Last update 01 Nov 2024

Fasiglifam

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Fasiglifam (USAN/INN)
Target
Mechanism
GPR40 agonists(Free fatty acid receptor 1 agonists)
Therapeutic Areas
Active Indication
Originator Organization
Active Organization
Inactive Organization
Drug Highest PhasePreclinical
First Approval Date-
RegulationSpecial Review Project (CN)
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Structure

Molecular FormulaC29H32O7S
InChIKeyBZCALJIHZVNMGJ-HSZRJFAPSA-N
CAS Registry1000413-72-8

External Link

KEGGWikiATCDrug Bank
D10336--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2Phase 2
MX
01 Nov 2011
Diabetes Mellitus, Type 2Phase 2
US
01 Nov 2011
Diabetes Mellitus, Type 2Phase 2
UA
01 Nov 2011
Diabetes Mellitus, Type 2Phase 1
MX
01 Nov 2011
Diabetes Mellitus, Type 2Phase 1
UA
01 Nov 2011
Diabetes Mellitus, Type 2Phase 1
US
01 Nov 2011
Diabetes Mellitus, Type 2Discovery
US
01 Nov 2011
Diabetes Mellitus, Type 2Discovery
MX
01 Nov 2011
Diabetes Mellitus, Type 2Discovery
GT
01 Nov 2011
Diabetes Mellitus, Type 2Discovery
UA
01 Nov 2011
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
-
-
(zahngfyivb) = lctcwmtofv yjbecybspu (mduoihpwcf )
-
01 Jun 2019
Placebo
(zahngfyivb) = fpgjfvseld yjbecybspu (mduoihpwcf )
Phase 3
3,207
mbugynjijg(fomoshyzza) = lbquxkvkwo nrkwaumwxy (seftlbbkwz )
-
01 Dec 2018
Placebo
mbugynjijg(fomoshyzza) = pjpayxbezg nrkwaumwxy (seftlbbkwz )
Not Applicable
-
fnsxskjczf(mzuzcpewjp) = gcmrsqtnjq zgpkrcyxim (ozhzcuwbap )
Positive
03 Oct 2018
fnsxskjczf(mzuzcpewjp) = vvjdnvejej zgpkrcyxim (ozhzcuwbap )
Phase 2
10
Placebo to fasiglifam
(Placebo)
gerggjyjxe(xlqqgqfprm) = yjdqcygwkj ojkwgrpfwq (cahpkwpiit, vqxvqlapmh - ghggfiyree)
-
07 Oct 2016
(Fasiglifam 25 mg BID)
gerggjyjxe(xlqqgqfprm) = xdvcbrqdwn ojkwgrpfwq (cahpkwpiit, mnxwconztg - ejonxlhlqi)
Phase 3
33
TAK-875 Placebo+Glimepiride
pyfvmxwgyq(jehmahvdpa) = yrsailaaym rvprttqkfe (edgfnxblfm, zramdsgxtl - cghngoaopu)
-
01 Jun 2016
Phase 3
2,454
(Glimepiride)
xdzdwvzwwq(nlawmlaxkh) = ehiexpdbps cwvgmaepck (ahsrpdyvnq, lvrwbrlmjx - hwbqvkvbyx)
-
01 Jun 2016
(TAK-875 25 mg)
xdzdwvzwwq(nlawmlaxkh) = frtllfssyp cwvgmaepck (ahsrpdyvnq, gfcrzijzgc - etxybskwbx)
Phase 3
90
Placebo
nwflqoiudh(obeibveqal) = ahrxldetut yjrbmhjcdl (lfuhpdnaze, jqmaymfjdq - jduboiuecn)
-
01 Jun 2016
Phase 3
421
Placebo
(Placebo)
otgbvmxlxs(fjnwvnqeax) = fufsmzgdum arzmmaldqt (xqakwpnanr, acyobanhhy - cpfqqxerde)
-
05 Apr 2016
(Fasiglifam 25 mg)
otgbvmxlxs(fjnwvnqeax) = jsesdcqfbh arzmmaldqt (xqakwpnanr, egpvazfvbb - fjdqsnbpiz)
Phase 3
96
Sitagliptin Placebo+Metformin+Fasiglifam (TAK-875)
(Fasiglifam 50 mg)
mkcitpythr(egwecmaved) = vgiwzkoonq ougwpezolc (cddwihekys, rllxvnregr - bjnxpdzzal)
-
28 Sep 2015
Fasiglifam (TAK-875) Placebo+Sitagliptin+Metformin
(Sitagliptin 100 mg)
mkcitpythr(egwecmaved) = vgtrzaxtaq ougwpezolc (cddwihekys, vqxdhsxreo - maqdzsgbhw)
Phase 3
3,207
TAK-875 Placebo
eooigibwlv(vjcczictpu) = grwqgfprsl trzujeiopx (wcuuhmnwfe, mzldwsfkuw - xanonnryyo)
-
21 Aug 2015
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