Last update 25 Jul 2025

Ifupinostat

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
双利司他, 双替尼他, BEBT-908
+ [4]
Action
inhibitors
Mechanism
HDAC inhibitors(Histone deacetylase inhibitors), PI3K family inhibitors(Phosphatidylinositol 3-kinase family inhibitors), Epigenetic drug
Originator Organization
Active Organization
Inactive Organization-
License Organization
Drug Highest PhaseApproved
RegulationBreakthrough Therapy (China), Conditional marketing approval (China), Priority Review (China)
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Structure/Sequence

Molecular FormulaC23H28Cl3N9O3S
InChIKeyXQJBSJNJWWXTFM-UHFFFAOYSA-N
CAS Registry1646906-27-5

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Diffuse large B-cell lymphoma recurrent
China
30 Jun 2025
Diffuse large B-cell lymphoma refractory
China
30 Jun 2025
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Lung Non-Small Cell CarcinomaPhase 2
China
28 Mar 2022
Hormone receptor positive HER2 negative breast cancerPhase 2
China
23 Feb 2022
Peripheral T-Cell LymphomaPhase 2
China
16 Aug 2021
Chronic Lymphocytic LeukemiaPhase 2
China
12 Aug 2021
Follicular LymphomaPhase 2
China
12 Aug 2021
Marginal Zone B-Cell LymphomaPhase 2
China
12 Aug 2021
Small Lymphocytic LymphomaPhase 2
China
12 Aug 2021
Waldenstrom MacroglobulinemiaPhase 2
China
12 Aug 2021
Advanced Malignant Solid NeoplasmPhase 2
China
-
Recurrent LymphomaPhase 1
China
14 Mar 2016
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
Diffuse Large B-Cell Lymphoma
Second line
anti-CD20 antibody
24
ttsuivkvqn(qfscjgslrq) = ndqlpboypv dabozqebrf (klezcdwvdp )
Positive
30 May 2025
Phase 2
-
ztndzcmjkf(qwrvimpank) = lvzhyvaaoo mgwqktpxps (zajbvrbnps )
Positive
20 Jul 2023
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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