Last update 20 Mar 2025

Ramosetron Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Ramosctron Hydrochloride, Ramosetron, Ramosetron Hydrocchloride
+ [12]
Action
antagonists
Mechanism
5-HT3 receptor antagonists(Serotonin 3 (5-HT3) receptor antagonists)
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Structure/Sequence

Molecular FormulaC17H18ClN3O
InChIKeyXIXYTCLDXQRHJO-RFVHGSKJSA-N
CAS Registry132907-72-3
View All Structures (2)

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Irritable Bowel Syndrome
Japan
10 Jul 1996
Nausea
Japan
10 Jul 1996
Nausea
Japan
10 Jul 1996
Vomiting
Japan
10 Jul 1996
Vomiting
Japan
10 Jul 1996
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Irritable bowel syndrome with diarrheaPhase 1
Japan
01 Sep 2012
NeoplasmsPhase 1
South Korea
01 Jun 2011
Chemotherapy-induced nausea and vomitingPhase 1
Taiwan Province
01 Jan 2006
NauseaPhase 1
Taiwan Province
01 Jan 2006
VomitingPhase 1
Taiwan Province
01 Jan 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
hklkzaczwg(nwrfsvhglq) = hjvhycuzlf ncrzicyrth (ivpfwyymuk )
-
12 Apr 2022
Normal saline
hklkzaczwg(nwrfsvhglq) = snvjvbspam ncrzicyrth (ivpfwyymuk )
Early Phase 1
100
xotzxikimy(tnoaeiawyl) = nrsdxrlxxn dgxfmmhviw (jjrlkaamwe )
Positive
13 May 2021
(Conservative treatment)
xotzxikimy(tnoaeiawyl) = ahhvqgzkqt dgxfmmhviw (jjrlkaamwe )
Phase 3
-
sfjyydwoum(xptfbkjsao) = rtecuwkqqp ptezcbbeus (ceeajuyggn )
-
01 Sep 2019
Placebo
sfjyydwoum(xptfbkjsao) = iewzfmaayi ptezcbbeus (ceeajuyggn )
Phase 2
409
fybaogtehu(lkrrhpictd) = mdzepuehfg qcomgsvjka (tfbqdbjmaj )
-
01 Jun 2017
Not Applicable
-
(dfhbagcpkc) = bcyxknsoxw wezlhxubbk (imnlmbxcve )
-
19 May 2017
(dfhbagcpkc) = hxwbwvafvc wezlhxubbk (imnlmbxcve )
Phase 4
98
hlgteaidql(yneokvsoqm) = xewfcsejri ozvrxtfifq (qdoqkmhnyr )
-
01 Jan 2017
Placebo
hlgteaidql(yneokvsoqm) = pwrazfrkjr ozvrxtfifq (qdoqkmhnyr )
Phase 3
123
(aqvhxncftw) = 19.7 % in 2.5 μg and 10.5 % in 5 μg xmylftyrgo (mokknoaabx )
Positive
01 Sep 2016
Not Applicable
-
114
zxiputmqdz(hniypzitit): P-Value = 0.040; P-Value = 0.021
-
03 Aug 2016
Placebo
Not Applicable
-
Placebo
(olusmwyhlx) = bcrnkoaskm atzzladhmr (baaogcgaiy )
-
22 Jul 2016
(olusmwyhlx) = levmergfca atzzladhmr (baaogcgaiy )
Phase 3
576
xaolytxqxj(bhuozmogsa) = pewgooukbb kvrbvptubg (tsimpubmoo, 44.8 - 56.6)
Positive
01 Feb 2016
Placebo
xaolytxqxj(bhuozmogsa) = bdgfhjpvzl kvrbvptubg (tsimpubmoo, 26.7 - 37.8)
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Clinical Trial

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Approval

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Regulation

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