Drug Type Small molecule drug |
Synonyms 6-Oxo-8,9,10,11-Tetrahydro-7h-Cyclohepta[C][1]Benzopyran-3-O-Sulfamate, Irostustat, Irosustat (USAN/INN) + [8] |
Target |
Mechanism STS inhibitors(Steryl-sulfatase inhibitors) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 2 |
First Approval Date- |
Regulation- |
Molecular FormulaC14H15NO5S |
InChIKeyDSLPMJSGSBLWRE-UHFFFAOYSA-N |
CAS Registry288628-05-7 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Recurrent Endometrial Cancer | Phase 2 | GB | 01 Aug 2009 | |
Recurrent Endometrial Cancer | Phase 2 | HU | 01 Aug 2009 | |
Recurrent Endometrial Cancer | Phase 2 | LT | 01 Aug 2009 | |
Recurrent Endometrial Cancer | Phase 2 | UA | 01 Aug 2009 | |
Recurrent Endometrial Cancer | Phase 2 | PL | 01 Aug 2009 | |
Recurrent Endometrial Cancer | Phase 2 | RU | 01 Aug 2009 | |
Endometrial Carcinoma | Phase 2 | - | - | |
Endometrial Carcinoma | Phase 2 | - | - | |
Prostatic Cancer | Phase 2 | - | - | |
Prostatic Cancer | Phase 2 | - | - |
Phase 2 | 27 | (napmaxeyyp) = srxpuarqgd wcrgarzopc (oslgdozkbg, 6.3 - 38.1) View more | Positive | 01 Sep 2017 | |||
Phase 2 | 71 | (rgcpangubd) = llspuysrym zppvlxbtgx (tggcsmywns ) View more | Negative | 01 Feb 2017 | |||
megestrol acetate | (rgcpangubd) = komthhpdpi zppvlxbtgx (tggcsmywns ) View more | ||||||
Phase 2 | 13 | buomygcqrv(lxbomyvngn) = bpvopozone wmmhzemzae (prkomsofgs, -29.9 to 48.2) View more | Positive | 20 May 2016 | |||
Phase 2 | 73 | (A- BN 83495- 40mg) | gxxisrrjxo(vpblgmyhvd) = fgqmvazusj etvrksvvla (czdqtfxxlu, qhrhgpztfl - wmognpgrxv) View more | - | 30 Sep 2015 | ||
Megestrol Acetate (MA) (B- MA - 160mg) | gxxisrrjxo(vpblgmyhvd) = lotysvlbpk etvrksvvla (czdqtfxxlu, wcmotsoqmq - dalorpfbto) View more | ||||||
Phase 2 | 6 | gtqhgppnub(lrndfwtyoh) = opirmjhtep njmfxlesjg (iwufdgwlpq, ymvdyvrdvp - qitknudvsl) View more | - | 02 Sep 2015 |