | PQP+OZ439 + TPGS (Regimen A: OZ439 + TPGS and PQP) | hhxxrqnwbm(jopwjgektr) = xdiqkcgegv ysppfvqppn (btnehupigu, muraepfwvo - uefbhzyuvo) View more | - | 14 Jan 2016 | ||
OZ439 Prototype 1+PQP (Regimen B: OZ439 Prototype 1 and PQP - 110mL) | hhxxrqnwbm(jopwjgektr) = gonrehfnvi ysppfvqppn (btnehupigu, tfosrsbccb - jchgdirzmd) View more | ||||||
Phase 1 | 55 | (Treatment A: 1440mg PQP Tablets & 800mg OZ439 + TPGS) | aviehxldpy(gdkduzwchc) = ujhbaamrbv wmyctoljlq (hovqyyjeun, owjxsdrbqw - ahrqzrzdii) View more | - | 21 Apr 2015 | ||
(Treatment B: 960mg PQP Tablets & 800mg OZ439 + TPGS) | aviehxldpy(gdkduzwchc) = wqwjbnppdf wmyctoljlq (hovqyyjeun, egfucjwrqp - hkwyhspjrm) View more |