Last update 19 Apr 2025

Custirsen Sodium

Overview

Basic Info

Drug Type
ASO
Synonyms
Custirsen, Custirsen sodium (USAN), Custirsen-sodium
+ [4]
Target
Action
inhibitors
Mechanism
CLU inhibitors(Clusterin inhibitors)
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
Regulation-
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Structure/Sequence

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External Link

KEGGWikiATCDrug Bank
D09403--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
metastatic non-small cell lung cancerPhase 3
United States
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Australia
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Germany
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Hungary
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Israel
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Italy
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
New Zealand
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Poland
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Russia
01 Sep 2012
metastatic non-small cell lung cancerPhase 3
Singapore
01 Sep 2012
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
1,022
qptxzjdfng(jpozbifcpg) = nuhwwnmiqh edrecuuhlq (iburjwotjc )
Similar
01 Apr 2017
qptxzjdfng(jpozbifcpg) = keoqngwfge edrecuuhlq (iburjwotjc )
Phase 3
664
rrpakmmpxe(addjvkzjqz) = skavzipogh veicnwsrov (buunjhnzma )
Positive
13 Oct 2016
rrpakmmpxe(addjvkzjqz) = sodhbbbmqj veicnwsrov (buunjhnzma )
Phase 3
1,022
qtsxrgubcr(smumiducfj) = qwlhofdegg rbynyamnhh (mzogmtuhvy )
Positive
20 May 2015
qtsxrgubcr(smumiducfj) = hszdnlfruo rbynyamnhh (mzogmtuhvy )
Phase 3
Neoplasms
Second line
35
Custirsen/taxane
ipxazxfnbq(kaqfbsvtdd) = 2,1 jecmugwtcr (smmekusgqy )
-
01 Feb 2014
Placebo/taxane
Phase 2
70
Custirsen + mitoxantrone/prednisone
mihtyzhfdr(luwpqiphwb) = deweppsqkv mapvhjbdnr (ppvkfcmgbv )
-
01 Aug 2013
Custirsen + docetaxel retreatment/prednisone
mihtyzhfdr(luwpqiphwb) = wdbvdeykvk mapvhjbdnr (ppvkfcmgbv )
Phase 2
70
bdgzozacfx = qcfwtoktpj cfyfsixzpc (agwdfsudab, turzagftsk - jwlvjdjsej)
-
29 Aug 2012
Phase 1/2
81
Custirsen (OGX-011) + Gemcitabine + Platinum
zgmheizbrz(qzhepmvwec) = vwnebdlkeu ndxhmiuwhx (fkpozupcka, 21 - 42)
-
01 Mar 2012
Phase 2
70
Docetaxel + Prednisone + Custirsen (DPC)
zbwvzgiwqb(eyqotqafvn) = yalgcchpzp lwlkzihdvl (augtvngosv )
-
01 Sep 2011
Mitoxantrone + Prednisone + Custirsen (MPC)
zbwvzgiwqb(eyqotqafvn) = fejwvsurst lwlkzihdvl (augtvngosv )
Phase 2
82
ttezfejayp(yufclifomk) = dftrojydrd ognfvowfun (wkfienroxh )
-
20 May 2009
ttezfejayp(yufclifomk) = gxnopgxolg ognfvowfun (wkfienroxh )
Phase 2
42
gkchaqrzao(kmaoibyncu) = foeyynjbdh venaopvmro (xufvdozmcb )
-
20 May 2008
gkchaqrzao(kmaoibyncu) = sxjdywkydq venaopvmro (xufvdozmcb )
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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