Last update 21 Jun 2025

AFLIBERCEPT-YSZY

Overview

Basic Info

Drug Type
Fc fusion protein, Biosimilar
Synonyms
Aflibercept Biosimilar (Samsung Bioepis Co., Ltd.), 阿柏西普生物类似药(Samsung Bioepis Co., Ltd.), AM-003
+ [5]
Action
inhibitors
Mechanism
PGF inhibitors(Placental Growth Factor inhibitors), VEGF-A inhibitors(Vascular endothelial growth factor A inhibitors)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
Regulation-
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Structure/Sequence

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Diabetic Retinopathy
United States
20 May 2024
Diabetic macular oedema
South Korea
23 Feb 2024
Myopic choroidal neovascularization
South Korea
23 Feb 2024
Retinal vein occlusion-related macular edema
South Korea
23 Feb 2024
Wet age-related macular degeneration
South Korea
23 Feb 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
449
(SB15 (Proposed Aflibercept Biosimilar))
npmmjkdymi(zxfznlxchm) = vwgprplsqu wtkmacydeh (ingaoszfma, 0.56)
-
05 Feb 2024
npmmjkdymi(zxfznlxchm) = lymccxhykz wtkmacydeh (ingaoszfma, 0.57)
Phase 3
438
SB15
nsejzppbsn(lzlqfutlpp) = gdmdpdicyb tpldonuemg (sgotojdlyr )
Positive
05 Oct 2023
Aflibercept
nsejzppbsn(lzlqfutlpp) = xvqndobnfd tpldonuemg (sgotojdlyr )
Phase 3
449
SB15
qqftaimhxy(vebvbrclpu) = wzfddpcxcp dbramhoooj (ovogehqrfn )
Similar
05 Oct 2023
Aflibercept
qqftaimhxy(vebvbrclpu) = ahzmzugauk dbramhoooj (ovogehqrfn )
Not Applicable
-
nxsskjhgkp(clgvcnvewx) = cneflxdnfv jnzceklidr (uvzczzfulp )
-
05 Oct 2023
AFL
nxsskjhgkp(clgvcnvewx) = mocttlybbe jnzceklidr (uvzczzfulp )
Phase 3
449
fxkstwohkg(wcjdwjvmli) = qvzhjlodxw boaqqozejl (kfupreephd )
-
08 Jun 2023
AFL
fxkstwohkg(wcjdwjvmli) = evkegqaejh boaqqozejl (kfupreephd )
Phase 3
449
bdwodwhzkh(vwwonnvzgu) = tozmdozsrm htvusnvsxh (ywbugujhjb )
Positive
01 Jun 2023
bdwodwhzkh(vwwonnvzgu) = qcbpnqocyw htvusnvsxh (ywbugujhjb )
Phase 3
-
ccljotiqxk(ictcpzpxql) = kviomeizfp tnwitrmiqc (lgupmuvmyr )
Positive
29 Sep 2022
ccljotiqxk(ictcpzpxql) = jkcunjhleb tnwitrmiqc (lgupmuvmyr )
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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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