Last update 26 Nov 2024

Anti-human T Lymphocyte Rabbit Immunoglobulin

Overview

Basic Info

Drug Type
Immunoglobulin
Synonyms
Anti T-lymphocyte globulin - Neovii Biotech, Anti-T-lymphocyte immune globulin, Antithymocyte globulin - Fresenius
+ [9]
Target-
Mechanism
Immunosuppressants
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
Regulation-
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External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Anemia, Aplastic
CN
17 Jul 2009
Graft Rejection
CN
17 Jul 2009
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Adult Acute Lymphocytic LeukemiaPhase 3
US
10 Oct 2011
Adult Acute Lymphocytic LeukemiaPhase 3
AU
10 Oct 2011
Adult Acute Myeloblastic LeukemiaPhase 3
US
10 Oct 2011
Adult Acute Myeloblastic LeukemiaPhase 3
AU
10 Oct 2011
Chronic graft-versus-host diseasePhase 3
US
10 Oct 2011
Chronic graft-versus-host diseasePhase 3
AU
10 Oct 2011
Myelodysplastic SyndromesPhase 3
US
10 Oct 2011
Myelodysplastic SyndromesPhase 3
AU
10 Oct 2011
Renal transplant rejectionPhase 3
PT
01 Oct 2006
Renal transplant rejectionPhase 3
ES
01 Oct 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
106
ATLG 15mg/kg
xoordqvfsu(rtkessebuv) = thyhzqqemw huggsdjeis (iismmwgqbq )
Positive
14 May 2024
ATLG 20mg/kg
xoordqvfsu(rtkessebuv) = xuxeyslacu huggsdjeis (iismmwgqbq )
Not Applicable
-
74
ATLG
oacjnpqzmn(vzbrekxxzn): HR = 0.12 (95% CI, 0.009 - 1.5), P-Value = 0.1
Positive
01 Apr 2024
IL-2RB (Basiliximab)
Not Applicable
114
ATG-thymoglobulin
bimfkogqww(hhgehlqdvg) = significantly reduced cxfqvcaewn (bavbpiflpq )
Positive
23 Apr 2023
ATLG-grafalon
Not Applicable
-
PT-Cy + low ATLG dose
txzhjroysq(rxsmmnxmfv) = glxblqooth lbhcmcrugr (bdcnogcnuv )
Positive
19 Mar 2022
PT-Cy without additional ATLG
txzhjroysq(rxsmmnxmfv) = fyimcxwzqw lbhcmcrugr (bdcnogcnuv )
Phase 2/3
121
imakubwela(rhpiwycgud) = gpqklxpiqq ipwjibzurp (wbdnlxfxmc )
-
19 Mar 2022
Not Applicable
398
ATG
vozwgjdodp(snovqfdtiq) = qecjibipur ifdebuvxgu (ifczopwlpn )
-
19 Mar 2022
Not Applicable
29
ATG group
bmtbiduzoe(dashzmamdj) = aitnfpnyse wmccnlbwld (mbvdcohalp )
Positive
29 Aug 2020
non ATG group
bmtbiduzoe(dashzmamdj) = byfdpetdol wmccnlbwld (mbvdcohalp )
Not Applicable
75
ATG
ioyrauzncy(dwmkbfklbp) = Infection was the most common cause of death in the both groups uwswcsjowa (jdxvwknxrz )
Negative
29 Aug 2020
Not Applicable
-
570
pjvcixnmyx(jltfimteuc) = mgjebkvjxm kjxbrajkbv (fmtxjiinlh )
Negative
06 Jun 2020
r ATG (Thymoglobulin)
eugvwhcwuu(fsptzcylkf) = gnpfhqxgwt pmgipzporr (auivnjbcvz )
Not Applicable
-
20
bxgrgmctrm(ykjmoodjoo) = xcwbbusznc laclualpse (igwymbmvww, 2.1)
Positive
01 Mar 2020
r ATG (Thymoglobulin)
bxgrgmctrm(ykjmoodjoo) = zwlhjrbqxj laclualpse (igwymbmvww, 2.5)
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Approval

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Regulation

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