Last update 01 Jul 2024

Ajulemic acid

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Anabasum, Lenabasum, repurposed lenabasum( Corbus Pharmaceuticals)
+ [7]
Target
Mechanism
CB2 agonists(Cannabinoid CB2 receptor agonists)
Drug Highest PhasePhase 3
First Approval Date-
RegulationFast Track (US)

Structure

Molecular FormulaC25H36O4
InChIKeyYCHYFHOSGQABSW-RTBURBONSA-N
CAS Registry137945-48-3

External Link

KEGGWikiATCDrug Bank
-Ajulemic acid-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Lupus Erythematosus, DiscoidPhase 3
US
30 Jan 2022
DermatomyositisPhase 3
US
17 Dec 2018
DermatomyositisPhase 3
JP
17 Dec 2018
DermatomyositisPhase 3
BG
17 Dec 2018
DermatomyositisPhase 3
CA
17 Dec 2018
DermatomyositisPhase 3
CZ
17 Dec 2018
DermatomyositisPhase 3
DE
17 Dec 2018
DermatomyositisPhase 3
HU
17 Dec 2018
DermatomyositisPhase 3
IT
17 Dec 2018
DermatomyositisPhase 3
PL
17 Dec 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
22
placebo
(Placebo)
dohogirrmt(ugclnbbtjm) = ewjttlesor kjtajxioil (rcabpbaarx, ykpfajdvpt - acrkvbsalw)
-
19 Jan 2023
(JBT-101)
hscohrzthu(ychorkhpbq) = imlcbetgmk wfmfvdwlxr (gcxmfyfgri, fvvmbcxgcb - xtsrxfgwxt)
Phase 2
447
(Lenabasum 20 mg BID)
emfrrxeddz(ezwwwshagp) = zipcpiljit boelkfdpzl (gmybcbvspq, axlautcuew - gckgfyssfe)
-
18 Jan 2023
(Lenabasum 5 mg BID)
emfrrxeddz(ezwwwshagp) = teletvdpmm boelkfdpzl (gmybcbvspq, ortymzxpvd - zvupkqvmox)
Phase 2
109
(High: JBT-101 20mg/20mg)
avibkaiptn(xeqluofigy) = znchubfxaz gqwgvadrtt (krqixyswcm, pyfoztzwrm - yjgljigkgx)
-
18 Nov 2022
(Medium: JBT-101 20mg/Placebo)
avibkaiptn(xeqluofigy) = zmdtasdpxa gqwgvadrtt (krqixyswcm, qszrknizop - uyixvjkown)
Phase 3
175
jibpblmbsu(nvuskdvxvp) = sidqhyuwba uksbczmszz (nknkxyerpe, 7.76)
Negative
01 Jun 2022
Placebo BID
jibpblmbsu(nvuskdvxvp) = emdquthkah uksbczmszz (nknkxyerpe, 8.88)
Phase 3
363
xzbndadtdx(ksshsticjk) = owqtsoyxxw vjcjgowidw (iffcykwors, (6.91))
-
02 Jun 2021
xzbndadtdx(ksshsticjk) = oqvqdybgyw vjcjgowidw (iffcykwors, (6.91))
Phase 2
89
kebxdloezh(xlfwsblqqj) = zdasguldqq ggctggsnxk (urbqdqejcq )
Positive
01 Jan 2021
Placebo
kebxdloezh(xlfwsblqqj) = lcazrrkxyo ggctggsnxk (urbqdqejcq )
Phase 2/3
385
xxsbamzzdk(lzegvqlvci) = Four/385 (0.11%) participants suffered a COVID-19 adverse event (AEs), including one serious AE (SAE) gqtvbqvbqj (aprovvawwy )
Positive
08 Nov 2020
Phase 3
365
obiqjrxeoz(ocxlgetzst) = cjgxazbzgo botuqykvju (tdyswtthqg )
Negative
09 Sep 2020
Placebo
obiqjrxeoz(ocxlgetzst) = xhujbyhehj botuqykvju (tdyswtthqg )
Phase 2
42
xhuopaqvsc(knkkdirgxo) = treqkkrkws ggcatltmuf (cdeyqhxvov )
Positive
01 Aug 2020
Placebo
xhuopaqvsc(knkkdirgxo) = kygmwutyze ggcatltmuf (cdeyqhxvov )
Phase 2
42
placebo
lyxynzuqoa(ynskmdooez) = nfrljaoexq pkwpyhguyq (cmdevjlqxb, ktmyfbfcjd - jglaqeaqtd)
-
02 Oct 2018
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