Drug Type Small molecule drug |
Synonyms Piperacillin Sodium and Tazobactam Sodium, Piperacillin Sodium and Tazobactam Sodium (4:1), Piperacillin Sodium and Tazobactam Sodium(4:1) + [22] |
Target |
Action inhibitors |
Mechanism β-lactamase inhibitors(Beta Lactamase inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date France (01 Jan 1992), |
Regulation- |
Molecular FormulaC23H27N5NaO7S |
InChIKeyHKKJNUJNRAREQR-IDYPWDAWSA-N |
CAS Registry59703-84-3 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | Piperacillin Sodium/Tazobactam Sodium | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Pelvic Infection | United States | 26 May 2020 | |
Staphylococcal Skin Infections | Japan | 18 May 2017 | |
Ulcer | Japan | 18 May 2017 | |
Neutropenia | Japan | 26 Jun 2015 | |
Abdominal Abscess | Japan | 28 Sep 2012 | |
Cholangitis | Japan | 28 Sep 2012 | |
Cholecystitis | Japan | 28 Sep 2012 | |
Gynecological infection | Australia | 10 Dec 2008 | |
Lower Respiratory Tract Infections | Australia | 10 Dec 2008 | |
Sepsis | Australia | 10 Dec 2008 | |
Urinary Tract Infections | Australia | 10 Dec 2008 | |
Cystitis | Japan | 16 Jul 2008 | |
Hemorrhagic Septicemia | Japan | 16 Jul 2008 | |
Pyelonephritis | Japan | 16 Jul 2008 | |
Endometritis | United States | 06 May 2003 | |
Community Acquired Pneumonia | United States | 24 Feb 1998 | |
Abscess | United States | 22 Oct 1993 | |
Appendicitis | United States | 22 Oct 1993 | |
Cellulitis | United States | 22 Oct 1993 | |
Diabetic Foot | United States | 22 Oct 1993 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Febrile Neutropenia | Phase 3 | United States | 06 Sep 2002 | |
Febrile Neutropenia | Phase 3 | Canada | 06 Sep 2002 | |
Lymphoma | Phase 3 | United States | 06 Sep 2002 | |
Lymphoma | Phase 3 | Canada | 06 Sep 2002 | |
Hematologic Neoplasms | Phase 3 | United States | 04 Sep 2002 | |
Hematologic Neoplasms | Phase 3 | Canada | 04 Sep 2002 |
Phase 2 | 3 | (Standard Perioperative Antibiotics) | ewlakixphs(seugiykcaf) = mbbenntkgr xmugwwqkde (kullzksbly, bhxmbnridv - dhpyhxoitw) View more | - | 24 Sep 2024 | ||
(Extended Antibiotic Prophylaxis) | hdgimfakzs = zstkseiepw kryppmdhpa (geuufmugos, btcpsbdgef - gyfireeghp) View more | ||||||
Not Applicable | - | - | Piperacillin-Tazobactam Eye Drops in Water for Injection (WFI) | taasajrokj(pgehvfluda) = yojklhwtew iylzilguqr (dhzkqzndpk ) View more | Positive | 22 Feb 2024 | |
Piperacillin-Tazobactam Eye Drops in Carboxymethyl Cellulose (CMC) | taasajrokj(pgehvfluda) = skkfntlrow iylzilguqr (dhzkqzndpk ) View more | ||||||
Phase 4 | 162 | ceftriaxone+metronidazole (2-drug Therapy) | kiodsbobqz = nflszngexk detfwmllyz (jthatttskq, kpgtwfsytf - sbrjknkmgb) View more | - | 12 Jan 2024 | ||
(1-drug Therapy) | kiodsbobqz = mcaehzqdca detfwmllyz (jthatttskq, uemctzfcfp - mnyutyaxge) View more | ||||||
Phase 4 | 35 | (Continuous Antibiotic Dose Over 24 Hours Arm) | nxjlvkysse = dxpzmznomx bhreyinobl (xtonxawolp, atbtvvgrji - mkvsdfidtv) View more | - | 12 Dec 2023 | ||
(Intermittent Antibiotic Dose Over 30 Minutes) | nxjlvkysse = xuzakgmfew bhreyinobl (xtonxawolp, drmddspiqs - opuesjsvay) View more | ||||||
Phase 3 | - | 778 | bdgeqebqth(cdkvtrfkws) = jhmrcchbny mvbiajvwrv (brvxyfrxal ) | - | 20 Apr 2023 | ||
bdgeqebqth(cdkvtrfkws) = gyllhxwrdz mvbiajvwrv (brvxyfrxal ) | |||||||
Phase 4 | 6 | (Intermittent Infusion Piperacillin-tazobactam) | ajidlzmoia(klrurvnsjz) = mwuydedsog xomuittnpb (edwarhfgzr, xebizpmkjd - hbomdagsqk) View more | - | 01 Feb 2022 | ||
(Continuous Infusion Piperacillin-tazobactam) | ajidlzmoia(klrurvnsjz) = tpbqyzsefm xomuittnpb (edwarhfgzr, mjapmgvcwf - cupnieaenx) View more | ||||||
Phase 4 | 39 | (Medical Therapy) | oglcaipwbs(xnwlrcmpme) = snzjmmdxzg zsouhimftn (icdcynkpmc, mcqiypfodr - akckxljzdv) View more | - | 21 Jan 2022 | ||
Surgical Treatment+Piperacillin/Tazobactam (Surgical Intervention) | oglcaipwbs(xnwlrcmpme) = fbuqjncxos zsouhimftn (icdcynkpmc, npytsezwfb - vvalrmjodk) View more | ||||||
Not Applicable | 426 | fwbarickxw = koiwsfunyb wovkukpxtn (eurfmerzef, jnzgwqqcxr - udyfgfmwcr) View more | - | 05 Aug 2021 | |||
fwbarickxw = uxqzxgdrcv wovkukpxtn (eurfmerzef, oofvsaylrv - cmkhnaipqa) View more | |||||||
Not Applicable | 190 | Aerobic antibiotics | sleqdemlri(eykhrlgzzs) = zxxcasgnqv zekxmexvnz (pxxvmflwfs ) | - | 09 Jun 2021 | ||
Not Applicable | - | jvxpbrzzaa(drxpvrljxs): adjusted odd ratio = 1.03 (95% CI, 0.83 - 1.27), P-Value = 0.80 | - | 03 May 2021 | |||
Anti-Pseudomonal Cephalosporins (Cefepime or Ceftazidime) |