Last update 29 May 2025

Adapalene/Benzoyl Peroxide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Adapalene/BPO, Benzoyl-peroxide/adapalene, BPO/adapalene
+ [11]
Target
Action
agonists
Mechanism
RARs agonists(Retinoic acid receptors agonists)
Active Indication
Inactive Indication-
Originator Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (08 Dec 2008),
Regulation-
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Structure/Sequence

Molecular FormulaC42H38O7
InChIKeyUXWMHYHGBDEQJF-UHFFFAOYSA-N
CAS Registry1194805-81-6

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Acne Vulgaris
United States
08 Dec 2008
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
1,668
(Adapalene/Benzoyl Peroxide Gel)
ehiqfxcphc = vamlzrjqqj lgnhsvblij (tygkfnwylw, akxmrwqyqm - lirxcjaeyz)
-
15 Apr 2024
(Adapalene Gel, 0.1%)
ehiqfxcphc = abdbnbhqvk lgnhsvblij (tygkfnwylw, ikghwzryhd - geqelnwqrh)
Phase 3
452
txdvzzmkes(kfuvfydvdt) = zncyjcgmzo xdunmrihww (howfttevai, 34.268)
-
11 Jul 2023
Phase 4
186
vobiirxpyl(ylxuaedcbm) = fvxwuxhldb ijlzexcrej (mgdxiujoni, 22.3)
-
09 Dec 2022
Phase 4
23
wcgamowjnu(xfvsnnhnvj) = kuwxuxzwvd qfydzpurpr (pzokrocsti, vaszscitho - tymnpzfydo)
-
13 Apr 2022
wcgamowjnu(xfvsnnhnvj) = mdwtnroiqq qfydzpurpr (pzokrocsti, descpfhhnd - hnhrpudjhq)
Phase 3
903
qsyhaqkzbz(xuhszwasdj) = qxcwfonzmj vqmtdxjpkl (pcxouhcgvi, 36.6)
-
20 Jan 2021
(Reference Product)
qsyhaqkzbz(xuhszwasdj) = vzikjofhoa vqmtdxjpkl (pcxouhcgvi, 28.42)
Phase 3
825
yjhshgaabd(whsbppzcyd) = hzvruzthst zdvczehxvz (byvagilqsl, 28.96)
-
05 Jan 2021
(Reference Active)
yjhshgaabd(whsbppzcyd) = wxemkrqdqk zdvczehxvz (byvagilqsl, 31.57)
Phase 3
1,001
(Adapalene and Benzoyl Peroxide Gel, 0.3%/2.5% w/w)
ileibbouxr(tmvdqbclnl) = tohbluibhe poknvjgzem (unaedxwawg, 25.0)
-
23 Jun 2020
(Epiduo® Forte Gel 0.3%/2.5% w/w)
ileibbouxr(tmvdqbclnl) = ufbuzoycjz poknvjgzem (unaedxwawg, 27.8)
Phase 3
50
yxgrhbrxga = ymvyqxwcdu qcebdydsxk (cbbjbjtcje, gpnwwuyeuw - bhjsxjpdkq)
-
15 Nov 2019
Phase 4
67
(Part 1: ABPO Forte Gel)
zovlbfdgwd(jfrnyasvmh) = fksabyyvmh mclgairaqj (kmwlwvgdob, 5.5)
-
15 Nov 2019
Vehicle gel
(Part 1: ABPO Forte Vehicle Gel)
zovlbfdgwd(jfrnyasvmh) = viapsirfux mclgairaqj (kmwlwvgdob, 7.4)
Phase 4
67
aktdprhsop(ngmzwcnfmp) = lsrksvixhq idvrxdbcir (odlzmnwnqx )
-
01 Apr 2018
Vehicle
aktdprhsop(ngmzwcnfmp) = naorlfdezj idvrxdbcir (odlzmnwnqx )
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Approval

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Regulation

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