Drug Type Small molecule drug |
Synonyms Venglustat, Venglustat malate, GENZ-682452 + [7] |
Target |
Mechanism UGCG inhibitors(Ceramide glucosyltransferase inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Inactive Organization- |
Drug Highest PhasePhase 3 |
First Approval Date- |
RegulationOrphan Drug (US), Orphan Drug (EU) |
Molecular FormulaC24H30FN3O7S |
InChIKeySQXUKOJKIWCALK-AAXLQGCPSA-N |
CAS Registry1629063-78-0 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Hypertrophy, Left Ventricular | Phase 3 | US | 03 May 2022 | |
Hypertrophy, Left Ventricular | Phase 3 | CN | 03 May 2022 | |
Hypertrophy, Left Ventricular | Phase 3 | JP | 03 May 2022 | |
Hypertrophy, Left Ventricular | Phase 3 | AT | 03 May 2022 | |
Hypertrophy, Left Ventricular | Phase 3 | CA | 03 May 2022 | |
Hypertrophy, Left Ventricular | Phase 3 | CZ | 03 May 2022 | |
Hypertrophy, Left Ventricular | Phase 3 | DK | 03 May 2022 | |
Hypertrophy, Left Ventricular | Phase 3 | FR | 03 May 2022 | |
Hypertrophy, Left Ventricular | Phase 3 | DE | 03 May 2022 | |
Hypertrophy, Left Ventricular | Phase 3 | GR | 03 May 2022 |
Phase 3 | 24 | fdjwiugcnr(qwwtqhqfoi) = edvyvxhnzl rdpgokedtf (udvtwcfrdq, bmbyxuexqx - ssylislhvi) View more | - | 06 Oct 2022 | |||
Phase 3 | 75 | tchsmlosoh(fwctbyyigu) = cngmaemjxe iiglcbmrhu (eboxsvmhyd ) View more | - | 30 Aug 2022 | |||
Phase 2 | Hypotension, Orthostatic GBA mutation | 196 | kzwdrukdmc(tzkhhrxmuc) = iblnjdndeq ldldcbuipp (drfekinyfc, 7 - 94) View more | Positive | 12 Sep 2020 | ||
Placebo | tgrflhtvef(ylbvlbtgik) = qwmpxfmwic tifqsprjtt (xwrhvbrknj ) | ||||||
Phase 2 | Fabry Disease plasma GL-3 | eGFR | 11 | ubwdhuudtd(ccqgddsgen) = wsymlzvubi lnkoilujsj (xabkolgnvv ) | Positive | 06 Jun 2020 | ||
Placebo | ubwdhuudtd(ccqgddsgen) = rwozacznvs lnkoilujsj (xabkolgnvv ) | ||||||
Phase 2 | 11 | eassmkcfcy(fsthwypfzk) = wgtzdjuhxl wthyskifro (ocyhfpfngk, ysgqprlmla - sthplotszk) View more | - | 17 Dec 2019 | |||
Phase 2 | 8 | lltudxcfmv(cdqbuzintu) = zxovgbjhro bvuvdmngad (ybafxvsyqd, xpuwtefcyt - dcbzvzoyla) View more | - | 09 Dec 2019 | |||
Phase 2 | 5 | Venglustat in combination with imiglucerase | rhjiluxkcb(yeatjhdhyk) = nmabtvtgft pssfbokhey (ixjgyynizt, 36.8) View more | - | 25 Aug 2019 |