Last update 07 Dec 2024

Amtolmetin Guacil

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Amtolmetin, Amtolmetin guacil (INN), Amtolmetin-guacyl
+ [7]
Target
COX
Mechanism
COX inhibitors(Cyclooxygenases inhibitors)
Therapeutic Areas
Nervous System DiseasesOther Diseases
Active Indication
InflammationPain
Inactive Indication-
Originator Organization
Sigma-Tau Industrie Farmaceutiche Riunite SpASigma-Tau Industrie Farmaceutiche Riunite SpA
Active Organization
Sigma-Tau Industrie Farmaceutiche Riunite SpASigma-Tau Industrie Farmaceutiche Riunite SpA
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
IT (01 Jul 1995),
Inflammation
Regulation-
Login to view timeline

Structure

Molecular FormulaC24H24N2O5
InChIKeyCWJNMKKMGIAGDK-UHFFFAOYSA-N
CAS Registry87344-06-7

Related

1
Clinical Trials associated with Amtolmetin Guacil
NCT02865161 / CompletedNot Applicable
Open-label, Multicenter, Observational (Non-interventional) Study of Efficacy and Tolerability of Amtolmetin GuAcil in Subjects With Knee osTeoArthrosis With Dyspepsia. (AGATA)
100 Clinical Results associated with Amtolmetin Guacil
Login to view more data
100 Translational Medicine associated with Amtolmetin Guacil
Login to view more data
100 Patents (Medical) associated with Amtolmetin Guacil
Login to view more data
44
Literatures (Medical) associated with Amtolmetin Guacil
01 Dec 2022Annals of translational medicine
Comparison of cardiorenal safety of nonsteroidal anti-inflammatory drugs in the treatment of arthritis: a network meta-analysis
22 Mar 2016Arthritis
Amtolmetin: A Reappraisal of NSAID with Gastroprotection
01 Jan 2016Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
A choice of a nonsteroidal anti-inflammatory drug with regard to gastrointestinal and cardiovascular risks
100 Deals associated with Amtolmetin Guacil
Login to view more data

External Link

KEGGWikiATCDrug Bank
D07453Amtolmetin Guacil
M01AB03M02AA21
DB16088

R&D Status

10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Inflammation
IT
Sigma-Tau Industrie Farmaceutiche Riunite SpASigma-Tau Industrie Farmaceutiche Riunite SpA
01 Jul 1995
Pain---
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
EULAR2019
Not Applicable
Osteoarthritis | Rheumatoid Arthritis | Ankylosing Spondylitis
-
hoaoydtnqx(uhpddnhtjb) = The development or worsening of arterial hypertension, as well as other cardiovascular complications, was not observed fzqjpcmlnp (mvdkeuvpue )
View more
Positive
12 Jun 2019
EULAR2017
Not Applicable
Osteoarthritis, Knee
220
Amtolmetin guacil (AMG)
ktqtvkeakv(zwxkcwbfoc) = There were no serious adverse events (AE). AE were graded as moderate and mild in 8 and 82% of cases, respectively. AE were recorded in 7.7% of the patients. kqcgjzxorv (njsiepilkq )
View more
-
14 Jun 2017
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
login
or
view full example data
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
login
or
view full example data
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
login
or
view full example data
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
login
or
view full example data
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
login
or
view full example data
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
login
or
view full example data
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free