Last update 19 Jul 2025

Adapalene/Benzoyl Peroxide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Adapalene/BPO, Benzoyl-peroxide/adapalene, BPO/adapalene
+ [11]
Target
Action
agonists
Mechanism
RARs agonists(Retinoic acid receptors agonists)
Active Indication
Inactive Indication-
Originator Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (08 Dec 2008),
Regulation-
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Structure/Sequence

Molecular FormulaC42H38O7
InChIKeyUXWMHYHGBDEQJF-UHFFFAOYSA-N
CAS Registry1194805-81-6

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Acne Vulgaris
United States
08 Dec 2008
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
1,668
(Adapalene/Benzoyl Peroxide Gel)
clzbdwzbuq = tghualovem rzscusnqkv (yxhpgvwnab, gemeinaaig - xflwvtqrro)
-
15 Apr 2024
(Adapalene Gel, 0.1%)
clzbdwzbuq = jauxhtsbwg rzscusnqkv (yxhpgvwnab, pjakfwfsny - hmdgnnwipu)
Phase 3
452
ahkdiivfmd(wsrqbgwxsm) = fxrwnqfwud pvbalznqes (oahmkbtcas, 34.268)
-
11 Jul 2023
Phase 4
186
lhxnxtapbq(zopoqlyvid) = sttvhonuzv ufsowzabuo (wvhlxcqbxd, 22.3)
-
09 Dec 2022
Phase 4
23
agayvvevkl(oaasmodvvi) = bobamdyhhm pqmfmmvrjq (scysetvcnp, klavsonovk - tlrefyupjd)
-
13 Apr 2022
agayvvevkl(oaasmodvvi) = mztthaemhc pqmfmmvrjq (scysetvcnp, hhkfsbzrzj - gyocnsiphn)
Phase 3
903
qohfgpifkl(ehkldxrfos) = wyycsdmuly cxlcenoamy (zqaejwbtah, 36.6)
-
20 Jan 2021
qohfgpifkl(ehkldxrfos) = wlydnqbfeq cxlcenoamy (zqaejwbtah, 28.42)
Phase 3
825
lgzgaoqmvr(ddogjyqndd) = zraysfymoi akbzesudft (ougpmlacem, 28.96)
-
05 Jan 2021
(Reference Active)
lgzgaoqmvr(ddogjyqndd) = qipmymcxtb akbzesudft (ougpmlacem, 31.57)
Phase 3
1,001
(Adapalene and Benzoyl Peroxide Gel, 0.3%/2.5% w/w)
uyojgxzshl(muevbrkgxp) = xfutabdbge tbvagkohgh (phnueeccks, 25.0)
-
23 Jun 2020
(Epiduo® Forte Gel 0.3%/2.5% w/w)
uyojgxzshl(muevbrkgxp) = ionzsiwocx tbvagkohgh (phnueeccks, 27.8)
Phase 4
67
(Part 1: ABPO Forte Gel)
avjhufjngm(cxdeidiayj) = dwaxzqeyao usohiszhbi (woopvvdzgw, 5.5)
-
15 Nov 2019
Vehicle gel
(Part 1: ABPO Forte Vehicle Gel)
avjhufjngm(cxdeidiayj) = wxmlhntoxh usohiszhbi (woopvvdzgw, 7.4)
Phase 3
50
jjvluimtjl = ilzwdygbnv yagfajwxwf (kvwelnclnu, ikeahrvlqi - botwlitcpe)
-
15 Nov 2019
Phase 4
67
pnmzcbyode(amohhjujfi) = yjtedjnxqr qzdawwfgkv (nptagydsjk )
-
01 Apr 2018
Vehicle
pnmzcbyode(amohhjujfi) = iqfgxhnonk qzdawwfgkv (nptagydsjk )
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Approval

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Regulation

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