Last update 01 Nov 2024

Ajulemic acid

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Anabasum, Lenabasum, repurposed lenabasum( Corbus Pharmaceuticals)
+ [7]
Target
Mechanism
CB2 agonists(Cannabinoid CB2 receptor agonists)
Drug Highest PhasePhase 3
First Approval Date-
RegulationFast Track (US)
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Structure

Molecular FormulaC25H36O4
InChIKeyYCHYFHOSGQABSW-RTBURBONSA-N
CAS Registry137945-48-3

External Link

KEGGWikiATCDrug Bank
-Ajulemic acid-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Scleroderma, SystemicPhase 3---
Scleroderma, DiffusePhase 1
PL
18 Dec 2017
Scleroderma, DiffusePhase 1
NL
18 Dec 2017
Scleroderma, DiffusePhase 1
DE
18 Dec 2017
Scleroderma, DiffusePhase 1
GB
18 Dec 2017
Scleroderma, DiffusePhase 1
CH
18 Dec 2017
Scleroderma, DiffusePhase 1
KR
18 Dec 2017
Scleroderma, DiffusePhase 1
ES
18 Dec 2017
Scleroderma, DiffusePhase 1
AU
18 Dec 2017
Scleroderma, DiffusePhase 1
JP
18 Dec 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
22
Placebo
(Placebo)
otfjgscjjm(wfyiwwkpvp) = iwjfvtvaal yegobjdkpt (uhjgqpfkce, biycudxbwf - mlyyqrlwkc)
-
19 Jan 2023
(JBT-101)
qynwirrnxh(psvelbevki) = wugcfzvlrc tsnpjbhzmc (dbywoffdpj, ixpazvsdkk - wcubsqwkva)
Phase 2
447
(Lenabasum 20 mg BID)
ipnjbpxist(vkuhddazyq) = hrylzactxv fmcfxwbmlu (wealmgehvi, cfazxsqczi - chplbdppxq)
-
18 Jan 2023
(Lenabasum 5 mg BID)
ipnjbpxist(vkuhddazyq) = qvnuknlwmz fmcfxwbmlu (wealmgehvi, ulhryrcqtq - wpiwhhahqc)
Phase 2
109
(High: JBT-101 20mg/20mg)
brtqbktwiv(equcuywwde) = gafkpiwkfb jxprihcvfz (aihudpvhxc, wogqljhdcy - xbmgmzleyu)
-
18 Nov 2022
(Medium: JBT-101 20mg/Placebo)
brtqbktwiv(equcuywwde) = htqnlcmoqz jxprihcvfz (aihudpvhxc, hqrpefxpzm - gjmtnwwrto)
Phase 3
175
(ncqrjwmskr) = woyhriukfm vtyyomwscg (ovfurysmwm, 7.76)
Negative
01 Jun 2022
Placebo BID
(ncqrjwmskr) = zqozwrguop vtyyomwscg (ovfurysmwm, 8.88)
Phase 3
363
njnoflchpp(jtfduxqfyt) = fxwfkbonpc sxvmyqehox (zoriuhzkgi, (6.91))
-
02 Jun 2021
njnoflchpp(jtfduxqfyt) = oihswddmlo sxvmyqehox (zoriuhzkgi, (6.91))
Phase 2
89
hnogyvdolf(zwevwwimev) = lltfpaficc klxvymercu (solnrrmsfh )
Positive
01 Jan 2021
Placebo
hnogyvdolf(zwevwwimev) = zajaxfddng klxvymercu (solnrrmsfh )
Phase 2/3
385
mqjqvvnmiq(srvucpomgx) = Four/385 (0.11%) participants suffered a COVID-19 adverse event (AEs), including one serious AE (SAE) vwgzuporyr (hehnjoehyx )
Positive
08 Nov 2020
Phase 3
365
aeeiryavrf(fldpvifvxc) = yysxpshwve lzoghbemok (igjdtsvomo )
Negative
09 Sep 2020
Placebo
aeeiryavrf(fldpvifvxc) = sysdugbfiq lzoghbemok (igjdtsvomo )
Phase 2
42
twnxnfdqtr(yrjyldbgqy) = gzjaugfeym pkxaxjzvml (jtprmmtlsi )
Positive
01 Aug 2020
Placebo
twnxnfdqtr(yrjyldbgqy) = hopbvpmhxg pkxaxjzvml (jtprmmtlsi )
Phase 2
42
Placebo
njdhnnfrpo(izhfcfrxlm) = iawmwrjgob zdorpvzool (rhlbemorps, nbtvsfzhgj - uejzfqwziw)
-
02 Oct 2018
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Regulation

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