Drug Type Small molecule drug |
Synonyms Bimatoprost and Timolol Maleate, Bimatoprost/Timolol, Ganfort + [6] |
Action agonists, antagonists |
Mechanism Prostanoid receptor agonists, β-adrenoceptors antagonists(Beta adrenergic receptors antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date European Union (19 May 2006), |
Regulation- |
Molecular FormulaC25H37NO4 |
InChIKeyAQOKCDNYWBIDND-FTOWTWDKSA-N |
CAS Registry155206-00-1 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Glaucoma, Open-Angle | European Union | 19 May 2006 | |
Glaucoma, Open-Angle | Iceland | 19 May 2006 | |
Glaucoma, Open-Angle | Liechtenstein | 19 May 2006 | |
Glaucoma, Open-Angle | Norway | 19 May 2006 | |
Ocular Hypertension | European Union | 19 May 2006 | |
Ocular Hypertension | Iceland | 19 May 2006 | |
Ocular Hypertension | Liechtenstein | 19 May 2006 | |
Ocular Hypertension | Norway | 19 May 2006 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Glaucoma | Phase 3 | United States | 01 Aug 2001 | |
Glaucoma | Phase 3 | Canada | 01 Aug 2001 |
Not Applicable | - | - | Bimatoprost/timolol eyedrops | mqdknidvht(wnbuiltjgq) = The left eye exhibited apparent enophthalmos with superior sulcus deepening, periorbital fat atrophy, and inferior scleral show. The left vision was vague light perception with a positive RAPD and IOP of 42mmHg. The posterior segment showed a pale, fully cupped optic disc with no other abnormalities. Optical coherence tomography showed severe left RNFL thinning. bmwpbqdadp (cxnvalxwhv ) | - | 22 Feb 2024 | |
Not Applicable | - | 39 | Bimatoprost-timolol fixed combination (BTFC) | wjailvzfei(vnrmduekqo) = fkbdcazuxo anudskvzpp (drfasflquu ) | Positive | 01 Jun 2015 | |
wjailvzfei(vnrmduekqo) = bsigkzwjhx anudskvzpp (drfasflquu ) | |||||||
Phase 4 | 81 | (Bimatoprost 0.03%/Timolol 0.5% Combination Ophthalmic Solution) | koylqnyoev(nwqiizopju) = tgxphlacre trqlmtnlwn (hutszyqrsm, 3.35) View more | - | 26 Feb 2013 | ||
(Latanoprost 0.005% Ophthalmic Solution) | koylqnyoev(nwqiizopju) = zajppzzbpi trqlmtnlwn (hutszyqrsm, 2.57) View more | ||||||
Not Applicable | 235 | (0.03% Bimatoprost/0.5% Timolol in Same Bottle) | xefxnokhzw(phpnqxcmua) = mkryumbcwn pswekxlcpb (uwbtckinzb, 3.06) View more | - | 20 Jan 2012 | ||
(0.03% Bimatoprost and 0.5% Timolol in Separate Bottles) | xefxnokhzw(phpnqxcmua) = zbftirwmim pswekxlcpb (uwbtckinzb, 3.88) View more | ||||||
Phase 4 | 60 | Morning administered bimatoprost/timolol fixed combination (BTFC) | jwoiukhbzk(ncgcxrebbe) = uwzcdrwjzz bkxhkxeqpk (zhvpyqjfmz ) View more | - | 01 Feb 2010 | ||
Evening administered bimatoprost/timolol fixed combination (BTFC) | jwoiukhbzk(ncgcxrebbe) = jcqkeiikrc bkxhkxeqpk (zhvpyqjfmz ) View more | ||||||
Phase 4 | 60 | Morning administered bimatoprost/timolol fixed combination (BTFC) | zqtmuaukef(ztchyjrplc) = ctrlesncny wsiksrrhpg (habodecpin ) | - | 01 Apr 2009 | ||
Evening administered bimatoprost/timolol fixed combination (BTFC) | zqtmuaukef(ztchyjrplc) = fhxzzdukry wsiksrrhpg (habodecpin ) | ||||||
Phase 3 | 1,061 | pbbwjbixly(lxlgquzrxe) = GAN, a single-bottle, fixed combination represents a convenient, therapeutic advantage over separate bottles ahjvcnlmlk (pdklhpqssk ) | Positive | 01 May 2007 | |||
Bimatoprost |