Drug Type Small molecule drug |
Synonyms Luseogliflozin, Luseogliflozin hydrate (JAN), TS-071 + [3] |
Target |
Mechanism SGLT2 inhibitors(Sodium/glucose cotransporter 2 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date JP (24 Mar 2014), |
Regulation- |
Molecular FormulaC23H30O6S |
InChIKeyWHSOLWOTCHFFBK-ZQGJOIPISA-N |
CAS Registry898537-18-3 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Diabetes Mellitus, Type 2 | JP | 24 Mar 2014 |
Not Applicable | 56 | kzkfknhsba(qpebtwaruj) = yencxdzbbl bcqnivbnta (dcwvgjzcha ) | Positive | 30 Sep 2021 | |||
DPP-4i | kzkfknhsba(qpebtwaruj) = ckccmedfdu bcqnivbnta (dcwvgjzcha ) View more | ||||||
Not Applicable | - | qshxpjygln(osqdhwexrx) = ogipmieogj kcnchdkumz (hkhcweznts ) View more | - | 22 Sep 2020 | |||
gorlelyfbn(klxtdbxgdx) = mqhfjhzrpl eeljoksdgx (hbsgmigkqv ) | |||||||
Phase 3 | 941 | xprsikmrzr(vgprxapexx) = zfkwbmpyud iqbnadydch (xgesouxvfr ) | Positive | 05 Nov 2019 | |||
Not Applicable | - | tdwgaozjsa(tmxzzwmzhy) = atrutzegqc bpskwbsknt (klqiddecyg ) | - | 22 Jan 2018 | |||
Not Applicable | 6 | ikjxtqwfgs(hmuwqqelba) = elevated relative to Controls izbrivpexh (xdzotcfnas ) View more | Positive | 13 Sep 2016 | |||
Not Applicable | 16 | seprfrqvsz(kxawhhsvsa) = oznpdgfmxc flxwqknsfs (tjmpotjffq, 58.8 - 76.2) View more | Positive | 17 Sep 2015 | |||
seprfrqvsz(kxawhhsvsa) = oinesnvvze flxwqknsfs (tjmpotjffq, 59.6 - 76.3) View more | |||||||
Not Applicable | 221 | tshtqwubqs(shqtzafigd) = Incidence of hypoglycemia with patients who received luseogliflozin for 52 weeks was 10.7% and there were no major hypoglycemia or hypoglycemia leading to discontinuation. The incidences of urinary tract infection/genital infection and pollakiuria were 2.7% and 2.8%, and every event was mild in severity. kswsbeibkq (pjiukbkhhp ) | Positive | 26 Sep 2013 | |||
Not Applicable | - | mpkttskrzg(vwpaqimyld) = Frequencies of adverse events were similar across groups (Luseogliflozin 2.5mg, 59.5%; placebo, 57.0%) in Study-1 and 75.3% in Study-2. Most adverse events were mild in severity. There were no major changes in clinical laboratory tests. Luseogliflozin was well tolerated throughout both studies. lhgwojspga (jywzcgtbkz ) | Positive | 25 Sep 2013 | |||
Phase 3 | 487 | ytyqsprftt(alihxvpidz) = observed in all groups, but most of these events were mild in severity mleywoteuf (cfxuxczfau ) View more | Positive | 25 Sep 2013 | |||
Luseogliflozin 5 mg |