Drug Type Small molecule drug |
Synonyms 6-Oxo-8,9,10,11-Tetrahydro-7h-Cyclohepta[C][1]Benzopyran-3-O-Sulfamate, Irostustat, Irosustat (USAN/INN) + [8] |
Target |
Action inhibitors |
Mechanism STS inhibitors(Steryl-sulfatase inhibitors) |
Therapeutic Areas |
Active Indication- |
Originator Organization |
Active Organization- |
Inactive Organization |
License Organization- |
Drug Highest PhaseDiscontinuedPhase 2 |
First Approval Date- |
Regulation- |
Molecular FormulaC14H15NO5S |
InChIKeyDSLPMJSGSBLWRE-UHFFFAOYSA-N |
CAS Registry288628-05-7 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Estrogen receptor positive breast cancer | Phase 2 | Norway | 01 May 2011 | |
ER Positive Endometrial Carcinoma | Phase 2 | United States | 01 Nov 2010 | |
ER Positive Endometrial Carcinoma | Phase 2 | Canada | 01 Nov 2010 | |
Recurrent Endometrial Cancer | Phase 2 | United States | 01 Aug 2009 | |
Recurrent Endometrial Cancer | Phase 2 | Belgium | 01 Aug 2009 | |
Recurrent Endometrial Cancer | Phase 2 | Czechia | 01 Aug 2009 | |
Recurrent Endometrial Cancer | Phase 2 | France | 01 Aug 2009 | |
Recurrent Endometrial Cancer | Phase 2 | Hungary | 01 Aug 2009 | |
Recurrent Endometrial Cancer | Phase 2 | Latvia | 01 Aug 2009 | |
Recurrent Endometrial Cancer | Phase 2 | Lithuania | 01 Aug 2009 |
Phase 2 | 27 | ariigumooz(sdqwzyhyoy) = yvglcpgspy qsxvngkndg (uzlynguleu, 6.3 - 38.1) View more | Positive | 01 Sep 2017 | |||
Phase 2 | 71 | qthocuomyc(jukdyujvbx) = yhsgqponbr gijeqwllmu (bbctqefzin ) View more | Negative | 01 Feb 2017 | |||
qthocuomyc(jukdyujvbx) = vyvbzkxlfv gijeqwllmu (bbctqefzin ) View more | |||||||
Phase 2 | 13 | jlfvflwtgn(cjfzbwhnpe) = qtzigymtpn cdemgnelss (zfjiymrlpu, -29.9 to 48.2) View more | Positive | 20 May 2016 | |||
Phase 2 | Estrogen receptor positive breast cancer First line | 27 | Irosustat + AI | zrrsttxxfv(ubhuiwbysu) = 7% gubqfoezch (actoaiojrk ) View more | Positive | 20 May 2016 | |
Phase 2 | 73 | (A- BN 83495- 40mg) | xmixnnjneh(fjvdfdvjyq) = niecqannzf xctzfiyubw (bzviradlrt, rwsvqiawkx - ydqddoxlnx) View more | - | 30 Sep 2015 | ||
(B- MA - 160mg) | xmixnnjneh(fjvdfdvjyq) = ytmcisrcui xctzfiyubw (bzviradlrt, lntxayidln - liliqfocrh) View more | ||||||
Phase 2 | 6 | hoskcclbug = odwcozxmvw yqmpcoryub (bozvqzpxdx, cwlrnjqxfr - izucgwgthm) View more | - | 02 Sep 2015 |