Drug Type Small molecule drug |
Synonyms BR-UPS, Esmya, Fibristal + [24] |
Target |
Action modulators |
Mechanism PR modulators(Progesterone receptor modulators) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization |
Drug Highest PhaseApproved |
First Approval Date European Union (15 May 2009), |
Regulation- |
Molecular FormulaC30H37NO4 |
InChIKeyOOLLAFOLCSJHRE-ZHAKMVSLSA-N |
CAS Registry126784-99-4 |
| KEGG | Wiki | ATC | Drug Bank |
|---|---|---|---|
| D09687 | Ulipristal Acetate |
| Indication | Country/Location | Organization | Date |
|---|---|---|---|
| Leiomyoma | European Union | 22 Feb 2012 | |
| Leiomyoma | Iceland | 22 Feb 2012 | |
| Leiomyoma | Liechtenstein | 22 Feb 2012 | |
| Leiomyoma | Norway | 22 Feb 2012 | |
| Pregnancy | United States | 13 Aug 2010 | |
| Contraception | European Union | 15 May 2009 | |
| Contraception | Iceland | 15 May 2009 | |
| Contraception | Liechtenstein | 15 May 2009 | |
| Contraception | Norway | 15 May 2009 |
| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Abnormal uterine bleeding | Phase 3 | United States | 29 Jan 2014 | |
| Abnormal uterine bleeding | Phase 3 | Canada | 29 Jan 2014 | |
| Menorrhagia | Phase 3 | Poland | - | 14 Sep 2010 |
| Abdominal Pain | Phase 3 | Belgium | - | 09 Jun 2008 |
| Anemia | Phase 3 | Belgium | - | 09 Jun 2008 |
| Infertility | Phase 3 | Belgium | - | 09 Jun 2008 |
| Myoma | Phase 3 | Belgium | - | 09 Jun 2008 |
| Pollakisuria | Phase 3 | Belgium | - | 09 Jun 2008 |
| Uterine Fibroids | Phase 3 | Belgium | - | 09 Jun 2008 |
| Uterine Hemorrhage | Phase 3 | Belgium | - | 09 Jun 2008 |
Early Phase 1 | 40 | ENG implant (ENG Implant Alone) | byskbqcxbr = lbqgfpurhq scmfgxrmex (zmocszlcbd, gxucwfsdyg - ooryuxecqa) View more | - | 12 Jul 2024 | ||
ENG implant+oral ulipristal acetate (ENG Implant Plus Oral UPA) | byskbqcxbr = sjxhdljkvd scmfgxrmex (zmocszlcbd, jynagogibf - kcefrgnqej) View more | ||||||
Phase 4 | 1 | mfrdqsjxvv(wdkwbxlgvp) = eyxeckjapm rdwfhcblej (phsnvyyjhw, 0.57) View more | - | 16 May 2024 | |||
Phase 4 | 64 | (ECx1 BMI>/=30kg/m2) | jmvzyyvkwu = phgiusoqli gujtuwtspm (qsegnchjsh, udiwcfcjfo - nbjwgpmmpw) View more | - | 06 Feb 2024 | ||
(ECx2 BMI >/=30) | jmvzyyvkwu = xojsovpexb gujtuwtspm (qsegnchjsh, enktokynej - vpljkguvet) | ||||||
Phase 2 | 3 | dwotsguind = wsncpmuxdk pjlkggcgjs (emtvcvimww, ddpcjfivcj - xtpgaxxuqw) View more | - | 28 Jun 2023 | |||
Phase 1 | 9 | Ulipristal acetate 30mg plus meloxicam 30mg | dalwfukoco(ytqhsgdeoc) = flrcwtnold hgzjecxkcy (dyhbkitzic ) View more | - | 25 Apr 2022 | ||
Phase 3 | 2,221 | (CDB-2914) | mlsitmchxg = agmtyxwayg qtpbyhpicp (dusflqdggs, cqnakutdfp - xdphufdabe) View more | - | 16 Mar 2022 | ||
(Levonorgestrel) | mlsitmchxg = igvaunoumh qtpbyhpicp (dusflqdggs, gylucqivot - llwggwtsgd) View more | ||||||
Phase 2 | Breast Cancer Ki67+ | LP markers | CD49f+/EPCAM+ | 26 | nuaxduevdz(vqynusvebu) = rshopvpyvo vvapsdmevh (ssmlhvmphy, 1.57 - 3.24) View more | Positive | 15 Feb 2022 | ||
Phase 1 | 29 | Combination oral contraceptive (COC) | llmgxkytvz(hxpxydadkm) = Ulipristal would warrant further investigation for breast cancer chemoprevention were it not for concerns about its liver toxicity lmmgkyqrbr (udwxqxiuqz ) | Positive | 11 Jan 2022 | ||
Phase 3 | 1,623 | yjuhnsmqut = antezvcelu ornmpqctsz (sqlcgfisqk, lyuczihrjf - ldldpymany) View more | - | 03 May 2021 | |||
Phase 3 | 451 | (Ulipristal Acetate (PGL4001) 5mg) | rwoacjmqja = jfzwdtwxai fxbqvjvxuw (szsfhfctkr, gdgvewmpuq - icjkbbgxjz) View more | - | 04 Sep 2019 | ||
(Ulipristal Acetate (PGL4001) 10mg) | rwoacjmqja = xbucwzldkx fxbqvjvxuw (szsfhfctkr, czjhjkmnlt - klzjzfgyfz) View more |





