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Last update 21 Oct 2026
Nelmastobart
Last update 21 Oct 2026
Overview
Basic Info
Drug Type Monoclonal antibody |
Synonyms Anti STT-003 Ab, Anti-butyrophilin 1A1 mAb(STCube/MD Anderson Cancer Center), 人源化抗BTN1A1单克隆抗体（ST立方公司） + [3] |
Target |
Action inhibitors |
Mechanism BTN1A1 inhibitors(butyrophilin subfamily 1 member A1 inhibitors) |
Therapeutic Areas |
Inactive Indication |
Originator Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
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Structure/Sequence
Sequence Code 776944511H
Source: *****
Sequence Code 776944512L
Source: *****
Related
5
Clinical Trials associated with NelmastobartNCT07656038
A Single-arm, Open-label, Phase Ib Clinical Trial Evaluating the Safety, Pharmacokinetics, Immunogenicity, and Preliminary Efficacy of Nelmastobart in Combination With TAS-102 and Bevacizumab in Recurrent/Metastatic Colorectal Cancer
NCT07306624
A Multicenter, Phase 2 Clinical Trial Based on an Adaptive Design to Evaluate the Safety and Efficacy of Nelmastobart in Combination With Docetaxel in Patients With Advanced/Metastatic Non-Small Cell Lung Cancer Who Are Resistant or Intolerant to Platinum-based Chemotherapy and/or Immunotherapy
NCT06873763
A Single-arm, Phase Ib/2 Study of Nelmastobart in Combination With Trifluridine/Tipiracil and Bevacizumab in Metastatic/Recurrent Colorectal Cancer Patients With Resistance or Intolerance to Oxaliplatin and Irinotecan-based Chemotherapy
100 Clinical Results associated with Nelmastobart
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100 Translational Medicine associated with Nelmastobart
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100 Patents (Medical) associated with Nelmastobart
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100 Deals associated with Nelmastobart
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External Link
| KEGG | Wiki | ATC | Drug Bank |
|---|---|---|---|
| D13065 | - | - | - |
R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Recurrent Non-Small Cell Lung Cancer | Phase 2 | South Korea | 10 Jan 2026 | |
| Metastatic Colorectal Carcinoma | Phase 2 | South Korea | 09 Jun 2025 | |
| Extensive stage Small Cell Lung Cancer | Phase 2 | United States | 13 Feb 2024 | |
| Extensive stage Small Cell Lung Cancer | Phase 2 | South Korea | 13 Feb 2024 | |
| Head and Neck Neoplasms | Phase 2 | South Korea | - | |
| Head and Neck Neoplasms | Phase 2 | - | - | |
| Colorectal Cancer | Phase 1 | China | 03 Jun 2026 | |
| Advanced Malignant Solid Neoplasm | Phase 1 | United States | 18 Apr 2022 | |
| Advanced Malignant Solid Neoplasm | Phase 1 | South Korea | 18 Apr 2022 | |
| Colorectal cancer recurrent | IND Approval | China | 07 Mar 2026 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
Phase 1/2 | Colorectal Cancer BTN1A1 | 6 | vgrodigdgk(wcjbiacpxu) = ydaeajfotw wdtbbbnzsm (jukkhyyott ) View more | Positive | 08 Jan 2026 | ||
Phase 1 | Colonic Cancer BTN1A1 | YAP1 | - | ywjlkwivaf(eotebznifc) = Treatment with hSTC810 demonstrated a favorable safety profile, with the most common adverse events being low-grade fatigue and infusion-related reactions onpmepbdmh (qhagvjxvtl ) View more | Positive | 30 Apr 2025 | ||
Phase 1 | Colonic Cancer BTN1A1 | 47 | (all cohorts) | msteywibuk(pyosmgwhyy) = nkzagqvegz ampcvjztru (qwreedwcku ) View more | Positive | 23 Jan 2025 | |
msteywibuk(pyosmgwhyy) = vhuufljkcw ampcvjztru (qwreedwcku ) View more | |||||||
Phase 1 | 12 | vjuhrwpxhy(pdnlpktdhu) = shxtifrkjc nufoiaiakw (vooxtvdsox ) | Positive | 23 Jan 2025 | |||
Phase 1 | Advanced Malignant Solid Neoplasm BTN1A1 | PD-L1 | 47 | hutoxmfbco(tnqsqnybbr) = showed a linear PK and consistent exposure qjpynlqfsk (sdiawjhsop ) | Positive | 05 Nov 2024 | ||
Phase 1 | 39 | STC810 | azuvhkesva(hrqdoeuopp) = gwkyrtifzh kikothvlnz (hfbbuphyyh ) View more | Positive | 26 May 2023 |
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Biosimilar
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Regulation
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