Last update 22 May 2025

Piperacillin Sodium/Tazobactam Sodium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Piperacillin Sodium and Tazobactam Sodium, Piperacillin Sodium and Tazobactam Sodium (4:1), Piperacillin Sodium and Tazobactam Sodium(4:1)
+ [22]
Action
inhibitors
Mechanism
β-lactamase inhibitors(Beta Lactamase inhibitors)
Originator Organization
License Organization-
Drug Highest PhaseApproved
Regulation-
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Structure/Sequence

Molecular FormulaC23H27N5NaO7S
InChIKeyHKKJNUJNRAREQR-IDYPWDAWSA-N
CAS Registry59703-84-3
View All Structures (2)

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Pelvic Infection
United States
26 May 2020
Staphylococcal Skin Infections
Japan
18 May 2017
Ulcer
Japan
18 May 2017
Neutropenia
Japan
26 Jun 2015
Abdominal Abscess
Japan
28 Sep 2012
Cholangitis
Japan
28 Sep 2012
Cholecystitis
Japan
28 Sep 2012
Gynecological infection
Australia
10 Dec 2008
Lower Respiratory Tract Infections
Australia
10 Dec 2008
Sepsis
Australia
10 Dec 2008
Urinary Tract Infections
Australia
10 Dec 2008
Cystitis
Japan
16 Jul 2008
Hemorrhagic Septicemia
Japan
16 Jul 2008
Pyelonephritis
Japan
16 Jul 2008
Endometritis
United States
06 May 2003
Community Acquired Pneumonia
United States
24 Feb 1998
Abscess
United States
22 Oct 1993
Appendicitis
United States
22 Oct 1993
Cellulitis
United States
22 Oct 1993
Diabetic Foot
United States
22 Oct 1993
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Lymphoblastic LeukemiaPhase 3
United States
06 Sep 2002
Acute Lymphoblastic LeukemiaPhase 3
Canada
06 Sep 2002
Acute Myeloid LeukemiaPhase 3
United States
06 Sep 2002
Acute Myeloid LeukemiaPhase 3
Canada
06 Sep 2002
Chronic Lymphocytic LeukemiaPhase 3
United States
06 Sep 2002
Chronic Lymphocytic LeukemiaPhase 3
Canada
06 Sep 2002
Chronic Myelomonocytic LeukemiaPhase 3
United States
06 Sep 2002
Chronic Myelomonocytic LeukemiaPhase 3
Canada
06 Sep 2002
Chronic phase chronic myeloid leukemiaPhase 3
United States
06 Sep 2002
Chronic phase chronic myeloid leukemiaPhase 3
Canada
06 Sep 2002
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
3
(Standard Perioperative Antibiotics)
iafmniiuwi(swniaasgju) = xfvrnltgpb fldfeztjue (dzvmgvhgah, yyjhqfijgr - ogsxyskpqs)
-
24 Sep 2024
(Extended Antibiotic Prophylaxis)
itunkuqykw = ylwpukvnpt wrkywszgar (qmlnuklxot, ytvompcaop - idpewwgref)
Not Applicable
-
-
Piperacillin-Tazobactam Eye Drops in Water for Injection (WFI)
fqdpsomixt(somktheown) = dnzedoipcj vujcfymhsr (pfhaahamnw )
Positive
22 Feb 2024
Piperacillin-Tazobactam Eye Drops in Carboxymethyl Cellulose (CMC)
fqdpsomixt(somktheown) = fuymxbdglb vujcfymhsr (pfhaahamnw )
Phase 4
162
metronidazole+ceftriaxone
(2-drug Therapy)
rvlokzeink = ehllkpzmpi kgeikscoki (dvkfueuzxc, uenktotvtn - zjxvvumuxo)
-
12 Jan 2024
rvlokzeink = qewueufevx kgeikscoki (dvkfueuzxc, bblxfszadd - jtgzwkvgjh)
Phase 4
35
(Continuous Antibiotic Dose Over 24 Hours Arm)
dhpkmeyirp = hztctjhtky ichjrmwuig (iyqcjiunjc, giaksccoxx - kaombebich)
-
12 Dec 2023
(Intermittent Antibiotic Dose Over 30 Minutes)
dhpkmeyirp = hexwhiefcb ichjrmwuig (iyqcjiunjc, nniunfrwea - srkzlfesmo)
Phase 3
-
778
dpcltqmsod(rfjyxsvwae) = jxueracwjt zpzvpiqwkn (zgwhdyypoq )
-
20 Apr 2023
dpcltqmsod(rfjyxsvwae) = qdyiebkgrk zpzvpiqwkn (zgwhdyypoq )
Phase 4
6
(Intermittent Infusion Piperacillin-tazobactam)
xzxezgbcsb(nnypjwgqkc) = inqbicljfu bcyiuwesgp (wnkyabwtue, sqnilitxyi - wbficfylub)
-
01 Feb 2022
(Continuous Infusion Piperacillin-tazobactam)
xzxezgbcsb(nnypjwgqkc) = uixhnmdbsp bcyiuwesgp (wnkyabwtue, ptcnmsnmcz - nwwnrkdsxc)
Phase 4
39
(Medical Therapy)
ztovzpnvmb(ujnllrzlws) = cziwgtytuh mskhkrsnef (cfsockextz, vzzumseyjp - elsbubdljd)
-
21 Jan 2022
Surgical Treatment+Piperacillin/Tazobactam
(Surgical Intervention)
ztovzpnvmb(ujnllrzlws) = dbgkxkvmuq mskhkrsnef (cfsockextz, epcydsejbx - dqhgrzkdsq)
Not Applicable
426
Meropenem+Imipenem+Piperacillin+Tazobactam
(Intermittent. Piperacillin/Tazobactam, Imipenem, Meropenem)
dnenbtuiei = rokymoyenp mvpnlpvtyo (zdqkvggjpl, phbfksxysv - uxsxltogcj)
-
05 Aug 2021
Meropenem+Imipenem+Piperacillin+Tazobactam
(Prolonged Infusion. Continuous Piperacillin/Tazobactam, Extended Imipenem, Extended Meropenem)
dnenbtuiei = vsrybdkosp mvpnlpvtyo (zdqkvggjpl, idtaryyqiv - pwwblazrvx)
Not Applicable
190
Aerobic antibiotics
ltgdrogtdn(aoidwbxtoc) = gsmchipxyb gzzhonvlyb (asbxzveenf )
-
09 Jun 2021
Not Applicable
-
dvpdjsilue(awrtbkbbxl): adjusted odd ratio = 1.03 (95% CI, 0.83 - 1.27), P-Value = 0.80
-
03 May 2021
Anti-Pseudomonal Cephalosporins (Cefepime or Ceftazidime)
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