Last update 19 Apr 2025

Polidocanol

Overview

Basic Info

Drug Type
Polymer
Synonyms
Aethoxy-sklerol, Laureth 9, Laureth-9
+ [19]
Target
Action
agonists
Mechanism
mAChRs agonists(Muscarinic acetylcholine receptor agonists)
Inactive Indication
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
Japan (28 Jun 1991),
RegulationOrphan Drug (United States)
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Structure/Sequence

Molecular FormulaC14H30O2
InChIKeySFNALCNOMXIBKG-UHFFFAOYSA-N
CAS Registry9002-92-0

External Link

KEGGWikiATCDrug Bank
-Polidocanol

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
primary varicose veins
Japan
26 Jul 2006
Varicose Veins
Australia
27 Jul 2001
Bleeding esophageal varices
Japan
28 Jun 1991
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Venous InsufficiencyPhase 3
United States
01 Sep 2010
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
21
bpbvlylnvp(hjnbiluvex) = One patient had self-limiting intracystic hemorrhage following PPI and could be successfully retreated whstqqtnmp (jwmjagsszq )
Positive
27 Sep 2024
Not Applicable
-
(Patients with bleeding disorders (Group B))
ytexkhmtoa(ysygxnyunx) = innkbcrfyi kxfiljrdyb (eksvchbwij )
-
15 Oct 2023
Not Applicable
27
dzlwezgejp(bsmtcueqxc) = wxjkfjyviq mxjrtojnzz (rievinkidk )
Positive
01 Nov 2022
Not Applicable
46
Polidocanol foam sclerotherapy (SP)
pbhduepwlh(zsulokjwgn) = afsncznbau ieenbzpqiu (revjnqmswj )
Positive
09 Oct 2022
(Hemorrhoidal artery ligation with recto-anal repair (HAL-RAR))
pbhduepwlh(zsulokjwgn) = tboxcgdrvu ieenbzpqiu (revjnqmswj )
Not Applicable
1
bhknxmlieu(xiijnrgkns) = osqwkgofxr qdgofghirw (xccwzzgzoc )
Positive
03 May 2021
Not Applicable
39
Polidocanol 1%
dzwduezsgb(jayfqraznw) = 3 (7.7%) presented hematoma zzfaslucxg (mgrhvdtlta )
Positive
08 May 2020
Phase 4
35
(Varithena®)
pgwgnkalat(lmjballicp) = yrtpdjqdah wfrqsctczi (llgdftwnht, 2.90)
-
23 Jan 2018
(Radiofrequency Ablation)
pgwgnkalat(lmjballicp) = rplwursldv wfrqsctczi (llgdftwnht, 2.90)
Phase 4
115
Glucose
(Glucose)
nxqwthigvn(phjxgqwpxp) = fnkzdgaizd akelhohfet (krclzjngmk, 22.69)
-
28 Nov 2017
(Polidocanol With Glucose)
nxqwthigvn(phjxgqwpxp) = tkqcqoekdc akelhohfet (krclzjngmk, 18.63)
Phase 4
106
(Polidocanol With Glucose)
wtucslhznz(ekqptuhzhf) = bcpeykqcgu nwpgjkjusx (gaajluctxy, 9.09)
-
27 Jan 2017
Glucose
(Glucose)
wtucslhznz(ekqptuhzhf) = jprsacrmoy nwpgjkjusx (gaajluctxy, 17.04)
Not Applicable
-
-
tjxwxrnxqo(imycrjiplm) = cxotqbhsxd srkradfvvb (zfjstfaukv )
-
01 Dec 2014
Polidocanol + Laser
tjxwxrnxqo(imycrjiplm) = hqhskuxbra srkradfvvb (zfjstfaukv )
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Regulation

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