Last update 21 Nov 2024

Obicetrapib/Ezetimibe

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
CETP x NPC1L1
Mechanism
CETP inhibitors(Cholesteryl ester transfer protein inhibitors), NPC1L1 inhibitors(Niemann-Pick C1-like protein 1 inhibitors)
Therapeutic Areas
Cardiovascular Diseases
Active Indication
Plaque, Atherosclerotic
Inactive Indication-
Originator Organization
NewAmsterdam Pharma Co. NV
Active Organization
NewAmsterdam Pharma Holding BVNewAmsterdam Pharma Holding BV
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
Regulation-
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Structure

Molecular FormulaC32H31F9N4O5
InChIKeyNRWORBQAOQVYBJ-GJZUVCINSA-N
CAS Registry866399-87-3
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Related

1
Clinical Trials associated with Obicetrapib/Ezetimibe
NCT06005597 / CompletedPhase 3
A Placebo-Controlled, Double-Blind, Randomized, Phase 3 Study to Evaluate the Effect of Obicetrapib 10 mg and Ezetimibe 10 mg Fixed Dose Combination Daily on Top of Maximally Tolerated Lipid-Modifying Therapy in Participants With Heterozygous Familial Hypercholesterolemia (HeFH) and/or Atherosclerotic Cardiovascular Disease (ASCVD) or Multiple ASCVD Risk Factors
100 Clinical Results associated with Obicetrapib/Ezetimibe
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100 Translational Medicine associated with Obicetrapib/Ezetimibe
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100 Patents (Medical) associated with Obicetrapib/Ezetimibe
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100 Deals associated with Obicetrapib/Ezetimibe
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Plaque, AtheroscleroticPhase 3
US
NewAmsterdam Pharma Holding BVNewAmsterdam Pharma Holding BV
16 May 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Approval

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Regulation

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