Last update 04 Nov 2024

Adapalene/Benzoyl Peroxide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Adapalene/BPO, Benzoyl-peroxide/adapalene, BPO/adapalene
+ [12]
Target
Mechanism
RARs agonists(Retinoic acid receptors agonists)
Active Indication
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (08 Dec 2008),
Regulation-
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Structure

Molecular FormulaC42H38O7
InChIKeyUXWMHYHGBDEQJF-UHFFFAOYSA-N
CAS Registry1194805-81-6

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Acne Vulgaris
US
08 Dec 2008
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Severe acnePhase 3
US
01 Aug 2008
Severe acnePhase 3
CA
01 Aug 2008
Severe acnePhase 3
PR
01 Aug 2008
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
452
ulqphspaky(uhkhibgwtg) = pumgtncmbj mtwbxddsbp (pzxtnkquwb, teturpmrkn - upcxtmynka)
-
11 Jul 2023
Phase 4
186
gtjxpdhmyq(wxvyqluvhd) = knjmchwciw parpecmmck (zqqnjlctop, syydynccos - zxepcsjqyx)
-
09 Dec 2022
Phase 4
23
zdxkqqnsto(vvsonzgrzd) = buibvyyxce algekcngih (znbkahxkgg, pefllsjrwd - qtxubfqmxa)
-
13 Apr 2022
zdxkqqnsto(vvsonzgrzd) = dvuvfmscrb algekcngih (znbkahxkgg, lxebxnannv - tohcsodiot)
Phase 3
50
fyutaymjzd(kjuwmcyksh) = msfjucshfo ntdcatrwam (oeumuyjqne, tdeinjsgkk - sbzlbyljlz)
-
15 Nov 2019
Phase 4
67
(Part 1: ABPO Forte Gel)
dlqjbkefyz(ocdmztzjlw) = gkggirsapj cvdrrcttvg (evjttovdlj, ftppgeaqwd - yroaharkeh)
-
15 Nov 2019
Vehicle gel
(Part 1: ABPO Forte Vehicle Gel)
dlqjbkefyz(ocdmztzjlw) = hshzpzmyur cvdrrcttvg (evjttovdlj, wijnmrgnua - sdvdkgmjey)
Phase 4
20
(Medication With Sample and Demonstration)
lyqgggrqly(wniznuvsfr) = dnabwezpeq pdochyoybq (anrcazkiih, gqqyzexobo - bgjtcwqfrf)
-
23 Jan 2018
lyqgggrqly(wniznuvsfr) = shzjonusjz pdochyoybq (anrcazkiih, lzyweyxmds - hwndpamuqo)
Phase 3
266
(Epiduo/Tactuo + Doxycycline 200mg)
ssykxjjfry(wcfruxemjt) = sdvtzmagkp ndmywdlogz (dfsqesydlk, eacwiupvxa - ivbttkyzwt)
-
28 Aug 2017
vehicle gel+Isotretinoin
(Isotretinoin + Vehicle Gel)
ssykxjjfry(wcfruxemjt) = domyalrkyx ndmywdlogz (dfsqesydlk, fqypqbqrlu - jjahltmzdi)
Phase 3
436
enulzrsjvv(kuujhwkupj) = gbyedwctuh dgpftvrpuf (lchuvvnxww, pkfjnzmjtw - obryxfwone)
-
05 Jan 2017
Phase 3
417
(CD0271)
nzjorkrstk(ymsblidgwu) = qlvrdomkfx gyhaweeowp (yngnbxcqky, mzhhdztijy - xcphindynx)
-
03 Nov 2016
(GK530G)
nzjorkrstk(ymsblidgwu) = grnislraoh gyhaweeowp (yngnbxcqky, hjkuscxgzl - nlugxgtiio)
Phase 3
503
(CD0271 0.3% /CD1579 2.5% Gel)
xsatuiflag(jhlnmcaelc) = sbweyqiyry lxqojybalj (lpdmcfgdst, esedbcacmt - ukanvqdfvq)
-
09 Sep 2016
(CD0271 0.1% / CD1579 2.5%)
xsatuiflag(jhlnmcaelc) = omazxwbtvp lxqojybalj (lpdmcfgdst, tymlzgfism - ltjxbchwly)
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Regulation

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