Drug Type Small molecule drug |
Synonyms Avandamet, Avandamet XR, Metformin Hydrochloride and Rosiglitazone Maleate + [5] |
Target |
Mechanism PPARγ agonists(Peroxisome proliferator-activated receptor γ agonists), PRKAB1 activators(Protein kinase AMP-activated non-catalytic subunit beta 1 activators) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date US (10 Oct 2002), |
Regulation- |
Molecular FormulaC26H35ClN8O7S |
InChIKeyUABJPASVFPMIGE-KWZUVTIDSA-N |
CAS Registry622402-70-4 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Diabetes Mellitus, Type 2 | US | 10 Oct 2002 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Diabetes Mellitus, Noninsulin-Dependent, 2 | Phase 3 | BE | 01 Feb 2004 | |
Diabetes Mellitus, Noninsulin-Dependent, 2 | Phase 3 | FR | 01 Feb 2004 | |
Diabetes Mellitus, Noninsulin-Dependent, 2 | Phase 3 | DE | 01 Feb 2004 | |
Diabetes Mellitus, Noninsulin-Dependent, 2 | Phase 3 | IE | 01 Feb 2004 | |
Diabetes Mellitus, Noninsulin-Dependent, 2 | Phase 3 | IT | 01 Feb 2004 | |
Diabetes Mellitus, Noninsulin-Dependent, 2 | Phase 3 | LT | 01 Feb 2004 | |
Diabetes Mellitus, Noninsulin-Dependent, 2 | Phase 3 | MX | 01 Feb 2004 | |
Diabetes Mellitus, Noninsulin-Dependent, 2 | Phase 3 | NL | 01 Feb 2004 | |
Diabetes Mellitus, Noninsulin-Dependent, 2 | Phase 3 | ES | 01 Feb 2004 | |
Diabetes Mellitus, Noninsulin-Dependent, 2 | Phase 3 | CH | 01 Feb 2004 |
Phase 3 | 391 | (Avandia and Amaryl) | efyyxqfpmf(lpwcfhiqej) = xatdnlpfzf fuabgjdgsi (nyygycmsyd, daelshnhux - hdljhcahpf) View more | - | 17 Apr 2013 | ||
(Avandamet) | efyyxqfpmf(lpwcfhiqej) = jqrrluclmf fuabgjdgsi (nyygycmsyd, drualdzsew - wuurtaiwcz) View more | ||||||
Phase 1 | 26 | Rosiglitazone Maleate (Test Product) | oybwixqbam(ripotvqnmh) = jrgcjkncrp herztzwoog (noqmcvgksu, usoyaxarkk - cyqczvfjhm) View more | - | 08 Apr 2011 | ||
Rosiglitazone Maleate (Reference Product) | oybwixqbam(ripotvqnmh) = txyecnrehl herztzwoog (noqmcvgksu, lypsyvmpxq - gyclqatxgq) View more | ||||||
Phase 4 | 688 | ofvchuiitc(kicchowvvx) = mylcixqwqm oqnitwkksd (hgzxfajhmf, vzuihdahue - vgvxhfwzvd) View more | - | 05 Apr 2011 |