Last update 31 Mar 2025

AL-8326

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
AL 8326
Action
inhibitors, antagonists
Mechanism
Aurora B inhibitors(Serine/threonine-protein kinase Aurora-B inhibitors), FGFRs antagonists(Fibroblast growth factor receptors antagonists), VEGFR antagonists(Vascular endothelial growth factor receptor antagonists)
Inactive Indication-
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
RegulationBreakthrough Therapy (China), Special Review Project (China)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Small Cell Lung CancerPhase 3
China
26 Oct 2023
Recurrent Lung Small Cell CarcinomaPhase 2
United States
01 Nov 2022
Bile Duct NeoplasmsPhase 1
China
01 Jun 2022
Bladder CancerPhase 1
China
01 Jun 2022
Advanced Lung Non-Small Cell CarcinomaPhase 1
China
03 Dec 2021
Non-Small Cell Lung CancerPhase 1
China
03 Dec 2021
Advanced Cervical CarcinomaPhase 1
China
18 Jan 2021
Endometrial CarcinomaPhase 1
China
18 Jan 2021
Fallopian Tube CarcinomaPhase 1
China
18 Jan 2021
Ovarian CancerPhase 1
China
18 Jan 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
30
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Positive
26 May 2023
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Approval

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Regulation

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