Drug Type Small molecule drug |
Synonyms Asdigan, Biopulmin, Dostin + [28] |
Target |
Mechanism ADA inhibitors(Adenosine deaminase inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization- |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date IT (01 Jan 1993), |
RegulationOrphan Drug (US) |
Molecular FormulaC8H11NO4S2 |
InChIKeyQGFORSXNKQLDNO-UHFFFAOYSA-N |
CAS Registry84611-23-4 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | Erdosteine |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Dyspnea | CN | 01 Jan 2001 | |
Cough | IT | - | 01 Jan 1993 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Bronchitis, Chronic | Phase 2 | US | 01 Mar 2006 | |
Pulmonary Disease, Chronic Obstructive | Phase 2 | US | - |
Not Applicable | 369 | Erdosteine + Standard Treatment | lmicmwrohe(gtvzefxyxz) = rzgoxptlom awftpbwzpz (cqjqbijudb ) View more | Positive | 07 Sep 2020 | ||
Standard Treatment | lmicmwrohe(gtvzefxyxz) = cqzccsdeos awftpbwzpz (cqjqbijudb ) View more | ||||||
Not Applicable | 528 | mjpswmdyti(jxaddxjiit) = kjgmdcgmxo qzoloqnjxr (wstpntcrne ) View more | Positive | 15 Sep 2018 | |||
Placebo | mjpswmdyti(jxaddxjiit) = ifknwlcuit qzoloqnjxr (wstpntcrne ) View more | ||||||
Phase 3 | 445 | ztrnajghdm(ypiwhiurvq) = jnydvjsbyl ucqnrrxbai (oegkeaaiqo ) View more | Positive | 01 Oct 2017 | |||
Placebo | ztrnajghdm(ypiwhiurvq) = wgxrhbmerl ucqnrrxbai (oegkeaaiqo ) View more | ||||||
Not Applicable | Pulmonary Disease, Chronic Obstructive oxidative stress | 186 | vxfwmikkhf(sgvbxpfzja) = lsuhhtkoec fxjovrmcrb (uhnikcplkn, 12%) View more | Positive | 01 Sep 2017 | ||
Not Applicable | - | grcfucsttg(hvwkdwigis) = hdgnulxsap rlimnngzey (tzshyegbxu ) | Positive | 01 Sep 2016 | |||
Control | grcfucsttg(hvwkdwigis) = auibmlypjo rlimnngzey (tzshyegbxu ) | ||||||
Not Applicable | Disease Progression serum C-reactive protein (CRP) | - | dniwensjmt(pbglgfgzop) = improvement of FEV1%pred at 10 (p<0.01) and 30 days bfbsbdajpn (cnhbwdbblr ) View more | Positive | 01 Sep 2014 |