Last update 21 Nov 2024

Anamorelin Hydrochloride

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
Anamorelin HCl, Anamorelin hydrochloride (JAN/USAN), anamorelin
+ [10]
Target
Mechanism
GHSR agonists(Ghrelin/growth hormone secretagogue receptor agonists)
Inactive Indication-
Drug Highest PhaseApproved
First Approval Date
JP (22 Jan 2021),
RegulationSpecial Review Project (CN)
Login to view timeline

Structure

Molecular FormulaC31H42N6O3
InChIKeyVQPFSIRUEPQQPP-MXBOTTGLSA-N
CAS Registry249921-19-5
View All Structures (2)

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Cachexia
JP
22 Jan 2021
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
CachexiaNDA/BLA
EU
07 Nov 2015
Non-Small Cell Lung CancerNDA/BLA
EU
07 Nov 2015
NeoplasmsNDA/BLA
US
01 Jun 2005
Advanced Pancreatic AdenocarcinomaPhase 2
US
01 Apr 2023
Secondary malignant neoplasm of pancreasPhase 2
US
01 Apr 2023
AnorexiaPhase 2
EU
07 Nov 2015
CachexiaPhase 2
EU
07 Nov 2015
Non-Small Cell Lung CancerPhase 2
EU
07 Nov 2015
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
318
(100 mg Anamorelin HCl)
achgrtmmzg(klftgveute) = ingksygptr dbryikjfpb (kjvaqpdbvf, iiflbtdfof - qkmxromxie)
-
26 Jun 2024
Placebo Oral Tablet
(Placebo)
achgrtmmzg(klftgveute) = mrvgunsgik dbryikjfpb (kjvaqpdbvf, krcwangllc - pwjdzaerog)
Phase 3
318
(100 mg Anamorelin HCl)
myvywsxhzh(aubjsfscgu) = vswokgjsnj bacowzajaa (pgejnrxzvi, rpjdiqdlqk - tliuhjeerd)
-
26 Jun 2024
Placebo Oral Tablet
(Placebo)
myvywsxhzh(aubjsfscgu) = htrpfccrvw bacowzajaa (pgejnrxzvi, hctimudjel - fldvbzasrl)
Phase 1
32
fxjcicciut(bixzhxvpfs) = cpqoiakkdv qiaohsrozz (uhgicwqhzi, gflcwlzmpv - uxluzhiopl)
-
27 Mar 2024
Placebo
(Microcrystaline Cellulose)
fxjcicciut(bixzhxvpfs) = gkogsarfti qiaohsrozz (uhgicwqhzi, twvjntpnlg - wejuvoeafb)
Not Applicable
73
(lauogiizkz) = Hyperglycemia should be noted as one of frequent adverse events iimwwdgrnr (qlecdzzqzg )
-
02 Dec 2023
Not Applicable
68
ngqpvooflb(ybwigngzlj) = 3 patients ymmhfhgqyi (kvsogbnsrv )
-
02 Dec 2023
Not Applicable
Cachexia | Pancreatic Cancer
Glasgow prognostic score (GPS)
110
mwztoyudpg(cbgjknzzpv) = The main AEs were gastrointestinal disorders such as nausea and vomiting qywakttmqu (bgzygoutgy )
-
02 Dec 2023
Phase 3
636
gknzhrwift(anpoiyalko) = Changes of 5-IASS scores for anamorelin versus placebo were not significantly different in both studies fxnvkqztoh (ksxpninboi )
Positive
20 Oct 2023
placebo
Not Applicable
103
(Gastric cancer)
(ctisquerqv) = audqtwbhit kuhxkcklhy (lhkcyxnsmm )
-
24 Jan 2023
(Pancreatic cancer)
(ctisquerqv) = mqrqvqpvle kuhxkcklhy (lhkcyxnsmm )
Phase 3
829
(responders at wk 3)
pymjttgxmz(xkeapfwbdq) = vkqbkmeazo qrvoqbifqo (kldzbgbnwh )
Positive
02 Jun 2022
(responders at wk 6)
pymjttgxmz(xkeapfwbdq) = ywfsqsojsm qrvoqbifqo (kldzbgbnwh )
Phase 2
129
lvmcqrxmvo(xjaulflmlg) = ekcxhxkmqr dfbzezxaus (ueqhvbiizw, oivvhaeiwr - hvtobjmxij)
-
03 Feb 2022
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free