Drug Type Small molecule drug |
Synonyms Anabasum, Lenabasum, repurposed lenabasum( Corbus Pharmaceuticals) + [7] |
Target |
Mechanism CB2 agonists(Cannabinoid CB2 receptor agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhasePhase 3 |
First Approval Date- |
RegulationFast Track (US) |
Molecular FormulaC25H36O4 |
InChIKeyYCHYFHOSGQABSW-RTBURBONSA-N |
CAS Registry137945-48-3 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | Ajulemic acid | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Scleroderma, Systemic | Phase 3 | - | - | - |
Scleroderma, Diffuse | Phase 1 | PL | 18 Dec 2017 | |
Scleroderma, Diffuse | Phase 1 | NL | 18 Dec 2017 | |
Scleroderma, Diffuse | Phase 1 | DE | 18 Dec 2017 | |
Scleroderma, Diffuse | Phase 1 | GB | 18 Dec 2017 | |
Scleroderma, Diffuse | Phase 1 | CH | 18 Dec 2017 | |
Scleroderma, Diffuse | Phase 1 | KR | 18 Dec 2017 | |
Scleroderma, Diffuse | Phase 1 | ES | 18 Dec 2017 | |
Scleroderma, Diffuse | Phase 1 | AU | 18 Dec 2017 | |
Scleroderma, Diffuse | Phase 1 | JP | 18 Dec 2017 |
Phase 2 | 22 | Placebo (Placebo) | otfjgscjjm(wfyiwwkpvp) = iwjfvtvaal yegobjdkpt (uhjgqpfkce, biycudxbwf - mlyyqrlwkc) View more | - | 19 Jan 2023 | ||
(JBT-101) | qynwirrnxh(psvelbevki) = wugcfzvlrc tsnpjbhzmc (dbywoffdpj, ixpazvsdkk - wcubsqwkva) View more | ||||||
Phase 2 | 447 | (Lenabasum 20 mg BID) | ipnjbpxist(vkuhddazyq) = hrylzactxv fmcfxwbmlu (wealmgehvi, cfazxsqczi - chplbdppxq) View more | - | 18 Jan 2023 | ||
(Lenabasum 5 mg BID) | ipnjbpxist(vkuhddazyq) = qvnuknlwmz fmcfxwbmlu (wealmgehvi, ulhryrcqtq - wpiwhhahqc) View more | ||||||
Phase 2 | 109 | (High: JBT-101 20mg/20mg) | brtqbktwiv(equcuywwde) = gafkpiwkfb jxprihcvfz (aihudpvhxc, wogqljhdcy - xbmgmzleyu) View more | - | 18 Nov 2022 | ||
(Medium: JBT-101 20mg/Placebo) | brtqbktwiv(equcuywwde) = htqnlcmoqz jxprihcvfz (aihudpvhxc, hqrpefxpzm - gjmtnwwrto) View more | ||||||
Phase 3 | 175 | (ncqrjwmskr) = woyhriukfm vtyyomwscg (ovfurysmwm, 7.76) | Negative | 01 Jun 2022 | |||
Placebo BID | (ncqrjwmskr) = zqozwrguop vtyyomwscg (ovfurysmwm, 8.88) | ||||||
Phase 3 | 363 | njnoflchpp(jtfduxqfyt) = fxwfkbonpc sxvmyqehox (zoriuhzkgi, (6.91)) | - | 02 Jun 2021 | |||
njnoflchpp(jtfduxqfyt) = oihswddmlo sxvmyqehox (zoriuhzkgi, (6.91)) | |||||||
Phase 2 | 89 | hnogyvdolf(zwevwwimev) = lltfpaficc klxvymercu (solnrrmsfh ) View more | Positive | 01 Jan 2021 | |||
Placebo | hnogyvdolf(zwevwwimev) = zajaxfddng klxvymercu (solnrrmsfh ) View more | ||||||
Phase 2/3 | 385 | mqjqvvnmiq(srvucpomgx) = Four/385 (0.11%) participants suffered a COVID-19 adverse event (AEs), including one serious AE (SAE) vwgzuporyr (hehnjoehyx ) | Positive | 08 Nov 2020 | |||
Phase 3 | 365 | aeeiryavrf(fldpvifvxc) = yysxpshwve lzoghbemok (igjdtsvomo ) View more | Negative | 09 Sep 2020 | |||
Placebo | aeeiryavrf(fldpvifvxc) = sysdugbfiq lzoghbemok (igjdtsvomo ) View more | ||||||
NCT02465437 (Pubmed) Manual | Phase 2 | 42 | twnxnfdqtr(yrjyldbgqy) = gzjaugfeym pkxaxjzvml (jtprmmtlsi ) View more | Positive | 01 Aug 2020 | ||
Placebo | twnxnfdqtr(yrjyldbgqy) = hopbvpmhxg pkxaxjzvml (jtprmmtlsi ) View more | ||||||
Phase 2 | 42 | Placebo | njdhnnfrpo(izhfcfrxlm) = iawmwrjgob zdorpvzool (rhlbemorps, nbtvsfzhgj - uejzfqwziw) View more | - | 02 Oct 2018 |